Saccadic latency in amblyopia.

We measured saccadic latencies in a large sample (total n = 459) of individuals with amblyopia or risk factors for amblyopia, e.g., strabismus or anisometropia, and normal control subjects. We presented an easily visible target randomly to the left or right, 3.5° from fixation. The interocular difference in saccadic latency is highly correlated with the interocular difference in LogMAR (Snellen) acuity-as the acuity difference increases, so does the latency difference. Strabismic and strabismic-anisometropic amblyopes have, on average, a larger difference between their eyes in LogMAR acuity than anisometropic amblyopes and thus their interocular latency difference is, on average, significantly larger than anisometropic amblyopes. Despite its relation to LogMAR acuity, the longer latency in strabismic amblyopes cannot be attributed either to poor resolution or to reduced contrast sensitivity, because their interocular differences in grating acuity and in contrast sensitivity are roughly the same as for anisometropic amblyopes. The correlation between LogMAR acuity and saccadic latency arises because of the confluence of two separable effects in the strabismic amblyopic eye-poor letter recognition impairs LogMAR acuity while an intrinsic sluggishness delays reaction time. We speculate that the frequent microsaccades and the accompanying attentional shifts, made while strabismic amblyopes struggle to maintain fixation with their amblyopic eyes, result in all types of reactions being irreducibly delayed

Do you look where I look? Attention shifts and response preparation following dynamic social cues

Studies investigating the effects of observing a gaze shift in another person often apply static images of a person with an averted gaze, while measuring response times to a peripheral target. Static images, however, are unlike how we normally perceive gaze shifts of others. Moreover, response times might only reveal the effects of a cue on covert attention and might fail to uncover cueing effects on overt attention or response preparation. We therefore extended the standard paradigm and measured cueing effects for ore realistic, dynamic cues (video clips),while comparing response times, saccade direction errors and saccade trajectories. Three cues were compared: A social cue, consisting of a eye-gaze shift, and two socially less relevant cues, consisting of a head tilting movement and a person walking past. Similar results were found for the two centrally presented cues (eye-gaze shift and head tilting) on all three response measures, suggesting that cueing is unaffected by the social status of the cue. Interestingly, the cue showing a person walking past showed a dissociation in the direction of the effects on response times on the one hand, and saccade direction errors and latencies on the other hand, suggesting the involvement of two types of (endogenous and exogenous) attention or a distinction between attention and saccadic response preparation. Our results suggest that by using dynamic cues and multiple response measures, properties of cueing can be revealed that would not be found otherwise

A retinotopic attentional trace after saccadic eye movements: evidence from event-related potentials

Saccadic eye movements are a major source of disruption to visual stability, yet we experience little of this disruption. We can keep track of the same object across multiple saccades. It is generally assumed that visual stability is due to the process of remapping, in which retinotopically organized maps are updated to compensate for the retinal shifts caused by eye movements. Recent behavioral and ERP evidence suggests that visual attention is also remapped, but that it may still leave a residual retinotopic trace immediately after a saccade. The current study was designed to further examine electrophysiological evidence for such a retinotopic trace by recording ERPs elicited by stimuli that were presented immediately after a saccade (80 msec SOA). Participants were required to maintain attention at a specific location (and to memorize this location) while making a saccadic eye movement. Immediately after the saccade, a visual stimulus was briefly presented at either the attended location (the same spatiotopic location), a location that matched the attended location retinotopically (the same retinotopic location), or one of two control locations. ERP data revealed an enhanced P1 amplitude for the stimulus presented at the retinotopically matched location, but a significant attenuation for probes presented at the original attended location. These results are consistent with the hypothesis that visuospatial attention lingers in retinotopic coordinates immediately following gaze shifts

