Testing rTMS-Induced Neuroplasticity: A Single Case Study of Focal Hand Dystonia

Focal hand dystonia in musicians is a neurological motor disorder in which aberrant plasticity is caused by excessive repetitive use. This work's purposes were to induce plasticity changes in a dystonic musician through five daily thirty-minute sessions of 1\u2009Hz repetitive transcranial magnetic stimulation (rTMS) applied to the left M1 by using neuronavigated stimulation and to reliably measure the effect of these changes. To this aim, the relationship between neuroplasticity changes and motor recovery was investigated using fine-grained kinematic analysis. Our results suggest a statistically significant improvement in motor coordination both in a task resembling the dystonic-inducing symptoms and in a reach-to-grasp task. This single case study supports the safe and effective use of noninvasive brain stimulation in neurologic patients and highlights the importance of evaluating outcomes in measurable ways. This issue is a key aspect to focus on to classify the clinical expression of dystonia. These preliminary results promote the adoption of kinematic analysis as a valuable diagnostic tool

The selection of case studies: strategies and their applications to IS implementation case studies

Case study research by definition is well suited to the study of IS implementation, especially when context is important. Furthermore, its products are highly relevant and therefore they appeal to IS practitioners, an audience for which the IS literature has been critiqued of ignoring. While the value of single case research is methodologically viable in the study of critical cases, the multiple case study approach is believed to be more appropriate to the study of typical cases of IS implementations. However, the IS literature provides little guidance on strategies for case study selection, particularly for multiple case studies. More important, is the need to provide the rational for case selection that relates these suggested strategies to the particular objectives of the case research inquiry. The purpose of this study is to fill this gap by providing a review of strategies for single and multiple case study selection in the context of systems implementation. Furthermore, the application of these guidelines in a multiple case study of strategic decision making of enterprise systems implementations will be illustrated

Can Greater Flamingo Recognize Fertile <i>vs.</i> Infertile Egg? A Single Case Study

Fertility of captive flamingos varies between flocks, species and seasons. Individuating infertile eggs could be helpful to facilitate important decisions. Wild animals could be encouraged to abandon the nest or not, whereas in captivity removing non-viable egg would lead birds to lay a new one. The aim of this study was to investigate the parental behaviour of a pair of greater flamingos (Phoenicopterus roseus ) in the presence of a fertile and an infertile egg. Data on the posture and behaviours of the pair on the nest were collected over two different periods: first period\u2014an infertile egg was laid; second period\u2014a fertile egg was laid. For each period, 28 ten-minute sessions per flamingo partner were run. Results revealed that female flamingo spent significantly more time standing on the nest in the first than in the second period (P = 0.010). Moreover, when standing on the nest, the female performed significantly more egg-care behaviour (attention to the egg, egg rotation/moving) in the first than in the second period (P = 0.010). No significant differences between periods emerged in the male flamingo posture on the nest and behaviours. Findings from this study suggest that female flamingos stand on the nest longer if the egg is infertile, paying more attention and examining it deeply. This study provides new insights into greater flamingo parent-embryo communication. Future research is needed to improve our knowledge on this topic, as well as on the husbandry of this species in the controlled environment

Control of single-photon transport in a one-dimensional waveguide by another single photon

We study the controllable single-photon transport in a one-dimensional (1D) waveguide with nonlinear dispersion relation coupled to a three-level emitter in cascade configuration. An extra cavity field was introduced to drive one of the level transitions of the emitter. In the resonance case, when the extra cavity does not contain photons, the input single photon will be reflected, and when the cavity contains one photon, the full transmission of the input single photon can be obtained. In the off-resonance case, the single-photon transport can also be controlled by the parameters of the cavity. Therefore, we have shown that the single-photon transport can be controlled by an extra cavity field.Comment: Coments are welcome! 5 pages, 4 figure

Autotuning method for a fractional order controller for a multivariable 13C isotope separation column

The preferred controller design technique in industrial applications is based on autotuning procedures that do not involve knowledge about an actual mathematical model of the process. In this paper, a novel autotuning method for designing fractional order controllers is addressed. The proposed technique is simple and efficient. Previous research with respect to autotuning methods for fractional order controllers has considered exclusively the case of a single-input single-output process. However, in this paper, a multivariable case study is preferred. The simulation results demonstrate the validity of the design technique