Paper-Based Flexible Electrode Using Chemically-Modified Graphene and Functionalized Multiwalled Carbon Nanotube Composites for Electrophysiological Signal Sensing

Flexible paper-based physiological sensor electrodes were developed using chemically-modified graphene (CG) and carboxylic-functionalized multiwalled carbon nanotube composites (f@MWCNTs). A solvothermal process with additional treatment was conducted to synthesize CG and f@MWCNTs to make CG-f@MWCNT composites. The composite was sonicated in an appropriate solvent to make a uniform suspension, and then it was drop cast on a nylon membrane in a vacuum filter. A number of batches (0%~35% f@MWCNTs) were prepared to investigate the performance of the physical characteristics. The 25% f@MWCNT-loaded composite showed the best adhesion on the paper substrate. The surface topography and chemical bonding of the proposed CG-f@MWCNT electrodes were characterized by scanning electron microscopy (SEM) and Raman spectroscopy, respectively. The average sheet resistance of the 25% CG-f@MWCNT electrode was determined to be 75 Ω/⬜ , and it showed a skin contact impedance of 45.12 kΩ at 100 Hz. Electrocardiogram (ECG) signals were recorded from the chest and fingertips of healthy adults using the proposed electrodes. The CG-f@MWCNT electrodes demonstrated comfortability and a high sensitivity for electrocardiogram signal detection

Challenges in Design and Fabrication of Flexible/Stretchable Carbon- and Textile-Based Wearable Sensors for Health Monitoring: A Critical Review

To demonstrate the wearable flexible/stretchable health-monitoring sensor, it is necessary to develop advanced functional materials and fabrication technologies. Among the various developed materials and fabrication processes for wearable sensors, carbon-based materials and textile-based configurations are considered as promising approaches due to their outstanding characteristics such as high conductivity, lightweight, high mechanical properties, wearability, and biocompatibility. Despite these advantages, in order to realize practical wearable applications, electrical and mechanical performances such as sensitivity, stability, and long-term use are still not satisfied. Accordingly, in this review, we describe recent advances in process technologies to fabricate advanced carbon-based materials and textile-based sensors, followed by their applications such as human activity and electrophysiological sensors. Furthermore, we discuss the remaining challenges for both carbon- and textile-based wearable sensors and then suggest effective strategies to realize the wearable sensors in health monitoring

Smart Materials for Wearable Healthcare Devices

Wearable devices seem to have great potential that could result in a revolutionary non-clinical approach to health monitoring and diagnosing disease. With continued innovation and intensive attention to the materials and fabrication technologies, development of these healthcare devices is progressively encouraged. This chapter gives a concise review of some of the main concepts and approaches related to recent advances and developments in the scope of wearable devices from the perspective of emerging materials. A complementary section of the review linking these advanced materials with wearable device technologies is particularly specified. Some of the strong and weak points in development of each wearable material/device are clearly highlighted and criticized

Cotton fabric-based flexible electrode for electrocardiography

Early detection of heart abnormalities is one of the proposed methods to reduce number of death due to cardiovascular disease. Electrocardiography (ECG) is one of the commonly used methods in healthcare institution to monitor the heart condition. However, conventional ECG monitoring system is not suitable for longterm monitoring since it is bulky and experienced personnel is needed to interpret the ECG signal. In this study, flexible electrode and circuit using cotton fabric as the substrate material is proposed. Graphene-PEDOT:PSS ink which was synthesized via electrochemical exfoliation of graphite rod was used as the conductive material. The flexible electrode was fabricated using manual immersion of scoured fabric in the ink while wax patterning and pipetting methods were employed for fabrication of electrically conductive pattern for flexible circuit. Sheet resistance of the cotton fabric-based electrode coated with 5 layers of conductive ink is 75.9 Ω/sq. The ECG signal recorded using the cotton fabric-based electrode has similar features to that of using commercial silver/silver chloride electrode. On the other hand, the average resistance of as-fabricated 10 mm long and 1 mm wide conductive pattern is 128.68 Ω. The conductive pattern remained 42.1%, 41.1% and 53.6% of its conductance after 1000 bending cycles at bend radii of 0.50, 0.75 and 1.25 mm, respectively. Besides, the conductive pattern remained 70.4% and 50.8% of its conductance after 10 acute and obtuse folding cycles, respectively. A simple cotton fabric-based operational amplifier with gain of 1.67 was fabricated as an initial proof-of-concept for development of simple processing system on cotton fabric substrate

