Clinical and demographic baseline characteristics.

a<p>Chi-square test.</p>b<p>Student <i>t</i>-test.</p>c<p>Mann-Whitney <i>U</i> test.</p><p>Abbreviations: EDSS: Expanded Disability Scale; IQR: interquartile range; SD: standard deviation.</p><p>Clinical and demographic baseline characteristics.</p

Survival curve for the time to the next relapse using the 1.096 threshold.

<p>Patients belonging to the low-MxA group (MxA <1.096) showed a significantly longer time to the next relapse (p<0.0001).</p

Survival curve for the time to EDSS progression using the 1.096 threshold.

<p>Patients belonging to the low-MxA group (MxA <1.096) showed a significantly longer time to increase by one point on the EDSS scale (p = 0.01).</p