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Efficient smile detection by Extreme Learning Machine
Smile detection is a specialized task in facial expression analysis with applications such as photo selection, user experience analysis, and patient monitoring. As one of the most important and informative expressions, smile conveys the underlying emotion status such as joy, happiness, and satisfaction. In this paper, an efficient smile detection approach is proposed based on Extreme Learning Machine (ELM). The faces are first detected and a holistic flow-based face registration is applied which does not need any manual labeling or key point detection. Then ELM is used to train the classifier. The proposed smile detector is tested with different feature descriptors on publicly available databases including real-world face images. The comparisons against benchmark classifiers including Support Vector Machine (SVM) and Linear Discriminant Analysis (LDA) suggest that the proposed ELM based smile detector in general performs better and is very efficient. Compared to state-of-the-art smile detector, the proposed method achieves competitive results without preprocessing and manual registration
Machine Learning and Integrative Analysis of Biomedical Big Data.
Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues
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