Computer aided training in commissioning of an automated pulp distribution center

Työn tarkoituksena oli kehittää Pesmel Oy:n toimittamien järjestelmien käyttöönottokoulutusta. Kehityskohteena oli Pesmel Oy:n järjestämä automatisoidun sellunjakelukeskuksen käyttöönottokoulutus Metsä Fibre Oy:n biotuotetehtaalla Äänekoskella. Pesmel Oy:n toiveena oli saada jo olemassa olevasta koulutusmateriaalista tietokonepohjainen koulutusohjelmisto, jota voidaan hyödyntää asiakkaiden kouluttamisessa. Koulutusmateriaalin kehittämisessä päädyttiin html-pohjaiseen koulutusohjelmistoon, jossa kaikki materiaali on kerätty yhden ohjelmiston taakse. Koulutusohjelmiston kehittämisessä käytettiin hyödyksi aikaisempia tutkimuksia tietokoneavusteisen koulutusohjelman arvioinnista sekä aikaisemmista koulutusohjelmistoista, joissa on arvioitu koulutusohjelmiston suunnittelua ja laatimista. Ohjelmistosta kehitettiin sellainen, että siinä olevaa materiaalia pystytään käyttämään sekä luokkahuonekoulutuksessa, itsenäisessä opiskelussa, käyttökoulutuksessa sekä koulutuksen jälkeen koulutettujen asioiden kertaamiseen sekä korvaamaan paperinen dokumentointi. Koulutusta kehitettiin eri oppimisteorioiden pohjalta huomioiden koulutettavien tausta sekä koulutettava materiaali. Monet oppimisteoriat lähtevät siitä lähtökohdasta, että ihmiset haluavat oppia itse, joten koulutusta lähdettiin suunnittelemaan koulutettavien lähtökohdista ja tarpeista käsin. Lisäksi Pesmel Oy:n koulutusta antaville henkilöille tehtiin sähköpostikysely koulutuksen nykytilanteen ja kehityskohteiden kartoittamiseksi. Näiden pohjalta laadittiin ehdotus koulutuksen parantamiseksi. Tässä työssä esiteltyä koulutusohjelmistoa ei toistaiseksi ole päästy kokeilemaan käytännössä, joten ohjelmiston vahvuuksia ja heikkouksia arvioitiin aiempien tutkimusten valossa. Tulevaisuudessa mahdollisesti tässä pilottihankkeessa toteutettu koulutusmateriaalin ja koulutuksen kehittäminen otetaan käyttöön Metsä Fibre Oy:n biotuotetehtaan sellunjakelukeskuksessa ja pilotin onnistuessa koulutuksen kehittämishanke laajenee muihinkin projekteihin

Genetically dissecting the meiotic checkpoint active during prophase I in female mice

Females have a non-renewable number of gametes at birth. These oocytes are extremely sensitive to environmental factors that generate DNA damage. Oocyte death due to DNA damage can result in infertility and ovarian failure. In contrast to postnatal oocytes, at earlier stages of gametogenesis these cells withstand hundreds of developmentally programmed DNA breaks (DSBs). During the first meiotic division these DSBs promote synapsis (homologous chromosomes pairing), and recombination, which are both essential for sexual reproduction and environmental fitness. However, DSB repair and synapsis need to occur in a timely manner, or the quality of the gametes becomes compromised. The mechanisms that guarantee oocyte quality were hypothesized to operate through two independent pathways: one that surveys DNA integrity, and the other synapsis. However, I present experimental evidence that oocytes defective for either DNA repair or synapsis are eliminated by the same DNA damage response. Furthermore, through the detailed analysis of DNA repair dynamics, I provide evidence that the protein HORMAD2, which localizes to unsynapsed chromosomes, regulates DSB-repair. I hypothesize that HORMAD2 interferes with repair by preventing broken DNA from using the sister chromatid as a repair template. This “block to sister-chromatid repair” (BSCR) assures that the homologous chromosome is the substrate of choice. Whereas BSCR guarantees homologous recombination, it also prevents unsynapsed chromosomes from fixing DSBs. Thus, failure to synapse will result in persistent DSBs. Since DNA damage causes oocyte death postnatally, unsynapsed chromosome will trigger the DNA damage checkpoint. Through the understanding of this checkpoint, I was able to test if the transient inhibition of the DNA damage checkpoint protein (CHK2) prevents oocyte death. My finding that oocyte death was prevented, and fertility was preserved, provides evidence that chemically protecting oocyte from DNA damaging agents is a viable clinical approach. This result will hopefully translate into a treatment to delay ovarian failure. Taken together these results have implications on our current understanding of the prophase I checkpoint. TEACHING AS RESEARCH My interest in improving teaching strategies led me to research the qualitative outcome of using a novel teaching tool during the laboratory section of a histology course. I tested an interactive response system (IRS) as formative assessment tool. I found that IRS results in a positive experience, however my study was not able to detect quantitative difference on students’ grades was detected

Er e-læring riktig kurs? : hva mener de ansatte?

Masteroppgave i helse- og sosialinformatikk HSI500 - Universitetet i Agder 2017Background E-learning has become an important part of the training of employees in health organizations. Successful e-learning requires, co-operation, good interaction between educational tools, organizational culture and technology. An important precondition for achieving this good interaction is to focus on the education and organization and not so much on the technology itself. This study aims to find out what employees think and believe about e-learning. The following question is the basis for this study: «How do employees at Sørlandet Hospital HF evaluate e-learning courses, and are they likely to be positive to use e-learning courses in Læringsportalen again?» Method To answer the question, a quantitative method has been used based on a research model developed by Dr. Ming-Chi Lee at National Pingtung University in Taiwan. His research instrument was translated and used in the survey. The instrument consists of 31 statements that the respondents should consider. In addition, the respondents were asked to evaluate the e-learning course they had just completed. The questionnaire was linked to six different elearning courses in the Læringsportalen for a period of eight weeks. Result There were 115 respondents who completed the entire survey and thus form the basis for the data analysis. The findings show a general positive attitude towards e-learning both from the respondents' evaluation of the various statements and the current e-learning course. Conclusion The study shows that the research model can provide answers to the question concerning employees' attitude towards e-learning. The results and the statistical analyzes selected indicate that employees at Sørlandet Hospital HF are positive to Læringsportalen. This may imply that employees are also likely to be positive to undertake new e-learning courses. Keywords Competence, e-learning, employees, hospital, learning management system, attitude, continuance intentio