One-class classifiers based on entropic spanning graphs

One-class classifiers offer valuable tools to assess the presence of outliers in data. In this paper, we propose a design methodology for one-class classifiers based on entropic spanning graphs. Our approach takes into account the possibility to process also non-numeric data by means of an embedding procedure. The spanning graph is learned on the embedded input data and the outcoming partition of vertices defines the classifier. The final partition is derived by exploiting a criterion based on mutual information minimization. Here, we compute the mutual information by using a convenient formulation provided in terms of the $\alpha$-Jensen difference. Once training is completed, in order to associate a confidence level with the classifier decision, a graph-based fuzzy model is constructed. The fuzzification process is based only on topological information of the vertices of the entropic spanning graph. As such, the proposed one-class classifier is suitable also for data characterized by complex geometric structures. We provide experiments on well-known benchmarks containing both feature vectors and labeled graphs. In addition, we apply the method to the protein solubility recognition problem by considering several representations for the input samples. Experimental results demonstrate the effectiveness and versatility of the proposed method with respect to other state-of-the-art approaches.Comment: Extended and revised version of the paper "One-Class Classification Through Mutual Information Minimization" presented at the 2016 IEEE IJCNN, Vancouver, Canad

Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

Dense 3D Face Correspondence

We present an algorithm that automatically establishes dense correspondences between a large number of 3D faces. Starting from automatically detected sparse correspondences on the outer boundary of 3D faces, the algorithm triangulates existing correspondences and expands them iteratively by matching points of distinctive surface curvature along the triangle edges. After exhausting keypoint matches, further correspondences are established by generating evenly distributed points within triangles by evolving level set geodesic curves from the centroids of large triangles. A deformable model (K3DM) is constructed from the dense corresponded faces and an algorithm is proposed for morphing the K3DM to fit unseen faces. This algorithm iterates between rigid alignment of an unseen face followed by regularized morphing of the deformable model. We have extensively evaluated the proposed algorithms on synthetic data and real 3D faces from the FRGCv2, Bosphorus, BU3DFE and UND Ear databases using quantitative and qualitative benchmarks. Our algorithm achieved dense correspondences with a mean localisation error of 1.28mm on synthetic faces and detected $14$ anthropometric landmarks on unseen real faces from the FRGCv2 database with 3mm precision. Furthermore, our deformable model fitting algorithm achieved 98.5% face recognition accuracy on the FRGCv2 and 98.6% on Bosphorus database. Our dense model is also able to generalize to unseen datasets.Comment: 24 Pages, 12 Figures, 6 Tables and 3 Algorithm