Bi-Large Neutrino Mixing See-Saw Mass Matrix with Texture Zeros and Leptogenesis

We study constraints on neutrino properties from texture zeros in bi-large mixing See-Saw mass matrix and also from leptogenesis. Texture zeros may occur in the light (class a)) or in the heavy (class b)) neutrino mass matrices. Each of these two classes has 5 different forms which can produce non-trivial three generation mixing with at least one texture zero. We find that two types of texture zero mass matrices in both class a) and class b) can be consistent with present data on neutrino masses, mixing and produce the observed baryon asymmetry of the universe. None of the neutrinos can have zero masses with the lightest of the light neutrinos having a mass larger than about 0.039 eV for class a) and 0.002 eV for class b). In these models although CKM CP violating phase vanishes, non-zero Majorana phases, however, can exist and play an important role in producing the observed baryon asymmetry in our universe through leptogenesis mechanism. The requirement of producing the observed baryon asymmetry can further distinguish different models and also restrict the See-Saw scale to be in the range $10^{12}\sim 10^{15}$ GeV.Comment: 21 pages, 7 figures revised version, some references added, to be submitted to PR

BlinkML: Efficient Maximum Likelihood Estimation with Probabilistic Guarantees

The rising volume of datasets has made training machine learning (ML) models a major computational cost in the enterprise. Given the iterative nature of model and parameter tuning, many analysts use a small sample of their entire data during their initial stage of analysis to make quick decisions (e.g., what features or hyperparameters to use) and use the entire dataset only in later stages (i.e., when they have converged to a specific model). This sampling, however, is performed in an ad-hoc fashion. Most practitioners cannot precisely capture the effect of sampling on the quality of their model, and eventually on their decision-making process during the tuning phase. Moreover, without systematic support for sampling operators, many optimizations and reuse opportunities are lost. In this paper, we introduce BlinkML, a system for fast, quality-guaranteed ML training. BlinkML allows users to make error-computation tradeoffs: instead of training a model on their full data (i.e., full model), BlinkML can quickly train an approximate model with quality guarantees using a sample. The quality guarantees ensure that, with high probability, the approximate model makes the same predictions as the full model. BlinkML currently supports any ML model that relies on maximum likelihood estimation (MLE), which includes Generalized Linear Models (e.g., linear regression, logistic regression, max entropy classifier, Poisson regression) as well as PPCA (Probabilistic Principal Component Analysis). Our experiments show that BlinkML can speed up the training of large-scale ML tasks by 6.26x-629x while guaranteeing the same predictions, with 95% probability, as the full model.Comment: 22 pages, SIGMOD 201

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)

Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely effective source control with appropriate antimicrobial therapy. Empiric antimicrobial therapy is important in the management of intra-abdominal infections and must be broad enough to cover all likely organisms because inappropriate initial antimicrobial therapy is associated with poor patient outcomes and the development of bacterial resistance. The overuse of antimicrobials is widely accepted as a major driver of some emerging infections (such as C. difficile), the selection of resistant pathogens in individual patients, and for the continued development of antimicrobial resistance globally. The growing emergence of multi-drug resistant organisms and the limited development of new agents available to counteract them have caused an impending crisis with alarming implications, especially with regards to Gram-negative bacteria. An international task force from 79 different countries has joined this project by sharing a document on the rational use of antimicrobials for patients with IAIs. The project has been termed AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections). The authors hope that AGORA, involving many of the world's leading experts, can actively raise awareness in health workers and can improve prescribing behavior in treating IAIs

LSST Science Book, Version 2.0

A survey that can cover the sky in optical bands over wide fields to faint magnitudes with a fast cadence will enable many of the exciting science opportunities of the next decade. The Large Synoptic Survey Telescope (LSST) will have an effective aperture of 6.7 meters and an imaging camera with field of view of 9.6 deg^2, and will be devoted to a ten-year imaging survey over 20,000 deg^2 south of +15 deg. Each pointing will be imaged 2000 times with fifteen second exposures in six broad bands from 0.35 to 1.1 microns, to a total point-source depth of r~27.5. The LSST Science Book describes the basic parameters of the LSST hardware, software, and observing plans. The book discusses educational and outreach opportunities, then goes on to describe a broad range of science that LSST will revolutionize: mapping the inner and outer Solar System, stellar populations in the Milky Way and nearby galaxies, the structure of the Milky Way disk and halo and other objects in the Local Volume, transient and variable objects both at low and high redshift, and the properties of normal and active galaxies at low and high redshift. It then turns to far-field cosmological topics, exploring properties of supernovae to z~1, strong and weak lensing, the large-scale distribution of galaxies and baryon oscillations, and how these different probes may be combined to constrain cosmological models and the physics of dark energy.Comment: 596 pages. Also available at full resolution at http://www.lsst.org/lsst/sciboo