Wearable smart textiles for long-term electrocardiography monitoring : a review

The continuous and long-term measurement and monitoring of physiological signals such as electrocardiography (ECG) are very important for the early detection and treatment of heart disorders at an early stage prior to a serious condition occurring. The increasing demand for the continuous monitoring of the ECG signal needs the rapid development of wearable electronic technology. During wearable ECG monitoring, the electrodes are the main components that affect the signal quality and comfort of the user. This review assesses the application of textile electrodes for ECG monitoring from the fundamentals to the latest developments and prospects for their future fate. The fabrication techniques of textile electrodes and their performance in terms of skin–electrode contact impedance, motion artifacts and signal quality are also reviewed and discussed. Textile electrodes can be fabricated by integrating thin metal fiber during the manufacturing stage of textile products or by coating textiles with conductive materials like metal inks, carbon mate-rials, or conductive polymers. The review also discusses how textile electrodes for ECG function via direct skin contact or via a non-contact capacitive coupling. Finally, the current intensive and promising research towards finding textile-based ECG electrodes with better comfort and signal quality in the fields of textile, material, medical and electrical engineering are presented as a perspective

Conception, development and evaluation of polymer-based screen-printed textile electrodes for biopotential monitoring

Wearable technologies represent the new frontier of vital signs monitoring in different applications, from fitness to health. With the progressive miniaturization of the electronic components, enabling the implementation of portable and hand-held acquisition and recording devices, the research focus has shifted toward the development of effective and unobtrusive textile electrodes. This work deals with the study, development and characterization of organic-polymer-based electrodes for biopotentials. After an overview of the main materials and fabrication technologies presented so far in the scientific literature, the possibility to use these electrodes as an alternative to the Ag/AgCl disposable gelled electrodes usually adopted in clinical practice was tested. For this purpose, several textile electrode realization techniques were studied and optimized, in order to create electrodes with adequate features to detect two fundamental physiological signals: the electrocardiogram (ECG) and the electromyogram (EMG). The electrodes were obtained by depositing on the fabric the organic bio-compatible polymer poly(3,4-ethylenedioxythiophene) doped with poly(4-styrenesulfonate) (PEDOT:PSS) with three deposition procedures: dipcoating, ink-jet printing and screen printing. The physical\u2013chemical properties of the polymer solution were varied for each procedure to obtain an optimal and reproducible result. For what concerns the ECG signal, the research activity focused on screen-printed textile electrodes and their performance was first assessed by benchtop measurements and then by human trials. The first tests demonstrated that, by adding solid or liquid electrolytes the electrodes, the largest part of the characteristics required by the ANSI/AAMI EC12:2000 standard for gelled ECG electrodes can be achieved. Tests performed in different conditions showed that the skin contact impedance and the ECG morphological features are highly similar to those obtainable with disposable gelled Ag/AgCl electrodes (\u3c1 > 0.99). A trial with ten subjects revealed also the capability of the proposed electrodes to accurately capture with clinical instruments an ECG morphology with performance comparable to off-the-shelf disposable electrodes. Furthermore, the proposed textile electrodes preserve their electrical properties and functionality even after several mild washing cycles, while they suffered physical stretching. Similar tests were performed on screen-printed textile electrodes fabricated in two different sizes to test them as EMG sensors, with and without electrolytes. After a series of controlled acquisitions performed by electro-stimulating the muscles in order to analyze the waveform morphologu of the M-wave, the statistical analysis showed a high similarity in terms of rms of the noise and electrode-skin impedance between conventional and textile electrodes with the addition of solid hydrogel and saline solution. Furthermore, the M-wave recorded on the tibialis anterior muscle during the stimulation of the peroneal nerve was comparatively analyzed between conventional and textile electrodes. The comparison provided an R2 value higher than 97% in all measurement conditions. These results opened their use in smart garments for real application scenarios and for this purpose were developed a couple of smart shirts able to detect the EGC and the EMG signal. The results indicated that this approach could be adopted in the future for the development of smart garments able to comfortably detect physiological signals

