Aspect Mining for Drug Recommendation: A Survey

Now a days due to this computerized world all the information related to the patients queries are available on internet. This survey paper compares various research issues and few techniques related to the user query for their drug discovery. These reviews helps users to know more about the drug dosage, their side-effects and also specifications. Reviews provides positive as well as negative feedback, Hence these reviews also plays an important role for patients and pharmaceutical industries. The probabilistic aspect mining model (PAMM) identifies aspects according to the class labels. PAMM finds aspects related to one class instead of finding aspects for all classes simultaneously in each execution. PAMM also find aspects measured using the mean point wise mutual information .Hence mixing concepts of different class label gets avoided

RECOMED: A Comprehensive Pharmaceutical Recommendation System

A comprehensive pharmaceutical recommendation system was designed based on the patients and drugs features extracted from Drugs.com and Druglib.com. First, data from these databases were combined, and a dataset of patients and drug information was built. Secondly, the patients and drugs were clustered, and then the recommendation was performed using different ratings provided by patients, and importantly by the knowledge obtained from patients and drug specifications, and considering drug interactions. To the best of our knowledge, we are the first group to consider patients conditions and history in the proposed approach for selecting a specific medicine appropriate for that particular user. Our approach applies artificial intelligence (AI) models for the implementation. Sentiment analysis using natural language processing approaches is employed in pre-processing along with neural network-based methods and recommender system algorithms for modeling the system. In our work, patients conditions and drugs features are used for making two models based on matrix factorization. Then we used drug interaction to filter drugs with severe or mild interactions with other drugs. We developed a deep learning model for recommending drugs by using data from 2304 patients as a training set, and then we used data from 660 patients as our validation set. After that, we used knowledge from critical information about drugs and combined the outcome of the model into a knowledge-based system with the rules obtained from constraints on taking medicine.Comment: 39 pages, 14 figures, 13 table

Probabilistic Argumentation for Patient Decision Making

Medical drug reviews are increasingly commonplace on the web and have become an important source of information for patients undergoing medical treatment. Patients will look to these reviews in order to understand the impact the drugs have had on others who have experienced them. In short these reviews can be interpreted as a body of arguments and counterarguments for/against the drug being reviewed. One of the challenges of reading these reviews is drawing out the arguments easily and forming a final opinion; this is due to the number of reviews and the variety of arguments presented. This thesis explores the use of computational models of argumentation in order to extract structured argumentation data from the reviews and present them to the user. In particular I propose a pipeline that performs argument extraction, argument graph extraction and visualisation

Crime scripting: A systematic review

The file attached to this record is the author's final peer reviewed version.More than two decades after the publication of Cornish’s seminal work about the script-theoretic approach to crime analysis, this article examines how the concept has been applied in our community. The study provides evidence confirming that the approach is increasingly popular; and takes stock of crime scripting practices through a systematic review of over one hundred scripts published between 1994 and 2018. The results offer the first comprehensive picture of this approach, and highlights new directions for those interested in using data from cyber-systems and the Internet of Things to develop effective situational crime prevention measures

DrugExBERT for Pharmacovigilance – A Novel Approach for Detecting Drug Experiences from User-Generated Content

Pharmaceutical companies have to maintain drug safety through pharmacovigilance systems by monitoring various sources of information about adverse drug experiences. Recently, user-generated content (UGC) has emerged as a valuable source of real-world drug experiences, posing new challenges due to its high volume and variety. We present DrugExBERT, a novel approach to extract adverse drug experiences (adverse reaction, lack of effect) and supportive drug experiences (effectiveness, intervention, indication, and off-label use) from UGC. To be able to verify the extracted drug experiences, DrugExBERT additionally provides explications in the form of UGC phrases that were critical for the extraction. In our evaluation, we demonstrate that DrugExBERT outperforms state-of-the-art pharmacovigilance approaches as well as ChatGPT on several performance measures and that DrugExBERT is data- and drug-agnostic. Thus, our novel approach can help pharmaceutical companies meet their legal obligations and ethical responsibility while ensuring patient safety and monitoring drug effectiveness

Drug Reviews: Cross-condition and Cross-source Analysis by Review Quantification Using Regional CNN-LSTM Models

Pharmaceutical drugs are usually rated by customers or patients (i.e. in a scale from 1 to 10). Often, they also give reviews or comments on the drug and its side effects. It is desirable to quantify the reviews to help analyze drug favorability in the market, in the absence of ratings. Since these reviews are in the form of text, we should use lexical methods for the analysis. The intent of this study was two-fold: First, to understand how better the efficiency will be if CNN-LSTM models are used to predict ratings or sentiment from reviews. These models are known to perform better than usual machine learning models in the case of textual data sequences. Second, how effective is it to migrate such information extraction models across different drug review data sets and across different disease conditions. Therefore three experiments were designed, first, an In-domain experiment where train and test data are from the same dataset. Two more experiments were conducted to examine the migration capability of models, namely cross-data source, where train and test are from different sources and cross-disease condition model training, where train and test data belong to different disease conditions in the same dataset. The experiments were evaluated using popular metrics such as RMSE, MAE, R2 and Pearson’s coefficient and the results showed that the proposed deep learning regression model works less successfully when compared to the machine learning sentiment extraction models in the literature, which were done on the same datasets. But, this study contributes to the existing literature in the quantity of research work done and in quality of the model and also suggests the future researchers on how to improve. This work also addressed the shortcomings in the literature by introducin

CREATE: Concept Representation and Extraction from Heterogeneous Evidence

Traditional information retrieval methodology is guided by document retrieval paradigm, where relevant documents are returned in response to user queries. This paradigm faces serious drawback if the desired result is not explicitly present in a single document. The problem becomes more obvious when a user tries to obtain complete information about a real world entity, such as person, company, location etc. In such cases, various facts about the target entity or concept need to be gathered from multiple document sources. In this work, we present a method to extract information about a target entity based on the concept retrieval paradigm that focuses on extracting and blending information related to a concept from multiple sources if necessary. The paradigm is built around a generic notion of concept which is defined as any item that can be thought of as a topic of interest. Concepts may correspond to any real world entity such as restaurant, person, city, organization, etc, or any abstract item such as news topic, event, theory, etc. Web is a heterogeneous collection of data in different forms such as facts, news, opinions etc. We propose different models for different forms of data, all of which work towards the same goal of concept centric retrieval. We motivate our work based on studies about current trends and demands for information seeking. The framework helps in understanding the intent of content, i.e. opinion versus fact. Our work has been conducted on free text data in English. Nevertheless, our framework can be easily transferred to other languages

A survey on opinion summarization technique s for social media

The volume of data on the social media is huge and even keeps increasing. The need for efficient processing of this extensive information resulted in increasing research interest in knowledge engineering tasks such as Opinion Summarization. This survey shows the current opinion summarization challenges for social media, then the necessary pre-summarization steps like preprocessing, features extraction, noise elimination, and handling of synonym features. Next, it covers the various approaches used in opinion summarization like Visualization, Abstractive, Aspect based, Query-focused, Real Time, Update Summarization, and highlight other Opinion Summarization approaches such as Contrastive, Concept-based, Community Detection, Domain Specific, Bilingual, Social Bookmarking, and Social Media Sampling. It covers the different datasets used in opinion summarization and future work suggested in each technique. Finally, it provides different ways for evaluating opinion summarization