Fractional dynamical model for the generation of ECG like signals from filtered coupled Van-der Pol oscillators

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.In this paper, an incommensurate fractional order (FO) model has been proposed to generate ECG like waveforms. Earlier investigation of ECG like waveform generation is based on two identical Van-der Pol (VdP) family of oscillators, which are coupled by time delays and gains. In this paper, we suitably modify the three state equations corresponding to the nonlinear cross-product of states, time delay coupling of the two oscillators and low-pass filtering, using the concept of fractional derivatives. Our results show that a wide variety of ECG like waveforms can be simulated from the proposed generalized models, characterizing heart conditions under different physiological conditions. Such generalization of the modelling of ECG waveforms may be useful to understand the physiological process behind ECG signal generation in normal and abnormal heart conditions. Along with the proposed FO models, an optimization based approach is also presented to estimate the VdP oscillator parameters for representing a realistic ECG like signal.The work presented in this paper was supported by the E.U. ARTEMIS Joint Undertaking under the Cyclic and Person-Centric Health Management: Integrated appRoach for hOme, mobile and clinical eNvironments – (CHIRON) Project, Grant Agreement # 2009-1-100228