1,330 research outputs found
Evaluating 35 Methods to Generate Structural Connectomes Using Pairwise Classification
There is no consensus on how to construct structural brain networks from
diffusion MRI. How variations in pre-processing steps affect network
reliability and its ability to distinguish subjects remains opaque. In this
work, we address this issue by comparing 35 structural connectome-building
pipelines. We vary diffusion reconstruction models, tractography algorithms and
parcellations. Next, we classify structural connectome pairs as either
belonging to the same individual or not. Connectome weights and eight
topological derivative measures form our feature set. For experiments, we use
three test-retest datasets from the Consortium for Reliability and
Reproducibility (CoRR) comprised of a total of 105 individuals. We also compare
pairwise classification results to a commonly used parametric test-retest
measure, Intraclass Correlation Coefficient (ICC).Comment: Accepted for MICCAI 2017, 8 pages, 3 figure
Disentangling causal webs in the brain using functional Magnetic Resonance Imaging: A review of current approaches
In the past two decades, functional Magnetic Resonance Imaging has been used
to relate neuronal network activity to cognitive processing and behaviour.
Recently this approach has been augmented by algorithms that allow us to infer
causal links between component populations of neuronal networks. Multiple
inference procedures have been proposed to approach this research question but
so far, each method has limitations when it comes to establishing whole-brain
connectivity patterns. In this work, we discuss eight ways to infer causality
in fMRI research: Bayesian Nets, Dynamical Causal Modelling, Granger Causality,
Likelihood Ratios, LiNGAM, Patel's Tau, Structural Equation Modelling, and
Transfer Entropy. We finish with formulating some recommendations for the
future directions in this area
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