Kajian Kritis Makalah Ilmiah Kedokteran Klinik Menurut Kedokteran Berbasis Bukti (KKB)

xiii, 159 hlm.; 28 cm

Association between the absence of colostrum feeding and symptoms of intestinal obstruction or neonatal necrotizing enterocolitis

Objective To assess the relationship between withholding colos- trum and symptoms of intestinal obstruction (SIO) or neonatal ne- crotizing enterocolitis (NNEC). Methods This was a longitudinal cohort study in four subdistricts in West Lombok involving mothers and live newborns. Mothers were interviewed about prenatal care, delivery process, and prac- tice of colostrum feedings. Neonates were followed everyday for 28 days by field assistants for signs of intestinal obstruction or NNEC. We used X 2 test to analyze the association between the absence of colostrum feeding and the occurence of SIO and stu- dent t test to compare the average of colostrum feeding between the SIO and the non-SIO group. Results 3420 live newborns between 1993-1994 were observed. 1900 mothers gave colostrum while 1520 did not. The incidence of SIO was 1.8%. There was a significant association between the absence of colostrum feeding and the occurence of the SIO (RR 1.816; 95%CI 1.08-3.06; p=0.028). No infants with NNEC were given colostrum. Conclusion The absence of colostrum feeding is an important risk factor for the occurence of SIO and NNEC in neonate

Association between early feeding of banana (Musa paradisiaca) and vomiting or abdominal distention in neonates

Objective To assess the relationship between banana given as early solid food feeding and symptoms of intestinal obstruction (SIO) such as vomiting and abdominal distention among neonates. Methods A longitudinal cohort study was done in 1993 at a rural community of West Lombok District on Lombok Island, West Nusa Tenggara Province, Indonesia. There were 3420 neonates who were followed up by interviewing their mothers until 28 days after delivery. The main outcome measure was the occurrence of SIO. Results Compared to infants who were not given solid food, the relative risk (RR) of SIO for infants given food other than banana as early solid food feeding was 1.87 (95%CI 0.48;8.24), while for infants given banana only as early solid food feeding, the RR was 9.15 (95%CI 1.96;42.58). After the adjustments of birth weight, co- lostrum, and breast feeding, the odds ratio of SIO for infants given banana was 2.99 (95%CI 2.65;5.14). Conclusion Banana as early solid food for neonates feeding is an important risk factor for the occurrence of SI