6,165 research outputs found
Modeling Brain Circuitry over a Wide Range of Scales
If we are ever to unravel the mysteries of brain function at its most
fundamental level, we will need a precise understanding of how its component
neurons connect to each other. Electron Microscopes (EM) can now provide the
nanometer resolution that is needed to image synapses, and therefore
connections, while Light Microscopes (LM) see at the micrometer resolution
required to model the 3D structure of the dendritic network. Since both the
topology and the connection strength are integral parts of the brain's wiring
diagram, being able to combine these two modalities is critically important.
In fact, these microscopes now routinely produce high-resolution imagery in
such large quantities that the bottleneck becomes automated processing and
interpretation, which is needed for such data to be exploited to its full
potential. In this paper, we briefly review the Computer Vision techniques we
have developed at EPFL to address this need. They include delineating dendritic
arbors from LM imagery, segmenting organelles from EM, and combining the two
into a consistent representation
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M2U-net: Effective and efficient retinal vessel segmentation for real-world applications
In this paper, we present a novel neural network architecture for retinal vessel segmentation that improves over the state of the art on two benchmark datasets, is the first to run in real time on high resolution images, and its small memory and processing requirements make it deployable in mobile and embedded systems. The M2U-Net has a new encoder-decoder architecture that is inspired by the U-Net. It adds pretrained components of MobileNetV2 in the encoder part and novel contractive bottleneck blocks in the decoder part that, combined with bilinear upsampling, drastically reduce the parameter count to 0.55M compared to 31.03M in the original U-Net. We have evaluated its performance against a wide body of previously published results on three public datasets. On two of them, the M2U-Net achieves new state-of-the-art performance by a considerable margin. When implemented on a GPU, our method is the first to achieve real-time inference speeds on high-resolution fundus images. We also implemented our proposed network on an ARM-based embedded system where it segments images in between 0.6 and 15 sec, depending on the resolution. Thus, the M2U-Net enables a number of applications of retinal vessel structure extraction, such as early diagnosis of eye diseases, retinal biometric authentication systems, and robot assisted microsurgery
Deeply-Supervised CNN for Prostate Segmentation
Prostate segmentation from Magnetic Resonance (MR) images plays an important
role in image guided interven- tion. However, the lack of clear boundary
specifically at the apex and base, and huge variation of shape and texture
between the images from different patients make the task very challenging. To
overcome these problems, in this paper, we propose a deeply supervised
convolutional neural network (CNN) utilizing the convolutional information to
accurately segment the prostate from MR images. The proposed model can
effectively detect the prostate region with additional deeply supervised layers
compared with other approaches. Since some information will be abandoned after
convolution, it is necessary to pass the features extracted from early stages
to later stages. The experimental results show that significant segmentation
accuracy improvement has been achieved by our proposed method compared to other
reported approaches.Comment: Due to a crucial sign error in equation
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