PENGGUNAAN EKSTRAK ETANOL KULIT BUAH MANGGIS (Garcinia mangostana) SEBAGAI LARVISIDA TERHADAP LARVA NYAMUK Culex quinquefasciatus

Background. Lymphatic Filariasis is disease caused by parasite whereas 120 million people who live in tropic and subtropic area already infected. Its transmission is via mosquito bite so controlling mosquito using synthetic insecticide becoming usual. However, using synthetic insecticide extensively causes enviranmental pollution and resistency. Therefore, it is important to find alternative larvicide which is safe and natural. In daily routine, mangosteen pericarp is rarely use while it contain alpha mangostin which can be used as larvicide. Objectives. To explore effect of Garcinia mangostana pericarp with ethanol extract as larvicide against larvae of Culex quinquefasciatus. Methode. This research uses simple experimental research design. Instar III-IV larvae divided into 7 treatment group and 1 control group with each group consist of 10 larvae with three times replication, in 10 ml solution. Larvae mortality counted after 24 hours and the data analyzed using probit analysis and ONE WAY ANOVA. Results. The LC50 dan LC90 values were 3.147,99 ppm and 9.983,82ppm dosage of the extract. Conclusion. Ethanol extraction of mangosteen (Garcinia mangostana) pericarp has larvicide effect against instar III-IV Culex quinquefasciatus mosquito and increasing its concentration result in increased larvae mortality but ineffective

UJI EFEKTIFITAS LARVISIDA INFUSA KULIT BUAH MANGGIS (Garcinia mangostana L) TERHADAP LARVA NYAMUK Culex quinquefasciatus

Background. Elephantiasis has become epidemic in tropical countries. This disease transmitted through mosquito bite, mainly by Culex quinquefasciatus. Mangosteen skin is expected to have larvicidal effect such as alpha-mangostin. Objective. To determine the potent larvicidal activity (LC50 and LC90) of Garcinia mangostana L infusio

EKSTRAK ETER KULIT BUAH MANGGIS (Garcinia mangostana) TERHADAP LARVA NYAMUK Culex quinquefasciatus

Background: In recent, infection of lymphatic filariasis is a disease that is very common in Indonesia caused by Wucheria bancrofti. The main vector of filariasis is Culex quinquefasciatus . The main way to control the incidence of infectious disease lymphatic filariasis is to break the chain of the life cycle of the vector. Larvicidal natural and easy to find in the community for example is the pericarp of the mangosteen fruit (Garcinia mangostana L.) is used as a natural larvicidal. Objective: This study was made to determine the effect of the ether extract of mangosteen (Garcinia mangostana L.) pericarp against Culex quinquefasciatus�s larvae mortality . Methods: The study was performed using simple experimental study using WHO 2005 as the guide. Research for the initial test was performed to determine the range of 6 concentrations (2000 ppm, 4000 ppm, 8000 ppm, 11.000 ppm, 15.000 ppm, 18.000 ppm,) treatment performed 3 times at the end of the test using 10 larvae at each concentration in 100 ml. The final result is analyzed wih Probit and ANOVA. Results: LC50 is in 4626,964 ppm dosage of the extract and LC90 is in 16770,38 ppm. Conclusion:Ether extract of mangosteen (Garcinia mangostana L.) pericarp has a larvicidal against Culex quinquefasciatus�s larvae, but not effective