2,090 research outputs found
Quantitative analysis by renormalized entropy of invasive electroencephalograph recordings in focal epilepsy
Invasive electroencephalograph (EEG) recordings of ten patients suffering
from focal epilepsy were analyzed using the method of renormalized entropy.
Introduced as a complexity measure for the different regimes of a dynamical
system, the feature was tested here for its spatio-temporal behavior in
epileptic seizures. In all patients a decrease of renormalized entropy within
the ictal phase of seizure was found. Furthermore, the strength of this
decrease is monotonically related to the distance of the recording location to
the focus. The results suggest that the method of renormalized entropy is a
useful procedure for clinical applications like seizure detection and
localization of epileptic foci.Comment: 10 pages, 5 figure
Mapping the epileptic brain with EEG dynamical connectivity: established methods and novel approaches
Several algorithms rooted in statistical physics, mathematics and machine learning are used to analyze neuroimaging data from patients suffering from epilepsy, with the main goals of localizing the brain region where the seizure originates from and of detecting upcoming seizure activity in order to trigger therapeutic neurostimulation devices. Some of these methods explore the dynamical connections between brain regions, exploiting the high temporal resolution of the electroencephalographic signals recorded at the scalp or directly from the cortical surface or in deeper brain areas. In this paper we describe this specific class of algorithms and their clinical application, by reviewing the state of the art and reporting their application on EEG data from an epileptic patient
Unfolding the procedure of characterizing recorded ultra low frequency, kHZ and MHz electromagetic anomalies prior to the L'Aquila earthquake as pre-seismic ones. Part I
Ultra low frequency, kHz and MHz electromagnetic anomalies were recorded
prior to the L'Aquila catastrophic earthquake that occurred on April 6, 2009.
The main aims of this contribution are: (i) To suggest a procedure for the
designation of detected EM anomalies as seismogenic ones. We do not expect to
be possible to provide a succinct and solid definition of a pre-seismic EM
emission. Instead, we attempt, through a multidisciplinary analysis, to provide
elements of a definition. (ii) To link the detected MHz and kHz EM anomalies
with equivalent last stages of the L'Aquila earthquake preparation process.
(iii) To put forward physically meaningful arguments to support a way of
quantifying the time to global failure and the identification of distinguishing
features beyond which the evolution towards global failure becomes
irreversible. The whole effort is unfolded in two consecutive parts. We clarify
we try to specify not only whether or not a single EM anomaly is pre-seismic in
itself, but mainly whether a combination of kHz, MHz, and ULF EM anomalies can
be characterized as pre-seismic one
Kullback-Leibler and Renormalized Entropy: Applications to EEGs of Epilepsy Patients
Recently, renormalized entropy was proposed as a novel measure of relative
entropy (P. Saparin et al., Chaos, Solitons & Fractals 4, 1907 (1994)) and
applied to several physiological time sequences, including EEGs of patients
with epilepsy. We show here that this measure is just a modified
Kullback-Leibler (K-L) relative entropy, and it gives similar numerical results
to the standard K-L entropy. The latter better distinguishes frequency contents
of e.g. seizure and background EEGs than renormalized entropy. We thus propose
that renormalized entropy might not be as useful as claimed by its proponents.
In passing we also make some critical remarks about the implementation of these
methods.Comment: 15 pages, 4 Postscript figures. Submitted to Phys. Rev. E, 199
An Automated System for Epilepsy Detection using EEG Brain Signals based on Deep Learning Approach
Epilepsy is a neurological disorder and for its detection, encephalography
(EEG) is a commonly used clinical approach. Manual inspection of EEG brain
signals is a time-consuming and laborious process, which puts heavy burden on
neurologists and affects their performance. Several automatic techniques have
been proposed using traditional approaches to assist neurologists in detecting
binary epilepsy scenarios e.g. seizure vs. non-seizure or normal vs. ictal.
These methods do not perform well when classifying ternary case e.g. ictal vs.
normal vs. inter-ictal; the maximum accuracy for this case by the
state-of-the-art-methods is 97+-1%. To overcome this problem, we propose a
system based on deep learning, which is an ensemble of pyramidal
one-dimensional convolutional neural network (P-1D-CNN) models. In a CNN model,
the bottleneck is the large number of learnable parameters. P-1D-CNN works on
the concept of refinement approach and it results in 60% fewer parameters
compared to traditional CNN models. Further to overcome the limitations of
small amount of data, we proposed augmentation schemes for learning P-1D-CNN
model. In almost all the cases concerning epilepsy detection, the proposed
system gives an accuracy of 99.1+-0.9% on the University of Bonn dataset.Comment: 18 page
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