Student Affairs Division Day

Division Day is a student affairs gathering at Boston University to advance best practices in engaging students. This item contains the program schedule for this event

A Statement on Charlottesville from the Students of Color Interest Group

This article was originally published in The Prophet -- a journal created by and for the students at the Boston University School of Theology (BUSTH) to amplify the voices of STH students by promoting and sharing a range of perspectives on matters of concern including, but not limited to, spiritual practices, faith communities and society, the nature of theology, and current affairs. It serves as a platform for STH students to share their academic work, theological reflections, and life experiences with one another and the wider community."Many of us watched from afar with fear, anxiety, disgust, and anger this past weekend as white nationalists rallied in ... " [EXCERPT

Effects of Radiation on Neurite Morphology and Cytoskeleton Structure

Long-term manned space exploration to the moon, Mars, and other areas beyond Earth\u27s protective magnetic field poses possible acute and late central nervous systems (CNS) risks. Of particular concern for astronauts is exposure to high atomic number, high energy particles known as HZE particles, a component of galactic cosmic radiation (GCR). Although NASA has radiation safety requirements, the possible effects of GCR and HZE particles on the central nervous systems of astronauts remains unknown. Understanding the risks and effects of galactic cosmic radiation and HZE particles on the central nervous system will allow for safer space exploration. Additionally, and perhaps more relevant, are the effects on the CNS of patients undergoing radiation therapy for cancer treatment or for medical procedures like CT scans. Radiation (using x-rays, gamma rays, and charged particles), along with chemotherapy, is widely used to treat primary and metastatic brain tumors. Despite advances in radiation therapy, significant negative impacts on the CNS still remain. In this study, our aim was to understand the effects of x-ray radiation on neurite morphology and cytoskeleton structure using human SH-SYSY cells, a neuroblastoma cell line commonly used for neurite outgrowth studies. In addition, we monitored cytotoxicity via a metabolic proliferation assay in neuronal cells lines, as well as a primary glial cell line and glial cell line derived from a glioma. Immunocytochemistry results suggests that neurite length of differentiated SHSYSY cells decreases with increases in radiation dose and exposure time. Phase contrast microscopy results are contradictory; suggesting no significant differences between treated and control groups with regards to dose and time. Phase contrast microscopy does reveal neurite complexity decreases in differentiated SH-SYSY cells with select dosages and times of exposure. Cytotoxicity results are wildly disparate between cells lines. Data indicate radiation dose and time post-treatment affect metabolic activity. However, metabolic activity between cell lines and within a cell line can either increase or decrease in response to dose and time

Inhibiting fatty acid binding proteins decreases multiple myeloma cell proliferation and increases efficacy of dexamethasone

Multiple myeloma (MM) is an incurable cancer of the plasma cell and currently only has a 5 year survival rate of 53%. MM cells depend on a multitude of cells within the bone marrow microenvironment to flourish and resist treatment-induced cell death. Bone marrow adipocytes (BMAd), which increase in number with aging and obesity, have been shown to support myeloma cells by inducing proliferation, migration, and drug resistance, and ultimately contributing to myeloma patient relapse from remission. Herein we confirm the pro-myeloma effects of BMAd conditioned media (CM) and investigate the effects of the family of proteins termed the fatty acid binding proteins (FABPs), which are expressed both by adipocytes and tumor cells themselves. We found that high levels of FABP5 in patient myeloma cells corresponds to poor overall and relapse free survival for MM patients. Moreover, we found that pharmacologically inhibiting fatty acid binding proteins negatively impact tumor burden in vitro and in vivo,ultimately leading to increased survival of tumor-bearing mice. In addition, when combined with FABP inhibitors, dexamethasone, a common anti-myeloma treatment, has increased efficacy in vitro. Overall, these data suggest that FABPs are a novel target in myeloma and that this is a potential new cancer therapeutic target should be developed fuither

38th Chicano Commencement, 2008

38th Annual Chicano Commencement Recognizing those before us, holding the door for those who follow. = Reconociendo nuestros anteriores, y manteniendo la puerta abierta a los que siguen. The 38th Annual Chicano Commencement took place on May 25, 2008 at the Santa Clara Convention Center in Santa Clara, CA.https://scholarworks.sjsu.edu/chicanograd/1014/thumbnail.jp

Associated Students Annual Report 2014-2015

https://scholarworks.sjsu.edu/associatedstudents/1005/thumbnail.jp

Associated Students Annual Report 2015-2016

Creating Change, Broadening Perspectiveshttps://scholarworks.sjsu.edu/associatedstudents/1008/thumbnail.jp