2,803 research outputs found
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
MDNet: A Semantically and Visually Interpretable Medical Image Diagnosis Network
The inability to interpret the model prediction in semantically and visually
meaningful ways is a well-known shortcoming of most existing computer-aided
diagnosis methods. In this paper, we propose MDNet to establish a direct
multimodal mapping between medical images and diagnostic reports that can read
images, generate diagnostic reports, retrieve images by symptom descriptions,
and visualize attention, to provide justifications of the network diagnosis
process. MDNet includes an image model and a language model. The image model is
proposed to enhance multi-scale feature ensembles and utilization efficiency.
The language model, integrated with our improved attention mechanism, aims to
read and explore discriminative image feature descriptions from reports to
learn a direct mapping from sentence words to image pixels. The overall network
is trained end-to-end by using our developed optimization strategy. Based on a
pathology bladder cancer images and its diagnostic reports (BCIDR) dataset, we
conduct sufficient experiments to demonstrate that MDNet outperforms
comparative baselines. The proposed image model obtains state-of-the-art
performance on two CIFAR datasets as well.Comment: CVPR2017 Ora
Multimodal Machine Learning for Automated ICD Coding
This study presents a multimodal machine learning model to predict ICD-10
diagnostic codes. We developed separate machine learning models that can handle
data from different modalities, including unstructured text, semi-structured
text and structured tabular data. We further employed an ensemble method to
integrate all modality-specific models to generate ICD-10 codes. Key evidence
was also extracted to make our prediction more convincing and explainable. We
used the Medical Information Mart for Intensive Care III (MIMIC -III) dataset
to validate our approach. For ICD code prediction, our best-performing model
(micro-F1 = 0.7633, micro-AUC = 0.9541) significantly outperforms other
baseline models including TF-IDF (micro-F1 = 0.6721, micro-AUC = 0.7879) and
Text-CNN model (micro-F1 = 0.6569, micro-AUC = 0.9235). For interpretability,
our approach achieves a Jaccard Similarity Coefficient (JSC) of 0.1806 on text
data and 0.3105 on tabular data, where well-trained physicians achieve 0.2780
and 0.5002 respectively.Comment: Machine Learning for Healthcare 201
TandemNet: Distilling Knowledge from Medical Images Using Diagnostic Reports as Optional Semantic References
In this paper, we introduce the semantic knowledge of medical images from
their diagnostic reports to provide an inspirational network training and an
interpretable prediction mechanism with our proposed novel multimodal neural
network, namely TandemNet. Inside TandemNet, a language model is used to
represent report text, which cooperates with the image model in a tandem
scheme. We propose a novel dual-attention model that facilitates high-level
interactions between visual and semantic information and effectively distills
useful features for prediction. In the testing stage, TandemNet can make
accurate image prediction with an optional report text input. It also
interprets its prediction by producing attention on the image and text
informative feature pieces, and further generating diagnostic report
paragraphs. Based on a pathological bladder cancer images and their diagnostic
reports (BCIDR) dataset, sufficient experiments demonstrate that our method
effectively learns and integrates knowledge from multimodalities and obtains
significantly improved performance than comparing baselines.Comment: MICCAI2017 Ora
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