Subclass Discriminant Analysis of Morphological and Textural Features for HEp-2 Staining Pattern Classification

Classifying HEp-2 fluorescence patterns in Indirect Immunofluorescence (IIF) HEp-2 cell imaging is important for the differential diagnosis of autoimmune diseases. The current technique, based on human visual inspection, is time-consuming, subjective and dependent on the operator's experience. Automating this process may be a solution to these limitations, making IIF faster and more reliable. This work proposes a classification approach based on Subclass Discriminant Analysis (SDA), a dimensionality reduction technique that provides an effective representation of the cells in the feature space, suitably coping with the high within-class variance typical of HEp-2 cell patterns. In order to generate an adequate characterization of the fluorescence patterns, we investigate the individual and combined contributions of several image attributes, showing that the integration of morphological, global and local textural features is the most suited for this purpose. The proposed approach provides an accuracy of the staining pattern classification of about 90%

Geodesic-Preserving Polygon Simplification

Polygons are a paramount data structure in computational geometry. While the complexity of many algorithms on simple polygons or polygons with holes depends on the size of the input polygon, the intrinsic complexity of the problems these algorithms solve is often related to the reflex vertices of the polygon. In this paper, we give an easy-to-describe linear-time method to replace an input polygon $\mathcal{P}$ by a polygon $\mathcal{P}'$ such that (1) $\mathcal{P}'$ contains $\mathcal{P}$, (2) $\mathcal{P}'$ has its reflex vertices at the same positions as $\mathcal{P}$, and (3) the number of vertices of $\mathcal{P}'$ is linear in the number of reflex vertices. Since the solutions of numerous problems on polygons (including shortest paths, geodesic hulls, separating point sets, and Voronoi diagrams) are equivalent for both $\mathcal{P}$ and $\mathcal{P}'$, our algorithm can be used as a preprocessing step for several algorithms and makes their running time dependent on the number of reflex vertices rather than on the size of $\mathcal{P}$

Planar Visibility: Testing and Counting

In this paper we consider query versions of visibility testing and visibility counting. Let $S$ be a set of $n$ disjoint line segments in $\R^2$ and let $s$ be an element of $S$. Visibility testing is to preprocess $S$ so that we can quickly determine if $s$ is visible from a query point $q$. Visibility counting involves preprocessing $S$ so that one can quickly estimate the number of segments in $S$ visible from a query point $q$. We present several data structures for the two query problems. The structures build upon a result by O'Rourke and Suri (1984) who showed that the subset, $V_S(s)$, of $\R^2$ that is weakly visible from a segment $s$ can be represented as the union of a set, $C_S(s)$, of $O(n^2)$ triangles, even though the complexity of $V_S(s)$ can be $\Omega(n^4)$. We define a variant of their covering, give efficient output-sensitive algorithms for computing it, and prove additional properties needed to obtain approximation bounds. Some of our bounds rely on a new combinatorial result that relates the number of segments of $S$ visible from a point $p$ to the number of triangles in $\bigcup_{s\in S} C_S(s)$ that contain $p$.Comment: 22 page

A Nearly Optimal Algorithm for covering the interior of an Art Gallery

The problem of locating visual sensors can be often modeled as 2D Art Gallery problems. In particular, tasks such as surveillance require observing the interior of a polygonal environment (interior covering, IC), while for inspection or image based rendering observing the boundary (edge covering, EC) is sufficient. Both problems are NP-hard, and no technique is known for transforming one problem into the other. Recently, an incremental algorithm for EC has been proposed, and its near-optimality has been demonstrated experimentally. In this paper we show that, with some modification, the algorithm is nearly optimal also for IC. The algorithm has been implemented and tested over several hundreds of random polygons with and without holes. The cardinality of the solutions provided is very near to, or coincident with, a polygon-specific lower bound, and then suboptimal or optimal. In addition, our algorithm has been compared, for all the test polygons, with recent heuristic sensor location algorithms. In all cases, the cardinality of the set of guards provided by our algorithm was less than or equal to that of the set computed by the other algorithms. An enhanced version of the algorithm, also taking into account range and incidence constraints, has also been implemente