Space shuttle orbit maneuvering engine reusable thrust chamber. Task 13: Subscale helium ingestion and two dimensional heating test report

Descriptions are given of the test hardware, facility, procedures, and results of electrically heated tube, channel and panel tests conducted to determine effects of helium ingestion, two dimensional conduction, and plugged coolant channels on operating limits of convectively cooled chambers typical of space shuttle orbit maneuvering engine designs. Helium ingestion in froth form, was studied in tubular and rectangular single channel test sections. Plugged channel simulation was investigated in a three channel panel. Burn-out limits (transition of film boiling) were studied in both single channel and panel test sections to determine 2-D conduction effects as compared to tubular test results

Compression resistance of aluminium stub columns using continuous strength method

Parallel Session 4B: Stainless steel & aluminiumAluminium members are getting more popular in structural applications due to their high strength-to-weight ratio, corrosion resistance, attractive appearance, recyclability, ease of production and availability. The elastic modulus of aluminium, however, is only a third of ordinary steel, makes it vulnerable to excessive deflection. Thin sections are susceptible to local buckling at a relatively low stress and welding makes it even worse; the design stress i.e. 0.2% proof stress is almost halved in the vicinity of Heat Affected Zones (HAZ). Currently available design Codes have their guidelines both for welded and non-welded aluminium columns, which seem to produce conservative predictions for aluminium cross-sections subjected to compression. The current research aims to exploit a newly developed strain based design approach 'Continuous Strength Method (CSM)' to predict the behaviour of aluminium tubular cross-sections subjected to compression. This paper also explores the applicability of CSM to include the effects of HAZ.postprintThe 13th International Symposium on Tubular Structures (ISTS 13), Hong Kong, China, 15-17 December 2010. In Tubular structures XIII: proceedings of the 13th International Symposium on Tubular Structures, 2010, Chapter 29, p. 257-26

Spacesuit mobility knee joints

Pressure suit mobility joints are for use in interconnecting adjacent segments of an hermetically sealed spacesuit in which low torques, low leakage and a high degree of reliability are required. Each of the joints is a special purpose joint characterized by substantially constant volume and low torque characteristics and includes linkages which restrain the joint from longitudinal distension and includes a flexible, substantially impermeable diaphragm of tubular configuration spanning the distance between pivotally supported annuli. The diaphragms of selected joints include rolling convolutions for balancing the joints, while various joints include wedge-shaped sections which enhance the range of motion for the joints

Retractable tool bit having latch type catch mechanism

A retractable tool bit assembly for a tool such as an allen key is presented. The assembly includes one or more spring loaded nestable or telescoping tubular sections together with a catch mechanism for capturing and holding the tool in its retracted position. The catch mechanism consists of a latch mechanism located in a base section and which engages a conically shaped tool head located at the inner end of the tool. The tool head adjoins an eccentric oval type neck portion which extends to a rear lip of the tool head. The latch mechanism releases when the ovular neck portion rotates about the catch members upon actuation of a rotary tool drive motor. When released, all the telescoping sections and the tool extends fully outward to a use position

Thermal analysis of hollow tubular sections under high temperatures

This work presents a numerical model for thermal analysis of steel hollow tubular sections under high temperatures. Curved and straight pipes are structural tubular elements of essential application in the fluids transport, chemical processes or energy generation plants, eventually subjected at mechanical and thermal loading conditions. Hollow tubular sections may have internal voids filled with air (hollow columns, profile sections thermally insulated or steel pipes). The internal temperature should be calculated with some simplified formulas obtained from heat transfer equations. The results obtained in this work, using the internal void formulation, were compared with the thermal response from finite element formulation, for heat conduction with internal insulation and with corresponding results obtained using the simplified heat conduction equation, according Eurocode 3. For small values of the pipe thickness, the thermal behaviour may be determined with high accuracy using one-dimensional mesh approach, with axisymmetric boundary thermal conditions across section

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes

Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy. We studied the mechanism of impaired renal re-uptake of thiamine in diabetes. Expression of thiamine transporter proteins THTR-1 and THTR-2 in normal human kidney sections examined by immunohistochemistry showed intense polarised staining of the apical, luminal membranes in proximal tubules for THTR-1 and THTR-2 of the cortex and uniform, diffuse staining throughout cells of the collecting duct for THTR-1 and THTR-2 of the medulla. Human primary proximal tubule epithelial cells were incubated with low and high glucose concentration, 5 and 26 mmol/l, respectively. In high glucose concentration there was decreased expression of THTR-1 and THTR-2 (transporter mRNA: −76% and −53% respectively, p<0.001; transporter protein −77% and −83% respectively, p<0.05), concomitant with decreased expression of transcription factor specificity protein-1. High glucose concentration also produced a 37% decrease in apical to basolateral transport of thiamine transport across cell monolayers. Intensification of glycemic control corrected increased fractional excretion of thiamine in experimental diabetes. We conclude that glucose-induced decreased expression of thiamine transporters in the tubular epithelium may mediate renal mishandling of thiamine in diabetes. This is a novel mechanism of thiamine insufficiency linked to diabetic nephropathy

Calcium oxalate crystal adherence to hyaluronan-, osteopontin-, and CD44-expressing injured/regenerating tubular epithelial cells in rat kidneys

Retention of crystals in the kidney is an essential early step in renal stone formation. Studies with renal tubular cells in culture indicate that hyaluronan (HA) and osteopontin (OPN) and their mutual cell surface receptor CD44 play an important role in calcium oxalate (CaOx) crystal binding during wound healing. This concept was investigated in vivo by treating rats for 1, 4, and 8 d with ethylene glycol (0.5 and 0.75%) in their drinking water to induce renal tubular cell damage and CaOx crystalluria. Tubular injury was morphologically scored on periodic acid-Schiff-stained renal tissue sections and tissue repair assessed by immunohistochemical staining for proliferating cell nuclear antigen. CaOx crystals were visualized in periodic acid-Schiff-stained sections by polarized light microscopy, and renal calcium deposits were quantified with von Kossa staining. HA was visualized with HA-binding protein and OPN and CD44 immunohistochemically with specific antibodies and quantified with an image analyzer system. Already after 1 d of treatment, both concentrations of ethylene glycol induced hyperoxaluria and CaOx crystalluria. At this point, there was neither tubular injury nor crystal retention in the kidney, and expression of HA, OPN, and CD44 was comparable to untreated controls. After 4 and 8 d of ethylene glycol, however, intratubular crystals were found adhered to injured/regenerating (proliferating cell nuclear antigen positive) tubular epithelial cells, expressing HA, OPN, and CD44 at their luminal membrane. In conclusion, the expression of HA, OPN, and CD44 by injured/regenerating tubular cells seems to play a role in retention of crystals in the rat kidney