150,512 research outputs found

    On the social induction of Alzheimer's disease: An index theorem aging model for amyloid formation

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    The central 'risk factor' for Alzheimer's disease (AD) is age. From first principles, we construct a mathematical model of protein folding and its in vivo regulation that gives this result in a natural manner. We extend the basic approach using topological information theory methods, and examine a case history of socially-induced premature aging in the United States

    Ethical sourcing : an analysis of the literature and implications for future research

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    The purpose of this study is to present a rigorous, focused review on how this field of ethical sourcing research has grown and evolved over the decades, providing implications for future research. We combine two research methodologies in this study: a systematic literature review and a citation network analysis. The former is used as a scientific tool to select the most relevant ethical sourcing articles, while the latter is then applied as a research technique to analyse these selected articles. Such a combined approach allows for a rigorous investigation into this field of research in a more scientific and objective way. Based on this approach, we identify (1) distinctive features of ethical sourcing studies such as growth trends and content issues; (2) important articles that have played a significant role in developing this field; (3) evolutionary paths that show how its knowledge has been created and transferred; (4) emerging trends that have received growing attention in the recent literature; (5) main research areas that underlie the entire ethical sourcing studies; and (6) major implications that need to be pursued in future research. The results of this study provide not only the current status of the literature but also the patters of evolution in this field of research, thus contributing to the existing literature

    Total Factor Productivity Growth and the Environment: A Case for Green Growth Accounting

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    We examine whether the use of the environment, proxied by CO2 emissions, as a factor of production contributes, in addition to con- ventional factors of production to output growth, and thus it should be accounted for in total factor productivity growth (TFPG) mea- surement and deducted from the ‘residual’. A theoretical framework of growth accounting methodology with environment as a factor of production which is unpaid in the absence of environmental policy is developed. Using data from a panel of 23 OECD countries, we show that emissions’growth have a statistically signi
cant contribution to the growth of output, that emission augmenting technical change is present along with labor augmenting technical change, and that part of output growth which is traditionally attributed to technical change should be attributed to the use of the environment as a not fully com- pensated factor of production. Our results point towards the need for developing a concept of Green Growth Accounting.Solow Residual, Total Factor Productivity Growth, Growth, Environment, Green Growth Accounting.

    Alternative model-building for the study of socially interactive robots

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    In this discussion paper, we consider the potential merits of applying an alternative approach to model building (Empirical Modelling, also known as EM) in studying social aspects of human-robot interaction (HRI). The first section of the paper considers issues in modelling for HRI. The second introduces EM principles, outlining their potential application to modelling for HRI and its implications. The final section examines the prospects for applying EM to HRI from a practical perspective with reference to a simple case study and to existing models

    Mapping, sensing and visualising the digital co-presence in the public arena

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    This paper reports on work carried out within the Cityware project using mobile technologies to map, visualise and project the digital co-presence in the city. This paper focuses on two pilot studies exploring the Bluetooth landscape in the city of Bath. Here we apply adapted and ‘digitally augmented’ methods for spatial observation and analysis based on established methods used extensively in the space syntax approach to urban design. We map the physical and digital flows at a macro level and observe static space use at the micro level. In addition we look at social and mobile behaviour from an individual’s point of view. We apply a method based on intervention through ‘Sensing and projecting’ Bluetooth names and digital identity in the public arena. We present early findings in terms of patterns of Bluetooth flow and presence, and outline initial observations about how people’s reaction towards the projection of their Bluetooth names practices in public. In particular we note the importance of constructing socially meaningful relations between people mediated by these technologies. We discuss initial results and outline issues raised in detail before finally describing ongoing work
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