Quantitative Regular Expressions for Arrhythmia Detection Algorithms

Motivated by the problem of verifying the correctness of arrhythmia-detection algorithms, we present a formalization of these algorithms in the language of Quantitative Regular Expressions. QREs are a flexible formal language for specifying complex numerical queries over data streams, with provable runtime and memory consumption guarantees. The medical-device algorithms of interest include peak detection (where a peak in a cardiac signal indicates a heartbeat) and various discriminators, each of which uses a feature of the cardiac signal to distinguish fatal from non-fatal arrhythmias. Expressing these algorithms' desired output in current temporal logics, and implementing them via monitor synthesis, is cumbersome, error-prone, computationally expensive, and sometimes infeasible. In contrast, we show that a range of peak detectors (in both the time and wavelet domains) and various discriminators at the heart of today's arrhythmia-detection devices are easily expressible in QREs. The fact that one formalism (QREs) is used to describe the desired end-to-end operation of an arrhythmia detector opens the way to formal analysis and rigorous testing of these detectors' correctness and performance. Such analysis could alleviate the regulatory burden on device developers when modifying their algorithms. The performance of the peak-detection QREs is demonstrated by running them on real patient data, on which they yield results on par with those provided by a cardiologist.Comment: CMSB 2017: 15th Conference on Computational Methods for Systems Biolog

Fluent temporal logic for discrete-time event-based models

Fluent model checking is an automated technique for verifying that an event-based operational model satisfies some state-based declarative properties. The link between the event-based and state-based formalisms is defined through fluents which are state predicates whose value are determined by the occurrences of initiating and terminating events that make the fluents values become true or false, respectively. The existing fluent temporal logic is convenient for reasoning about untimed event-based models but difficult to use for timed models. The paper extends fluent temporal logic with temporal operators for modelling timed properties of discrete-time event-based models. It presents two approaches that differ on whether the properties model the system state after the occurrence of each event or at a fixed time rate. Model checking of timed properties is made possible by translating them into the existing untimed framework. Copyright 2005 ACM

A Property Specification Pattern Catalog for Real-Time System Verification with UPPAAL

Context: The goal of specification pattern catalogs for real-time requirements is to mask the complexity of specifying such requirements in a timed temporal logic for verification. For this purpose, they provide frontends to express and translate pattern-based natural language requirements to formulae in a suitable logic. However, the widely used real-time model checking tool UPPAAL only supports a restricted subset of those formulae that focus only on basic and non-nested reachability, safety, and liveness properties. This restriction renders many specification patterns inapplicable. As a workaround, timed observer automata need to be constructed manually to express sophisticated requirements envisioned by these patterns. Objective: In this work, we fill these gaps by providing a comprehensive specification pattern catalog for UPPAAL. The catalog supports qualitative and real-time requirements and covers all corresponding patterns of existing catalogs. Method: The catalog we propose is integrated with UPPAAL. It supports the specification of qualitative and real-time requirements using patterns and provides an automated generator that translates these requirements to observer automata and TCTL formulae. The resulting artifacts are used for verifying systems in UPPAAL. Thus, our catalog enables an automated end-to-end verification process for UPPAAL based on property specification patterns and observer automata. Results: We evaluate our catalog on three UPPAAL system models reported in the literature and mostly applied in an industrial setting. As a result, not only the reproducibility of the related UPPAAL models was possible, but also the validation of an automated, seamless, and accurate pattern- and observer-based verification process. Conclusion: The proposed property specification pattern catalog for UPPAAL enables practitioners to specify qualitative and real-time requirements...Comment: Accepted Manuscrip

Model Checking Classes of Metric LTL Properties of Object-Oriented Real-Time Maude Specifications

This paper presents a transformational approach for model checking two important classes of metric temporal logic (MTL) properties, namely, bounded response and minimum separation, for nonhierarchical object-oriented Real-Time Maude specifications. We prove the correctness of our model checking algorithms, which terminate under reasonable non-Zeno-ness assumptions when the reachable state space is finite. These new model checking features have been integrated into Real-Time Maude, and are used to analyze a network of medical devices and a 4-way traffic intersection system.Comment: In Proceedings RTRTS 2010, arXiv:1009.398

Causality and Temporal Dependencies in the Design of Fault Management Systems

Reasoning about causes and effects naturally arises in the engineering of safety-critical systems. A classical example is Fault Tree Analysis, a deductive technique used for system safety assessment, whereby an undesired state is reduced to the set of its immediate causes. The design of fault management systems also requires reasoning on causality relationships. In particular, a fail-operational system needs to ensure timely detection and identification of faults, i.e. recognize the occurrence of run-time faults through their observable effects on the system. Even more complex scenarios arise when multiple faults are involved and may interact in subtle ways. In this work, we propose a formal approach to fault management for complex systems. We first introduce the notions of fault tree and minimal cut sets. We then present a formal framework for the specification and analysis of diagnosability, and for the design of fault detection and identification (FDI) components. Finally, we review recent advances in fault propagation analysis, based on the Timed Failure Propagation Graphs (TFPG) formalism.Comment: In Proceedings CREST 2017, arXiv:1710.0277

Extending the Real-Time Maude Semantics of Ptolemy to Hierarchical DE Models

This paper extends our Real-Time Maude formalization of the semantics of flat Ptolemy II discrete-event (DE) models to hierarchical models, including modal models. This is a challenging task that requires combining synchronous fixed-point computations with hierarchical structure. The synthesis of a Real-Time Maude verification model from a Ptolemy II DE model, and the formal verification of the synthesized model in Real-Time Maude, have been integrated into Ptolemy II, enabling a model-engineering process that combines the convenience of Ptolemy II DE modeling and simulation with formal verification in Real-Time Maude.Comment: In Proceedings RTRTS 2010, arXiv:1009.398