Electronic health records to facilitate clinical research

Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical research. Concerns have been raised about the increasing recruitment challenges in trials, burdensome and obtrusive data collection, and uncertain generalizability of the results. Leveraging electronic health records to counterbalance these trends is an area of intense interest. The initial applications of electronic health records, as the primary data source is envisioned for observational studies, embedded pragmatic or post-marketing registry-based randomized studies, or comparative effectiveness studies. Advancing this approach to randomized clinical trials, electronic health records may potentially be used to assess study feasibility, to facilitate patient recruitment, and streamline data collection at baseline and follow-up. Ensuring data security and privacy, overcoming the challenges associated with linking diverse systems and maintaining infrastructure for repeat use of high quality data, are some of the challenges associated with using electronic health records in clinical research. Collaboration between academia, industry, regulatory bodies, policy makers, patients, and electronic health record vendors is critical for the greater use of electronic health records in clinical research. This manuscript identifies the key steps required to advance the role of electronic health records in cardiovascular clinical research

On the Convergence of Blockchain and Internet of Things (IoT) Technologies

The Internet of Things (IoT) technology will soon become an integral part of our daily lives to facilitate the control and monitoring of processes and objects and revolutionize the ways that human interacts with the physical world. For all features of IoT to become fully functional in practice, there are several obstacles on the way to be surmounted and critical challenges to be addressed. These include, but are not limited to cybersecurity, data privacy, energy consumption, and scalability. The Blockchain decentralized nature and its multi-faceted procedures offer a useful mechanism to tackle several of these IoT challenges. However, applying the Blockchain protocols to IoT without considering their tremendous computational loads, delays, and bandwidth overhead can let to a new set of problems. This review evaluates some of the main challenges we face in the integration of Blockchain and IoT technologies and provides insights and high-level solutions that can potentially handle the shortcomings and constraints of both IoT and Blockchain technologies.Comment: Includes 11 Pages, 3 Figures, To publish in Journal of Strategic Innovation and Sustainability for issue JSIS 14(1

Wearable Communications in 5G: Challenges and Enabling Technologies

As wearable devices become more ingrained in our daily lives, traditional communication networks primarily designed for human being-oriented applications are facing tremendous challenges. The upcoming 5G wireless system aims to support unprecedented high capacity, low latency, and massive connectivity. In this article, we evaluate key challenges in wearable communications. A cloud/edge communication architecture that integrates the cloud radio access network, software defined network, device to device communications, and cloud/edge technologies is presented. Computation offloading enabled by this multi-layer communications architecture can offload computation-excessive and latency-stringent applications to nearby devices through device to device communications or to nearby edge nodes through cellular or other wireless technologies. Critical issues faced by wearable communications such as short battery life, limited computing capability, and stringent latency can be greatly alleviated by this cloud/edge architecture. Together with the presented architecture, current transmission and networking technologies, including non-orthogonal multiple access, mobile edge computing, and energy harvesting, can greatly enhance the performance of wearable communication in terms of spectral efficiency, energy efficiency, latency, and connectivity.Comment: This work has been accepted by IEEE Vehicular Technology Magazin