61,708 research outputs found

    Special Session on Industry 4.0

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    Survey of dynamic scheduling in manufacturing systems

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    Programmable models of growth and mutation of cancer-cell populations

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    In this paper we propose a systematic approach to construct mathematical models describing populations of cancer-cells at different stages of disease development. The methodology we propose is based on stochastic Concurrent Constraint Programming, a flexible stochastic modelling language. The methodology is tested on (and partially motivated by) the study of prostate cancer. In particular, we prove how our method is suitable to systematically reconstruct different mathematical models of prostate cancer growth - together with interactions with different kinds of hormone therapy - at different levels of refinement.Comment: In Proceedings CompMod 2011, arXiv:1109.104

    An Agent-Based Approach to Self-Organized Production

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    The chapter describes the modeling of a material handling system with the production of individual units in a scheduled order. The units represent the agents in the model and are transported in the system which is abstracted as a directed graph. Since the hindrances of units on their path to the destination can lead to inefficiencies in the production, the blockages of units are to be reduced. Therefore, the units operate in the system by means of local interactions in the conveying elements and indirect interactions based on a measure of possible hindrances. If most of the units behave cooperatively ("socially"), the blockings in the system are reduced. A simulation based on the model shows the collective behavior of the units in the system. The transport processes in the simulation can be compared with the processes in a real plant, which gives conclusions about the consequencies for the production based on the superordinate planning.Comment: For related work see http://www.soms.ethz.c

    A Three-Step Methodology to Improve Domestic Energy Efficiency

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    Increasing energy prices and the greenhouse effect lead to more awareness of energy efficiency of electricity supply. During the last years, a lot of technologies have been developed to improve this efficiency. Next to large scale technologies such as windturbine parks, domestic technologies are developed. These domestic technologies can be divided in 1) Distributed Generation (DG), 2) Energy Storage and 3) Demand Side Load Management. Control algorithms optimizing a combination of these techniques can raise the energy reduction potential of the individual techniques. In this paper an overview of current research is given and a general concept is deducted. Based on this concept, a three-step optimization methodology is proposed using 1) offline local prediction, 2) offline global planning and 3) online local scheduling. The paper ends with results of simulations and field tests showing that the methodology is promising.\u
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