Visual stimulation of saccades in magnetically tethered Drosophila

Flying fruit flies, Drosophila melanogaster, perform `body saccades', in which they change heading by about 90° in roughly 70 ms. In free flight, visual expansion can evoke saccades, and saccade-like turns are triggered by similar stimuli in tethered flies. However, because the fictive turns in rigidly tethered flies follow a much longer time course, the extent to which these two behaviors share a common neural basis is unknown. A key difference between tethered and free flight conditions is the presence of additional sensory cues in the latter, which might serve to modify the time course of the saccade motor program. To study the role of sensory feedback in saccades, we have developed a new preparation in which a fly is tethered to a fine steel pin that is aligned within a vertically oriented magnetic field, allowing it to rotate freely around its yaw axis. In this experimental paradigm, flies perform rapid turns averaging 35° in 80 ms, similar to the kinematics of free flight saccades. Our results indicate that tethered and free flight saccades share a common neural basis, but that the lack of appropriate feedback signals distorts the behavior performed by rigidly fixed flies. Using our new paradigm, we also investigated the features of visual stimuli that elicit saccades. Our data suggest that saccades are triggered when expanding objects reach a critical threshold size, but that their timing depends little on the precise time course of expansion. These results are consistent with expansion detection circuits studied in other insects, but do not exclude other models based on the integration of local movement detectors

Representation, space and Hollywood Squares: Looking at things that aren't there anymore

It has been argued that the human cognitive system is capable of using spatial indexes or oculomotor coordinates to relieve working memory load (Ballard, Hayhoe, Pook & Rao, 1997) track multiple moving items through occlusion (Scholl & Pylyshyn, 1999) or link incompatible cognitive and sensorimotor codes (Bridgeman and Huemer, 1998). Here we examine the use of such spatial information in memory for semantic information. Previous research has often focused on the role of task demands and the level of automaticity in the encoding of spatial location in memory tasks. We present five experiments where location is irrelevant to the task, and participants' encoding of spatial information is measured implicitly by their looking behavior during recall. In a paradigm developed from Spivey and Geng (submitted), participants were presented with pieces of auditory, semantic information as part of an event occurring in one of four regions of a computer screen. In front of a blank grid, they were asked a question relating to one of those facts. Under certain conditions it was found that during the question period participants made significantly more saccades to the empty region of space where the semantic information had been previously presented. Our findings are discussed in relation to previous research on memory and spatial location, the dorsal and ventral streams of the visual system, and the notion of a cognitive-perceptual system using spatial indexes to exploit the stability of the external world

Attentive monitoring of multiple video streams driven by a Bayesian foraging strategy

In this paper we shall consider the problem of deploying attention to subsets of the video streams for collating the most relevant data and information of interest related to a given task. We formalize this monitoring problem as a foraging problem. We propose a probabilistic framework to model observer's attentive behavior as the behavior of a forager. The forager, moment to moment, focuses its attention on the most informative stream/camera, detects interesting objects or activities, or switches to a more profitable stream. The approach proposed here is suitable to be exploited for multi-stream video summarization. Meanwhile, it can serve as a preliminary step for more sophisticated video surveillance, e.g. activity and behavior analysis. Experimental results achieved on the UCR Videoweb Activities Dataset, a publicly available dataset, are presented to illustrate the utility of the proposed technique.Comment: Accepted to IEEE Transactions on Image Processin

An fMRI study of parietal cortex involvement in the visual guidance of locomotion

Locomoting through the environment typically involves anticipating impending changes in heading trajectory in addition to maintaining the current direction of travel. We explored the neural systems involved in the “far road” and “near road” mechanisms proposed by Land and Horwood (1995) using simulated forward or backward travel where participants were required to gauge their current direction of travel (rather than directly control it). During forward egomotion, the distant road edges provided future path information, which participants used to improve their heading judgments. During backward egomotion, the road edges did not enhance performance because they no longer provided prospective information. This behavioral dissociation was reflected at the neural level, where only simulated forward travel increased activation in a region of the superior parietal lobe and the medial intraparietal sulcus. Providing only near road information during a forward heading judgment task resulted in activation in the motion complex. We propose a complementary role for the posterior parietal cortex and motion complex in detecting future path information and maintaining current lane positioning, respectively. (PsycINFO Database Record (c) 2010 APA, all rights reserved