3,248 research outputs found

    The public face of event volunteering at the 2006 Commonwealth Games The media perspective

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    Volunteers play a major role in mega and major events, both cultural and sporting, contributing invaluable human resources. Frequently described (and, maybe, over-emphasised) as the 'unsung heroes' of such events, relatively little is known about this group of workers when compared with volunteers who give regular and long-term commitment to their area of interest. This paper focuses on media representation and perceptions of volunteering at the 2006 Commonwealth Games in Melbourne. The exploratory study adopts an extended timeframe and reports on media representation of volunteers over the full event cycle from recruitment through training and the actual event, concluding with consideration of the Games' aftermath. The findings highlight various positive and negative aspects of the media representation of volunteering at this type of mega event and how this has the potential to influence its public face. Conclusions focus on the implications for the media management of volunteering at major events and suggestions for future research in this area

    If money talks, what does it say? Varieties of capitalism and business financing of parties

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    Do business contributions to political parties convey different messages in different countries, and, if so, why? This is the first cross-national study of firm behaviour in political finance. It understands motivations for contributions to parties as either ideological or pragmatic. Motivation is inferred by quantitatively relating the payments of 960 firms to variations in political competition in three countries over periods of between seven and seventeen years. In co-ordinated Germany, a small number of firms make ideological payments. In liberal Canada and Australia, large numbers of firms made pragmatic payments. Australia’s left-right party system created an awareness of policy risk, which motivated ideological payments, but there was no ideological bias in business financing of politics in Canada’s unusually non-ideological party system. The statistical analysis is supplemented by a qualitative investigation of discrete and reciprocal exchanges between businesses and political parties

    Slot or Table? A Chinese Perspective

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    Metformin Treatment Attenuates Brain Inflammation and Rescues PACAP/VIP Neuropeptide Alterations in Mice Fed a High-Fat Diet.

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    High-fat diet (HFD)-induced comorbid cognitive and behavioural impairments are thought to be the result of persistent low-grade neuroinflammation. Metformin, a first-line medication for the treatment of type-2 diabetes, seems to ameliorate these comorbidities, but the underlying mechanism(s) are not clear. Pituitary adenylate cyclase-activating peptide (PACAP) and vasoactive intestinal peptide (VIP) are neuroprotective peptides endowed with anti-inflammatory properties. Alterations to the PACAP/VIP system could be pivotal during the development of HFD-induced neuroinflammation. To unveil the pathogenic mechanisms underlying HFD-induced neuroinflammation and assess metformin's therapeutic activities, (1) we determined if HFD-induced proinflammatory activity was present in vulnerable brain regions associated with the development of comorbid behaviors, (2) investigated if the PACAP/VIP system is altered by HFD, and (3) assessed if metformin rescues such diet-induced neurochemical alterations. C57BL/6J male mice were divided into two groups to receive either standard chow (SC) or HFD for 16 weeks. A further HFD group received metformin (HFD + M) (300 mg/kg BW daily for 5 weeks) via oral gavage. Body weight, fasting glucose, and insulin levels were measured. After 16 weeks, the proinflammatory profile, glial activation markers, and changes within the PI3K/AKT intracellular pathway and the PACAP/VIP system were evaluated by real-time qPCR and/or Western blot in the hypothalamus, hippocampus, prefrontal cortex, and amygdala. Our data showed that HFD causes widespread low-grade neuroinflammation and gliosis, with regional-specific differences across brain regions. HFD also diminished phospho-AKT(Ser473) expression and caused significant disruptions to the PACAP/VIP system. Treatment with metformin attenuated these neuroinflammatory signatures and reversed PI3K/AKT and PACAP/VIP alterations caused by HFD. Altogether, our findings demonstrate that metformin treatment rescues HFD-induced neuroinflammation in vulnerable brain regions, most likely by a mechanism involving the reinstatement of PACAP/VIP system homeostasis. Data also suggests that the PI3K/AKT pathway, at least in part, mediates some of metformin's beneficial effects

