Random Linear Network Coding for Wireless Layered Video Broadcast: General Design Methods for Adaptive Feedback-free Transmission

This paper studies the problem of broadcasting layered video streams over heterogeneous single-hop wireless networks using feedback-free random linear network coding (RLNC). We combine RLNC with unequal error protection (UEP) and our main purpose is twofold. First, to systematically investigate the benefits of UEP+RLNC layered approach in servicing users with different reception capabilities. Second, to study the effect of not using feedback, by comparing feedback-free schemes with idealistic full-feedback schemes. To these ends, we study `expected percentage of decoded frames' as a key content-independent performance metric and propose a general framework for calculation of this metric, which can highlight the effect of key system, video and channel parameters. We study the effect of number of layers and propose a scheme that selects the optimum number of layers adaptively to achieve the highest performance. Assessing the proposed schemes with real H.264 test streams, the trade-offs among the users' performances are discussed and the gain of adaptive selection of number of layers to improve the trade-offs is shown. Furthermore, it is observed that the performance gap between the proposed feedback-free scheme and the idealistic scheme is very small and the adaptive selection of number of video layers further closes the gap.Comment: 15 pages, 12 figures, 3 tables, Under 2nd round of review, IEEE Transactions on Communication

Machine Learning and Integrative Analysis of Biomedical Big Data.

Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues