Modern Views of Machine Learning for Precision Psychiatry

In light of the NIMH's Research Domain Criteria (RDoC), the advent of functional neuroimaging, novel technologies and methods provide new opportunities to develop precise and personalized prognosis and diagnosis of mental disorders. Machine learning (ML) and artificial intelligence (AI) technologies are playing an increasingly critical role in the new era of precision psychiatry. Combining ML/AI with neuromodulation technologies can potentially provide explainable solutions in clinical practice and effective therapeutic treatment. Advanced wearable and mobile technologies also call for the new role of ML/AI for digital phenotyping in mobile mental health. In this review, we provide a comprehensive review of the ML methodologies and applications by combining neuroimaging, neuromodulation, and advanced mobile technologies in psychiatry practice. Additionally, we review the role of ML in molecular phenotyping and cross-species biomarker identification in precision psychiatry. We further discuss explainable AI (XAI) and causality testing in a closed-human-in-the-loop manner, and highlight the ML potential in multimedia information extraction and multimodal data fusion. Finally, we discuss conceptual and practical challenges in precision psychiatry and highlight ML opportunities in future research

Cyber–Physical–Social Frameworks for Urban Big Data Systems: A Survey

The integration of things’ data on the Web and Web linking for things’ description and discovery is leading the way towards smart Cyber–Physical Systems (CPS). The data generated in CPS represents observations gathered by sensor devices about the ambient environment that can be manipulated by computational processes of the cyber world. Alongside this, the growing use of social networks offers near real-time citizen sensing capabilities as a complementary information source. The resulting Cyber–Physical–Social System (CPSS) can help to understand the real world and provide proactive services to users. The nature of CPSS data brings new requirements and challenges to different stages of data manipulation, including identification of data sources, processing and fusion of different types and scales of data. To gain an understanding of the existing methods and techniques which can be useful for a data-oriented CPSS implementation, this paper presents a survey of the existing research and commercial solutions. We define a conceptual framework for a data-oriented CPSS and detail the various solutions for building human–machine intelligence

Employing Environmental Data and Machine Learning to Improve Mobile Health Receptivity

Behavioral intervention strategies can be enhanced by recognizing human activities using eHealth technologies. As we find after a thorough literature review, activity spotting and added insights may be used to detect daily routines inferring receptivity for mobile notifications similar to just-in-time support. Towards this end, this work develops a model, using machine learning, to analyze the motivation of digital mental health users that answer self-assessment questions in their everyday lives through an intelligent mobile application. A uniform and extensible sequence prediction model combining environmental data with everyday activities has been created and validated for proof of concept through an experiment. We find that the reported receptivity is not sequentially predictable on its own, the mean error and standard deviation are only slightly below by-chance comparison. Nevertheless, predicting the upcoming activity shows to cover about 39% of the day (up to 58% in the best case) and can be linked to user individual intervention preferences to indirectly find an opportune moment of receptivity. Therefore, we introduce an application comprising the influences of sensor data on activities and intervention thresholds, as well as allowing for preferred events on a weekly basis. As a result of combining those multiple approaches, promising avenues for innovative behavioral assessments are possible. Identifying and segmenting the appropriate set of activities is key. Consequently, deliberate and thoughtful design lays the foundation for further development within research projects by extending the activity weighting process or introducing a model reinforcement.BMBF, 13GW0157A, Verbundprojekt: Self-administered Psycho-TherApy-SystemS (SELFPASS) - Teilvorhaben: Data Analytics and Prescription for SELFPASSTU Berlin, Open-Access-Mittel - 201

Current Challenges and Barriers to the Wider Adoption of Wearable Sensor Applications and Internet-of-Things in Health and Well-being

The aim of this review is to investigate barriers and challenges of Wearable Sensors (WS) and Internet-of-Things (IoT) solutions in healthcare. This work specifically focuses on falls and Activity of Daily Life (ADLs) for ageing population and independent living for older adults. The majority of the studies focussed on the system aspects of WS and IoT solutions including advanced sensors, wireless data collection, communication platforms and usability. The current studies are focused on a single use-case/health area using non-scalable and ‘silo’ solutions. Moderate to low usability/ userfriendly approach is reported in most of the current studies. Other issues found were, inaccurate sensors, battery/power issues, restricting the users within the monitoring area/space and lack of interoperability. The advancement of wearable technology and possibilities of using advanced technology to support ageing population is a concept that has been investigated by many studies. We believe, WS and IoT monitoring plays a critical role towards support of a world-wide goal of tackling ageing population and efficient independent living. Consequently, in this study we focus on identifying three main challenges regarding data collection and processing, techniques for risk assessment, usability and acceptability of WS and IoT in wider healthcare settings