Regional science policy and the growth of knowledge megacentres in bioscience clusters

Changes in epistemology in biosciences are generating important spatial effects. The most notable of these is the emergence of a few Bioscience Megacentres of basic and applied bioscience (molecular, post-genomic, proteomics, etc.) medical and clinical research, biotechnology research, training in these and related fields, academic entrepreneurship and commercial exploitation by clusters of drug discovery start-up and spin-off companies, along with specialist venture capital and other innovation system support services. Large pharmaceutical firms that used to lead such knowledge generation and exploitation processes are becoming increasingly dependent upon innovative drug solutions produced in such clusters, and Megacentres are now the predominant source of such commercial knowledge. Big pharma is seldom at the heart of Megacentres such as those the paper will argue are found in about four locations each in the USA and Europe, but remains important for some risk capital (milestone payments), marketing and distribution of drugs discovered. The reasons for this shift (which is also spatial to some extent) are as follows: first, bioscientific research requires the formation of collaboratory relationships among hitherto cognitively dissonant disciplines molecular biology, combinatorial chemistry, high throughput screening, genomics, proteomics and bioinformatics to name a few. Second, the canonical chance discovery model of bioscientific research is being replaced by rational drug design based on those technologies because of the need massively to reduce search costs and delivery timeframes. Third, the US and to some extent European 'Crusade against Cancer' and other pathologies has seen major increases in basic research budgets (e.g. to $27.3 billion in 2003 for the US National Institutes of Health) and foundation expenditure (e.g.$1billion in 2003 by the UK's Wellcome Trust; $1 billion approximately by the top ten US medical foundations, and a comparable sum from corporate foundations). Each of these tendencies weakens the knowledge generation role of 'big pharma'and strengthens that of Megacentres. But the process also creates major, new regional disparities, which some regional governances have recognised, causing them to develop responsibilities for regional science policy and funding to offset spatial biases intrinsic in traditional national (and in the EU, supranational) research funding regimes. Responses follow a variety of models ranging from market following to both regionalised (decentralising by the centre) and regionalist (ground-up), but in each case the role of Megacentres is justified in health terms. But their role in assisting fulfilment of regional economic growth visions is also clearly perceived and pronounced in policy terms.

Supporting Youth Employment: A Guide for Community Groups

Although public money is available for education, job training and youth programs throughout the nation, many young people in low-income communities do not acquire the skills and credentials necessary to get high paying jobs. This Guide is a resource for parents, youth workers, educators and young people who want to take action. It details three major public funding sources that can support job-related training for youth: the WIA, TANF and State Education Assistance. The Guide also offers information on how to recognize effective programs, activities and supports, highlighting successful youth initiatives. A long list of youth-oriented resources is provided

Information Outlook, September 2004

Volume 8, Issue 9https://scholarworks.sjsu.edu/sla_io_2004/1008/thumbnail.jp

Information Outlook, September 2004

Volume 8, Issue 9https://scholarworks.sjsu.edu/sla_io_2004/1008/thumbnail.jp

Information Outlook, September 2004

Volume 8, Issue 9https://scholarworks.sjsu.edu/sla_io_2004/1008/thumbnail.jp

Creating a National Network of Energy Discovery-Innovation Institutes: A Step Toward America's Energy Sustainability

Draft 1.1http://deepblue.lib.umich.edu/bitstream/2027.42/88576/1/2008_NREN_Draft_1.2.pd

Energy Discovery-Innovation Institutes: A Step Toward America's Energy Sustainability

Part of the "Blueprint for American Prosperity"http://deepblue.lib.umich.edu/bitstream/2027.42/88629/1/2009_Brookings_Energy_Report.pd

Report of the 2014 NSF Cybersecurity Summit for Large Facilities and Cyberinfrastructure

This event was supported in part by the National Science Foundation under Grant Number 1234408. Any opinions, findings, and conclusions or recommendations expressed at the event or in this report are those of the authors and do not necessarily reflect the views of the National Science Foundation

Community-campus partnerships for economic development: community perspectives

Formal collaborations between community groups and academic institutions to promote economic development have increased substantially over the past 10 years. The bulk of research on community-campus partnerships has focused on the experiences of institutions of higher learning and the foundations that have funded the collaborations, leaving a gap in our understanding of community experiences. This report draws on a variety of sources, including first-person interviews and academic literature, to bring out community perspectives on what makes for successful partnerships. The conclusions are presented as practical suggestions for community groups and campuses seeking to optimize partnerships. Four case studies describe lessons learned by participating community groups.Community development ; Universities and colleges