    Gambling-machines and the Automation of Desire

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    This paper deals with the relationship between gamblers and Electronic Gaming Machines (EGMs), which leads to the automation of desire through procedures. "Pokies", as EGMs are known in the Australian context, are both desiring­machines (Deleuze and Guattari) and cross­platform media where digital gambling and videogame conventions and procedures intersect. I make a case that, as desiring­machines (entities that are defined by their connections), pokies and gamblers form couplings that generate assemblages, which are "passional", "a composition of desire" (Deleuze and Guattari). I also argue that pokies share aesthetic and procedural similarities with videogames and that the gameplay's objective is not always to merely win money, but to fulfil a desire to accomplish missions and embark on adventures. I also argue that these "missions" are related to chasing, the overarching procedure that defines EGM consumption and allows for the automation of gambler­pokie couplings. The aesthetics of most of these procedure­ images can be traced back to a postcolonial disposition over foreign lands, peoples and cultures ­faux Chinese and Aboriginal lore, exotic deserts, untamed jungles and Arctic landscapes that need to be conquered. This disposition echoes notions such as class­ related aspiration (desire) and exotica. I analyse the imagery in some of the pokies that circulate in the New South Wales (Australia) EGM market. This reading of Electronic Gaming Machines adds a ludic dimension to the analysis of a highly class­bound social practice that is part of a wider socioeconomic trend that points towards a new and contradictory consumption ethic. The application of videogame theory is absent in current discussions on poker machine interfaces and legislation, which generally focus on the figure of the pathological gambler and disregard the complexities of gambling platforms

    Borderline bodies

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    This chapter is about borders that are made and broken at gay pride parades. Specifically, I examine the discursive and material borders maintained in tourism discourse. Binary oppositions such as self/other, straight/gay, and tourist/host provide a focus for this chapter. I am interested in where these borders wear thin and threaten to break and disrupt social order. I explore the bodies of gay pride parades because it is bodies such as these that threaten the borders of corporeal acceptability

    Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment

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    Purpose Systemic increases in reactive oxygen species, and their association with inflammation, have been proposed as an underlying mechanism linking obesity and age-related macular degeneration (AMD). Studies have found increased levels of oxidative stress biomarkers and inflammatory cytokines in obese individuals; however, the correlation between obesity and retinal inflammation has yet to be assessed. We used the leptin-deficient (ob/ob) mouse to further our understanding of the contribution of obesity to retinal oxidative stress and inflammation.This study was supported by an Australian Government Research Training Program (RTP) Scholarship

    Pancreatic Polypeptide Controls Energy Homeostasis via Npy6r Signaling in the Suprachiasmatic Nucleus in Mice

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    SummaryY-receptors control energy homeostasis, but the role of Npy6 receptors (Npy6r) is largely unknown. Young Npy6r-deficient (Npy6r−/−) mice have reduced body weight, lean mass, and adiposity, while older and high-fat-fed Npy6r−/− mice have low lean mass with increased adiposity. Npy6r−/− mice showed reduced hypothalamic growth hormone releasing hormone (Ghrh) expression and serum insulin-like growth factor-1 (IGF-1) levels relative to WT. This is likely due to impaired vasoactive intestinal peptide (VIP) signaling in the suprachiasmatic nucleus (SCN), where we found Npy6r coexpressed in VIP neurons. Peripheral administration of pancreatic polypeptide (PP) increased Fos expression in the SCN, increased energy expenditure, and reduced food intake in WT, but not Npy6r−/−, mice. Moreover, intraperitoneal (i.p.) PP injection increased hypothalamic Ghrh mRNA expression and serum IGF-1 levels in WT, but not Npy6r−/−, mice, an effect blocked by intracerebroventricular (i.c.v.) Vasoactive Intestinal Peptide (VPAC) receptors antagonism. Thus, PP-initiated signaling through Npy6r in VIP neurons regulates the growth hormone axis and body composition

    Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects

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    The aim of the present study was to determine the effects on blood pressure response of 50 g carbohydrate drinks with differing glycaemic effects in ten healthy elderly subjects (age >65 years; randomized crossover design). Systolic (SBP), diastolic (DBP) and mean arterial (MAP) blood pressure, heart rate and plasma glucose levels were determined following ingestion of equal volumes (379 ml) of water and 50 g carbohydrate drinks with differing reported glycaemic indices (GI) (surrogate marker for glycaemic effect): (1) low-GI: Apple & Cherry Juice; (2) intermediate-GI: Fanta Orange; (3) high-glucose. Glucose (SBP and DBP P,0·001; MAP P¼0·005) and Fanta Orange (SBP P¼0·005; DBP and MAP P,0·001) ingestion caused a significant decrease in BP whilst blood pressure increased (SBP P¼0·008; MAP P¼0·005) from baseline following Apple & Cherry Juice ingestion. Water had no significant effect on postprandial blood pressure. Fanta Orange and Apple & Cherry Juice caused similar (P¼0·679) glycaemic effects, which were significantly greater than water, but lower than glucose (P,0·001). There was no significant correlation between the glycaemic effect of the carbohydrate drinks and there was no change in blood pressure from baseline (SBP r 20·123, P¼0·509; DBP r 20·051, P¼0·784; MAP r 20·069, P¼0·712). Apple & Cherry Juice and Fanta Orange had similar glycaemic effects, but differing effects on blood pressure. Therefore, it is unlikely that the glycaemic effect of a drink can be used to predict the subsequent cardiovascular response.Renuka Visvanathan, Richard Chen, Michael Horowitz and Ian Chapma
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