Differentiable agent-based epidemiology

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular simulation paradigm that can represent the heterogeneity of contact interactions with granular detail and agency of individual behavior. However, conventional ABM frameworks not differentiable and present challenges in scalability; due to which it is non-trivial to connect them to auxiliary data sources. In this paper, we introduce GradABM: a scalable, differentiable design for agent-based modeling that is amenable to gradient-based learning with automatic differentiation. GradABM can quickly simulate million-size populations in few seconds on commodity hardware, integrate with deep neural networks and ingest heterogeneous data sources. This provides an array of practical benefits for calibration, forecasting, and evaluating policy interventions. We demonstrate the efficacy of GradABM via extensive experiments with real COVID-19 and influenza datasets

Scalable Approximation Algorithm for Network Immunization

The problem of identifying important players in a given network is of pivotal importance for viral marketing, public health management, network security and various other fields of social network analysis. In this work we find the most important vertices in a graph G = (V;E) to immunize so as the chances of an epidemic outbreak is minimized. This problem is directly relevant to minimizing the impact of a contagion spread (e.g. flu virus, computer virus and rumor) in a graph (e.g. social network, computer network) with a limited budget (e.g. the number of available vaccines, antivirus software, filters). It is well known that this problem is computationally intractable (it is NP-hard). In this work we reformulate the problem as a budgeted combinational optimization problem and use techniques from spectral graph theory to design an efficient greedy algorithm to find a subset of vertices to be immunized. We show that our algorithm takes less time compared to the state of the art algorithm. Thus our algorithm is scalable to networks of much larger sizes than best known solutions proposed earlier. We also give analytical bounds on the quality of our algorithm. Furthermore, we evaluate the efficacy of our algorithm on a number of real world networks and demonstrate that the empirical performance of algorithm supplements the theoretical bounds we present, both in terms of approximation guarantees and computational efficiency

Performance Evaluation of Pathfinding Algorithms

Pathfinding is the search for an optimal path from a start location to a goal location in a given environment. In Artificial Intelligence pathfinding algorithms are typically designed as a kind of graph search. These algorithms are applicable in a wide variety of applications such as computer games, robotics, networks, and navigation systems. The performance of these algorithms is affected by several factors such as the problem size, path length, the number and distribution of obstacles, data structures and heuristics. When new pathfinding algorithms are proposed in the literature, their performance is often investigated empirically (if at all). Proper experimental design and analysis is crucial to provide an informative and non- misleading evaluation. In this research, we survey many papers and classify them according to their methodology, experimental design, and analytical techniques. We identify some weaknesses in these areas that are all too frequently found in reported approaches. We first found the pitfalls in pathfinding research and then provide solutions by creating example problems. Our research shows that spurious effects, control conditions provide solutions to avoid these pitfalls