CleverRiver: an open source and free Google Colab toolkit for deep-learning river-flow models

In a period in which climate change is significantly varying rainfall regimes and their intensity all over the world, river-flow prediction is a major concern of geosciences. In recent years there has been an increase in the use of deep-learning models for river-flow prediction. However, in this field we can observe two main issues: i) many case studies use similar (or the same) strategies without sharing the codes, and ii) the application of these techniques requires good computer knowledge. This work proposes to employ a Google Colab notebook called CleverRiver, which allows the application of deep-learning for river-flow predictions. CleverRiver is a dynamic software that can be upgraded and modified not only by the authors but also by the users. The main advantages of CleverRiver are the following: the software is not limited by the client hardware, operating systems, etc.; the code is open-source; the toolkit is integrated with user-friendly interfaces; updated releases with new architectures, data management, and model parameters will be progressively uploaded. The software consists of three sections: the first one enables to train the models by means of some architectures, parameters, and data; the second section allows to create predictions by using the trained models; the third section allows to send feedback and to share experiences with the authors, providing a flux of precious information able to improve scientific research

Genome-wide identification and prediction of SARS-CoV-2 mutations show an abundance of variants: Integrated study of bioinformatics and deep neural learning

Genomic data analysis is a fundamental system for monitoring pathogen evolution and the outbreak of infectious diseases. Based on bioinformatics and deep learning, this study was designed to identify the genomic variability of SARS-CoV-2 worldwide and predict the impending mutation rate. Analysis of 259044 SARS-CoV-2 isolates identified 3334545 mutations with an average of 14.01 mutations per isolate. Globally, single nucleotide polymorphism (SNP) is the most prevalent mutational event. The prevalence of C > T (52.67%) was noticed as a major alteration across the world followed by the G > T (14.59%) and A > G (11.13%). Strains from India showed the highest number of mutations (48) followed by Scotland, USA, Netherlands, Norway, and France having up to 36 mutations. D416G, F106F, P314L, UTR:C241T, L93L, A222V, A199A, V30L, and A220V mutations were found as the most frequent mutations. D1118H, S194L, R262H, M809L, P314L, A8D, S220G, A890D, G1433C, T1456I, R233C, F263S, L111K, A54T, A74V, L183A, A316T, V212F, L46C, V48G, Q57H, W131R, G172V, Q185H, and Y206S missense mutations were found to largely decrease the structural stability of the corresponding proteins. Conversely, D3L, L5F, and S97I were found to largely increase the structural stability of the corresponding proteins. Multi-nucleotide mutations GGG > AAC, CC > TT, TG > CA, and AT > TA have come up in our analysis which are in the top 20 mutational cohort. Future mutation rate analysis predicts a 17%, 7%, and 3% increment of C > T, A > G, and A > T, respectively in the future. Conversely, 7%, 7%, and 6% decrement is estimated for T > C, G > A, and G > T mutations, respectively. T > G\A, C > G\A, and A > T\C are not anticipated in the future. Since SARS-CoV-2 is mutating continuously, our findings will facilitate the tracking of mutations and help to map the progression of the COVID-19 intensity worldwide

Deep Learning Neural Networks Trained with MODIS Satellite-Derived Predictors for Long-Term Global Solar Radiation Prediction

Solar energy predictive models designed to emulate the long-term (e.g., monthly) global solar radiation (GSR) trained with satellite-derived predictors can be employed as decision tenets in the exploration, installation and management of solar energy production systems in remote and inaccessible solar-powered sites. In spite of a plethora of models designed for GSR prediction, deep learning, representing a state-of-the-art intelligent tool, remains an attractive approach for renewable energy exploration, monitoring and forecasting. In this paper, algorithms based on deep belief networks and deep neural networks are designed to predict long-term GSR. Deep learning algorithms trained with publicly-accessible Moderate Resolution Imaging Spectroradiometer (MODIS) satellite data are tested in Australia’s solar cities to predict the monthly GSR: single hidden layer and ensemble models. The monthly-scale MODIS-derived predictors (2003–2018) are adopted, with 15 diverse feature selection approaches including a Gaussian Emulation Machine for sensitivity analysis used to select optimal MODIS-predictor variables to simulate GSR against ground-truth values. Several statistical score metrics are adopted to comprehensively verify surface GSR simulations to ascertain the practicality of deep belief and deep neural networks. In the testing phase, deep learning models generate significantly lower absolute percentage bias (≤3%) and high Kling–Gupta efficiency (≥97.5%) values compared to the single hidden layer and ensemble model. This study ascertains that the optimal MODIS input variables employed in GSR prediction for solar energy applications can be relatively different for diverse sites, advocating a need for feature selection prior to the modelling of GSR. The proposed deep learning approach can be adopted to identify solar energy potential proactively in locations where it is impossible to install an environmental monitoring data acquisition instrument. Hence, MODIS and other related satellite-derived predictors can be incorporated for solar energy prediction as a strategy for long-term renewable energy exploration