24,363 research outputs found
Bioinformatics tools in predictive ecology: Applications to fisheries
This article is made available throught the Brunel Open Access Publishing Fund - Copygith @ 2012 Tucker et al.There has been a huge effort in the advancement of analytical techniques for molecular biological data over the past decade. This has led to many novel algorithms that are specialized to deal with data associated with biological phenomena, such as gene expression and protein interactions. In contrast, ecological data analysis has remained focused to some degree on off-the-shelf statistical techniques though this is starting to change with the adoption of state-of-the-art methods, where few assumptions can be made about the data and a more explorative approach is required, for example, through the use of Bayesian networks. In this paper, some novel bioinformatics tools for microarray data are discussed along with their ‘crossover potential’ with an application to fisheries data. In particular, a focus is made on the development of models that identify functionally equivalent species in different fish communities with the aim of predicting functional collapse
A survey of statistical network models
Networks are ubiquitous in science and have become a focal point for
discussion in everyday life. Formal statistical models for the analysis of
network data have emerged as a major topic of interest in diverse areas of
study, and most of these involve a form of graphical representation.
Probability models on graphs date back to 1959. Along with empirical studies in
social psychology and sociology from the 1960s, these early works generated an
active network community and a substantial literature in the 1970s. This effort
moved into the statistical literature in the late 1970s and 1980s, and the past
decade has seen a burgeoning network literature in statistical physics and
computer science. The growth of the World Wide Web and the emergence of online
networking communities such as Facebook, MySpace, and LinkedIn, and a host of
more specialized professional network communities has intensified interest in
the study of networks and network data. Our goal in this review is to provide
the reader with an entry point to this burgeoning literature. We begin with an
overview of the historical development of statistical network modeling and then
we introduce a number of examples that have been studied in the network
literature. Our subsequent discussion focuses on a number of prominent static
and dynamic network models and their interconnections. We emphasize formal
model descriptions, and pay special attention to the interpretation of
parameters and their estimation. We end with a description of some open
problems and challenges for machine learning and statistics.Comment: 96 pages, 14 figures, 333 reference
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A Bayesian network approach to explaining time series with changing structure
Many examples exist of multivariate time series where dependencies between variables change over time. If these changing dependencies are not taken into account, any model that is learnt from the data will average over the different dependency structures. Paradigms that try to
explain underlying processes and observed events in multivariate time series must explicitly model these changes in order to allow non-experts to
analyse and understand such data. In this paper we have developed a method for generating explanations in multivariate time series that takes into account changing dependency structure. We make use of a dynamic Bayesian network model with hidden nodes. We introduce a representa-
tion and search technique for learning such models from data and test it on synthetic time series and real-world data from an oil refinery, both of which contain changing underlying structure. We compare our method to an existing EM-based method for learning structure. Results are very promising for our method and we include sample explanations, generated from models learnt from the refinery dataset
Detectability thresholds and optimal algorithms for community structure in dynamic networks
We study the fundamental limits on learning latent community structure in
dynamic networks. Specifically, we study dynamic stochastic block models where
nodes change their community membership over time, but where edges are
generated independently at each time step. In this setting (which is a special
case of several existing models), we are able to derive the detectability
threshold exactly, as a function of the rate of change and the strength of the
communities. Below this threshold, we claim that no algorithm can identify the
communities better than chance. We then give two algorithms that are optimal in
the sense that they succeed all the way down to this limit. The first uses
belief propagation (BP), which gives asymptotically optimal accuracy, and the
second is a fast spectral clustering algorithm, based on linearizing the BP
equations. We verify our analytic and algorithmic results via numerical
simulation, and close with a brief discussion of extensions and open questions.Comment: 9 pages, 3 figure
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