MPS - Decision Support System for Multiobjective Project Scheduling

The report presents a decision support system (DSS) for multiobjective project scheduling under multiple-category resource constraints. It handles quite a general class of nonpreemptive scheduling problems with renewable, nonrenewable and doubly-constrained resources, multiple performing modes of activities, precedence constraints in the form of an activity network and multiple project performance criteria of time and cost type. The DSS has been implemented on a microcomputer compatible with IBM PC, and called MPS. It is based on three kinds of heuristics: parallel priority rules, simulated annealing and branch-and-bound. The last algorithm can even yield exact solutions when sufficient processing time is available. Some parts of the MPS are interactive, in particular, the search for a best compromise schedule. Graphical facilities enable a thorough evaluation of feasible schedules. The report starts with a methodological guide presenting the problem formulation and the three heuristics. Then, the general scheme of the MPS is given together with an executive guide. An expanding menu and all its options are described and illustrated with a simple example. The last part presents a real problem solving consisting in scheduling 40 farm activities

Comparing the Evolution, Form, and Function of Russian and Chinese Information Operations

Russia and China are critical actors who deploy far-reaching and impactful information operations in pursuit of their national interests. Their use of information operations is multifaceted and should be subject to study due to how influential these operations are and how significant the effects can be. In pursuit of this knowledge, the aim of this study was to conduct an in-depth analysis of these two countries\u27 information operations and how their operations differ. The first area analyzed was the evolution of these countries\u27 modern day information operations, primarily looking for the factors and historical context which influenced the development of their information operations. The modern day form of these information operations was then examined using the Chinese model of the Three Warfares, which is broken down into legal, psychological, and media warfare. After evaluating these nations through this lens, the common goals, targets, and narrative themes of Russian and Chinese information operations were able to be identified. A cross comparison of the evolution, form, and function of two nation\u27s information operations was conducted and this found that both nations utilize information operations to either support physical action or replace the use of physical action. While both nations use information operations to maintain and grow their influence, Russia uses these operations to suppress Western power and China uses them to protect its reputation

Scanning Electrochemical Microscopy of DNA Monolayers Modified with Nile Blue

Scanning electrochemical microscopy (SECM) is used to probe long-range charge transport (CT) through DNA monolayers containing the redox-active Nile Blue (NB) intercalator covalently affixed at a specific location in the DNA film. At substrate potentials negative of the formal potential of covalently attached NB, the electrocatalytic reduction of Fe(CN)63− generated at the SECM tip is observed only when NB is located at the DNA/solution interface; for DNA films containing NB in close proximity to the DNA/electrode interface, the electrocatalytic effect is absent. This behavior is consistent with both rapid DNA-mediated CT between the NB intercalator and the gold electrode as well as a rate-limiting electron transfer between NB and the solution phase Fe(CN)63−. The DNA-mediated nature of the catalytic cycle is confirmed through sequence-specific and localized detection of attomoles of TATA-binding protein, a transcription factor that severely distorts DNA upon binding. Importantly, the strategy outlined here is general and allows for the local investigation of the surface characteristics of DNA monolayers both in the absence and in the presence of DNA binding proteins. These experiments highlight the utility of DNA-modified electrodes as versatile platforms for SECM detection schemes that take advantage of CT mediated by the DNA base pair stack

Diversification rates and phenotypic evolution in venomous snakes (Elapidae)

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.The relationship between rates of diversification and of body size change (a common proxy for phenotypic evolution) was investigated across Elapidae, the largest radiation of highly venomous snakes. Time-calibrated phylogenetic trees for 175 species of elapids (more than 50% of known taxa) were constructed using seven mitochondrial and nuclear genes. Analyses using these trees revealed no evidence for a link between speciation rates and changes in body size. Two clades (Hydrophis, Micrurus) show anomalously high rates of diversification within Elapidae, yet exhibit rates of body size evolution almost identical to the general elapid ‘background’ rate. Although correlations between speciation rates and rates of body size change exist in certain groups (e.g. ray-finned fishes, passerine birds), the two processes appear to be uncoupled in elapid snakes. There is also no detectable shift in diversification dynamics associated with the colonization of Australasia, which is surprising given that elapids appear to be the first clade of venomous snakes to reach the continent

Artificial Intelligence and Intellectual Property Law - Position Statement of the Max Planck Institute for Innovation and Competition of 9 April 2021 on the Current Debate

This Position Statement presents a broad overview of issues arising at the intersection of AI and IP law based on the work of the Max Planck Institute for Innovation and Competition research group on Regulation of the Digital Economy. While the analysis is approached mainly from a perspective de lege lata, it also identifies questions which require further reflection de lege ferenda supported by in-depth interdisciplinary research. The scope is confined to substantive European IP law, in particular, as regards copyright, patents, designs, databases and trade secrets. Specific AI-related issues are mapped out around the core questions of IP law, namely, the eligibility for protection under the respective IP regimes, allocation of rights and the scope of protection. The structure of the analysis reflects three key components of AI: inputs required for the development of AI systems, AI as a process and the output of AI applications. Overall, it is emphasised that, while recent legal and policy discussions have mostly focused on AI-aided and AI-generated output, a more holistic view that accounts for the role of IP law across the AI innovation cycle is indispensable