Multiple Instance Learning for Heterogeneous Images: Training a CNN for Histopathology

Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an image-level classification by using the quantile function. The quantile function provides a more complete description of the heterogeneity within each image, improving image-level classification. We also adapt image augmentation to the MI framework by randomly selecting cropped regions on which to apply MI aggregation during each epoch of training. This provides a mechanism to study the importance of MI learning. We validate our method on five different classification tasks for breast tumor histology and provide a visualization method for interpreting local image classifications that could lead to future insights into tumor heterogeneity

BrainFrame: A node-level heterogeneous accelerator platform for neuron simulations

Objective: The advent of High-Performance Computing (HPC) in recent years has led to its increasing use in brain study through computational models. The scale and complexity of such models are constantly increasing, leading to challenging computational requirements. Even though modern HPC platforms can often deal with such challenges, the vast diversity of the modeling field does not permit for a single acceleration (or homogeneous) platform to effectively address the complete array of modeling requirements. Approach: In this paper we propose and build BrainFrame, a heterogeneous acceleration platform, incorporating three distinct acceleration technologies, a Dataflow Engine, a Xeon Phi and a GP-GPU. The PyNN framework is also integrated into the platform. As a challenging proof of concept, we analyze the performance of BrainFrame on different instances of a state-of-the-art neuron model, modeling the Inferior- Olivary Nucleus using a biophysically-meaningful, extended Hodgkin-Huxley representation. The model instances take into account not only the neuronal- network dimensions but also different network-connectivity circumstances that can drastically change application workload characteristics. Main results: The synthetic approach of three HPC technologies demonstrated that BrainFrame is better able to cope with the modeling diversity encountered. Our performance analysis shows clearly that the model directly affect performance and all three technologies are required to cope with all the model use cases.Comment: 16 pages, 18 figures, 5 table

A C-DAG task model for scheduling complex real-time tasks on heterogeneous platforms: preemption matters

Recent commercial hardware platforms for embedded real-time systems feature heterogeneous processing units and computing accelerators on the same System-on-Chip. When designing complex real-time application for such architectures, the designer needs to make a number of difficult choices: on which processor should a certain task be implemented? Should a component be implemented in parallel or sequentially? These choices may have a great impact on feasibility, as the difference in the processor internal architectures impact on the tasks' execution time and preemption cost. To help the designer explore the wide space of design choices and tune the scheduling parameters, in this paper we propose a novel real-time application model, called C-DAG, specifically conceived for heterogeneous platforms. A C-DAG allows to specify alternative implementations of the same component of an application for different processing engines to be selected off-line, as well as conditional branches to model if-then-else statements to be selected at run-time. We also propose a schedulability analysis for the C-DAG model and a heuristic allocation algorithm so that all deadlines are respected. Our analysis takes into account the cost of preempting a task, which can be non-negligible on certain processors. We demonstrate the effectiveness of our approach on a large set of synthetic experiments by comparing with state of the art algorithms in the literature

Characterizing and Subsetting Big Data Workloads

Big data benchmark suites must include a diversity of data and workloads to be useful in fairly evaluating big data systems and architectures. However, using truly comprehensive benchmarks poses great challenges for the architecture community. First, we need to thoroughly understand the behaviors of a variety of workloads. Second, our usual simulation-based research methods become prohibitively expensive for big data. As big data is an emerging field, more and more software stacks are being proposed to facilitate the development of big data applications, which aggravates hese challenges. In this paper, we first use Principle Component Analysis (PCA) to identify the most important characteristics from 45 metrics to characterize big data workloads from BigDataBench, a comprehensive big data benchmark suite. Second, we apply a clustering technique to the principle components obtained from the PCA to investigate the similarity among big data workloads, and we verify the importance of including different software stacks for big data benchmarking. Third, we select seven representative big data workloads by removing redundant ones and release the BigDataBench simulation version, which is publicly available from http://prof.ict.ac.cn/BigDataBench/simulatorversion/.Comment: 11 pages, 6 figures, 2014 IEEE International Symposium on Workload Characterizatio

Efficient Neural Network Implementations on Parallel Embedded Platforms Applied to Real-Time Torque-Vectoring Optimization Using Predictions for Multi-Motor Electric Vehicles

The combination of machine learning and heterogeneous embedded platforms enables new potential for developing sophisticated control concepts which are applicable to the field of vehicle dynamics and ADAS. This interdisciplinary work provides enabler solutions -ultimately implementing fast predictions using neural networks (NNs) on field programmable gate arrays (FPGAs) and graphical processing units (GPUs)- while applying them to a challenging application: Torque Vectoring on a multi-electric-motor vehicle for enhanced vehicle dynamics. The foundation motivating this work is provided by discussing multiple domains of the technological context as well as the constraints related to the automotive field, which contrast with the attractiveness of exploiting the capabilities of new embedded platforms to apply advanced control algorithms for complex control problems. In this particular case we target enhanced vehicle dynamics on a multi-motor electric vehicle benefiting from the greater degrees of freedom and controllability offered by such powertrains. Considering the constraints of the application and the implications of the selected multivariable optimization challenge, we propose a NN to provide batch predictions for real-time optimization. This leads to the major contribution of this work: efficient NN implementations on two intrinsically parallel embedded platforms, a GPU and a FPGA, following an analysis of theoretical and practical implications of their different operating paradigms, in order to efficiently harness their computing potential while gaining insight into their peculiarities. The achieved results exceed the expectations and additionally provide a representative illustration of the strengths and weaknesses of each kind of platform. Consequently, having shown the applicability of the proposed solutions, this work contributes valuable enablers also for further developments following similar fundamental principles.Some of the results presented in this work are related to activities within the 3Ccar project, which has received funding from ECSEL Joint Undertaking under grant agreement No. 662192. This Joint Undertaking received support from the European Union’s Horizon 2020 research and innovation programme and Germany, Austria, Czech Republic, Romania, Belgium, United Kingdom, France, Netherlands, Latvia, Finland, Spain, Italy, Lithuania. This work was also partly supported by the project ENABLES3, which received funding from ECSEL Joint Undertaking under grant agreement No. 692455-2

Racing to hardware-validated simulation

Processor simulators rely on detailed timing models of the processor pipeline to evaluate performance. The diversity in real-world processor designs mandates building flexible simulators that expose parts of the underlying model to the user in the form of configurable parameters. Consequently, the accuracy of modeling a real processor relies on both the accuracy of the pipeline model itself, and the accuracy of adjusting the configuration parameters according to the modeled processor. Unfortunately, processor vendors publicly disclose only a subset of their design decisions, raising the probability of introducing specification inaccuracies when modeling these processors. Inaccurately tuning model parameters deviates the simulated processor from the actual one. In the worst case, using improper parameters may lead to imbalanced pipeline models compromising the simulation output. Therefore, simulation models should be hardware-validated before using them for performance evaluation. As processors increase in complexity and diversity, validating a simulator model against real hardware becomes increasingly more challenging and time-consuming. In this work, we propose a methodology for validating simulation models against real hardware. We create a framework that relies on micro-benchmarks to collect performance statistics on real hardware, and machine learning-based algorithms to fine-tune the unknown parameters based on the accumulated statistics. We overhaul the Sniper simulator to support the ARM AArch64 instruction-set architecture (ISA), and introduce two new timing models for ARM-based in-order and out-of-order cores. Using our proposed simulator validation framework, we tune the in-order and out-of-order models to match the performance of a real-world implementation of the Cortex-A53 and Cortex-A72 cores with an average error of 7% and 15%, respectively, across a set of SPEC CPU2017 benchmarks