Graphene textile smart clothing for wearable cardiac monitoring

Wearable electronics is a rapidly growing field that recently started to introduce successful commercial products into the consumer electronics market. Employment of biopotential signals in wearable systems as either biofeedbacks or control commands are expected to revolutionize many technologies including point of care health monitoring systems, rehabilitation devices, human–computer/machine interfaces (HCI/HMIs), and brain–computer interfaces (BCIs). Since electrodes are regarded as a decisive part of such products, they have been studied for almost a decade now, resulting in the emergence of textile electrodes. This study reports on the synthesis and application of graphene nanotextiles for the development of wearable electrocardiography (ECG) sensors for personalized health monitoring applications. In this study, we show for the first time that the electrocardiogram was successfully obtained with graphene textiles placed on a single arm. The use of only one elastic armband, and an “all-textile-approach” facilitates seamless heart monitoring with maximum comfort to the wearer. The functionality of graphene textiles produced using dip coating and stencil printing techniques has been demonstrated by the non-invasive measurement of ECG signals, up to 98% excellent correlation with conventional pre-gelled, wet, silver/silver-chloride (Ag / AgCl) electrodes. Heart rate have been successfully determined with ECG signals obtained in different situations. The system-level integration and holistic design approach presented here will be effective for developing the latest technology in wearable heart monitoring devices

Highly Sensitive Soft Foam Sensors for Wearable Applications

Due to people’s increasing desire for body health monitoring, the needs of knowing humans’ body parameters and transferring them to analyzable and understandable signals become increasingly attractive and significant. The present body-sign measurement devices are still bulky medical devices used in settings such as clinics or hospitals, which are accurate, but expensive and cannot achieve the personalization of usage targets and the monitoring of real-time body parameters. Many commercial wearable devices can provide some of the body indexes, such as the smartwatch providing the pulse/heartbeat information, but cannot give accurate and reliable data, and the data could be influenced by the user’s movement and the loose wearing habit, either. In this way, developing next-generation wearable devices combining good wearable experience and accuracy is gathering increasing attention. The aim of this study is to develop a high-performance pressure/strain sensor with the requirements of comfortable to wear, and having great electromechanical behaviour to convert the physiological signal to an analyzable signal

Wearable Sensors for Monitoring the Physiological and Biochemical Profile of the Athlete

Athletes are continually seeking new technologies and therapies to gain a competitive edge to maximize their health and performance. Athletes have gravitated toward the use of wearable sensors to monitor their training and recovery. Wearable technologies currently utilized by sports teams monitor both the internal and external workload of athletes. However, there remains an unmet medical need by the sports community to gain further insight into the internal workload of the athlete to tailor recovery protocols to each athlete. The ability to monitor biomarkers from saliva or sweat in a noninvasive and continuous manner remain the next technological gap for sports medical personnel to tailor hydration and recovery protocols per the athlete. The emergence of flexible and stretchable electronics coupled with the ability to quantify biochemical analytes and physiological parameters have enabled the detection of key markers indicative of performance and stress, as reviewed in this paper

Wearable sensors for respiration monitoring: a review

This paper provides an overview of flexible and wearable respiration sensors with emphasis on their significance in healthcare applications. The paper classifies these sensors based on their operating frequency distinguishing between high-frequency sensors, which operate above 10 MHz, and low-frequency sensors, which operate below this level. The operating principles of breathing sensors as well as the materials and fabrication techniques employed in their design are addressed. The existing research highlights the need for robust and flexible materials to enable the development of reliable and comfortable sensors. Finally, the paper presents potential research directions and proposes research challenges in the field of flexible and wearable respiration sensors. By identifying emerging trends and gaps in knowledge, this review can encourage further advancements and innovation in the rapidly evolving domain of flexible and wearable sensors.This work was supported by the Spanish Government (MICINN) under Projects TED2021-131209B-I00 and PID2021-124288OB-I00.Peer ReviewedPostprint (published version