75,960 research outputs found
MedGAN: Medical Image Translation using GANs
Image-to-image translation is considered a new frontier in the field of
medical image analysis, with numerous potential applications. However, a large
portion of recent approaches offers individualized solutions based on
specialized task-specific architectures or require refinement through
non-end-to-end training. In this paper, we propose a new framework, named
MedGAN, for medical image-to-image translation which operates on the image
level in an end-to-end manner. MedGAN builds upon recent advances in the field
of generative adversarial networks (GANs) by merging the adversarial framework
with a new combination of non-adversarial losses. We utilize a discriminator
network as a trainable feature extractor which penalizes the discrepancy
between the translated medical images and the desired modalities. Moreover,
style-transfer losses are utilized to match the textures and fine-structures of
the desired target images to the translated images. Additionally, we present a
new generator architecture, titled CasNet, which enhances the sharpness of the
translated medical outputs through progressive refinement via encoder-decoder
pairs. Without any application-specific modifications, we apply MedGAN on three
different tasks: PET-CT translation, correction of MR motion artefacts and PET
image denoising. Perceptual analysis by radiologists and quantitative
evaluations illustrate that the MedGAN outperforms other existing translation
approaches.Comment: 16 pages, 8 figure
Scanner Invariant Representations for Diffusion MRI Harmonization
Purpose: In the present work we describe the correction of diffusion-weighted
MRI for site and scanner biases using a novel method based on invariant
representation.
Theory and Methods: Pooled imaging data from multiple sources are subject to
variation between the sources. Correcting for these biases has become very
important as imaging studies increase in size and multi-site cases become more
common. We propose learning an intermediate representation invariant to
site/protocol variables, a technique adapted from information theory-based
algorithmic fairness; by leveraging the data processing inequality, such a
representation can then be used to create an image reconstruction that is
uninformative of its original source, yet still faithful to underlying
structures. To implement this, we use a deep learning method based on
variational auto-encoders (VAE) to construct scanner invariant encodings of the
imaging data.
Results: To evaluate our method, we use training data from the 2018 MICCAI
Computational Diffusion MRI (CDMRI) Challenge Harmonization dataset. Our
proposed method shows improvements on independent test data relative to a
recently published baseline method on each subtask, mapping data from three
different scanning contexts to and from one separate target scanning context.
Conclusion: As imaging studies continue to grow, the use of pooled multi-site
imaging will similarly increase. Invariant representation presents a strong
candidate for the harmonization of these data
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