B-physics computations from Nf=2 tmQCD

We present an accurate lattice QCD computation of the b-quark mass, the B and Bs decay constants, the B-mixing bag-parameters for the full four-fermion operator basis, as well as estimates for \xi and f_{Bq}\sqrt{B_q} extrapolated to the continuum limit and the physical pion mass. We have used Nf = 2 dynamical quark gauge configurations at four values of the lattice spacing generated by ETMC. Extrapolation in the heavy quark mass from the charm to the bottom quark region has been carried out using ratios of physical quantities computed at nearby quark masses, having an exactly known infinite mass limit.Comment: 7 pages, 4 figures, presented at the 31st International Symposium on Lattice Field Theory (Lattice 2013), 29 July - 3 August 2013, Mainz, German

Observing the sky at extremely high energies with the Cherenkov Telescope Array: Status of the GCT project

The Cherenkov Telescope Array is the main global project of ground-based gamma-ray astronomy for the coming decades. Performance will be significantly improved relative to present instruments, allowing a new insight into the high-energy Universe [1]. The nominal CTA southern array will include a sub-array of seventy 4 m telescopes spread over a few square kilometers to study the sky at extremely high energies, with the opening of a new window in the multi-TeV energy range. The Gamma-ray Cherenkov Telescope (GCT) is one of the proposed telescope designs for that sub-array. The GCT prototype recorded its first Cherenkov light on sky in 2015. After an assessment phase in 2016, new observations have been performed successfully in 2017. The GCT collaboration plans to install its first telescopes and cameras on the CTA site in Chile in 2018-2019 and to contribute a number of telescopes to the subsequent CTA production phase.Comment: 8 pages, 7 figures, ICRC201

GALEX J201337.6+092801: The lowest gravity subdwarf B pulsator

We present the recent discovery of a new subdwarf B variable (sdBV), with an exceptionally low surface gravity. Our spectroscopy of J20136+0928 places it at Teff = 32100 +/- 500, log(g) = 5.15 +/- 0.10, and log(He/H) = -2.8 +/- 0.1. With a magnitude of B = 12.0, it is the second brightest V361 Hya star ever found. Photometry from three different observatories reveals a temporal spectrum with eleven clearly detected periods in the range 376 to 566 s, and at least five more close to our detection limit. These periods are unusually long for the V361 Hya class of short-period sdBV pulsators, but not unreasonable for p- and g-modes close to the radial fundamental, given its low surface gravity. Of the ~50 short period sdB pulsators known to date, only a single one has been found to have comparable spectroscopic parameters to J20136+0928. This is the enigmatic high-amplitude pulsator V338 Ser, and we conclude that J20136+0928 is the second example of this rare subclass of sdB pulsators located well above the canonical extreme horizontal branch in the HR diagram.Comment: 5 pages, accepted for publication in ApJ Letter

X-ray spectral complexity in narrow-line Seyfert 1 galaxies

We present a systematic analysis of the X-ray spectral properties of a sample of 22 ``narrow-line'' Seyfert 1 galaxies for which data are available from the ASCA public archive. Many of these sources, which were selected on the basis of their relatively narrow H-beta line width (FWHM <= 2000 km/s), show significant spectral complexity in the X-ray band. Their measured hard power-law continua have photon indices spanning the range 1.6 - 2.5 with a mean of 2.1, which is only slightly steeper than the norm for ``broad-line'' Seyfert 1s. All but four of the sources exhibit a soft excess, which can be modelled as blackbody emission (T_{bb} ~ 100 - 300 eV) superposed on the underlying power-law. This soft component is often so strong that, even in the relatively hard bandpass of ASCA, it contains a significant fraction, if not the bulk, of the X-ray luminosity, apparently ruling out models in which the soft excess is produced entirely through reprocessing of the hard continuum. Most notably, 6 of the 22 objects show evidence for a broad absorption feature centred in the energy range 1.1 - 1.4 keV, which could be the signature of resonance absorption in highly ionized material. A further 3 sources exhibit ``warm absorption'' edges in the 0.7 - 0.9 keV bandpass. Remarkably, all 9 ``absorbed'' sources have H-beta line widths below 1000 km/s, which is less than the median value for the sample taken as a whole. This tendency for very narrow line widths to correlate with the presence of ionized absorption features in the soft X-ray spectra of NLS1s, if confirmed in larger samples, may provide a further clue in the puzzle of active galactic nuclei.Comment: 13 pages, 5 figures, accepted for publication in MNRA

On the intersection of free subgroups in free products of groups

Let (G_i | i in I) be a family of groups, let F be a free group, and let G = F *(*I G_i), the free product of F and all the G_i. Let FF denote the set of all finitely generated subgroups H of G which have the property that, for each g in G and each i in I, H \cap G_i^{g} = {1}. By the Kurosh Subgroup Theorem, every element of FF is a free group. For each free group H, the reduced rank of H is defined as r(H) = max{rank(H) -1, 0} in \naturals \cup {\infty} \subseteq [0,\infty]. To avoid the vacuous case, we make the additional assumption that FF contains a non-cyclic group, and we define sigma := sup{r(H\cap K)/(r(H)r(K)) : H, K in FF and r(H)r(K) \ne 0}, sigma in [1,\infty]. We are interested in precise bounds for sigma. In the special case where I is empty, Hanna Neumann proved that sigma in [1,2], and conjectured that sigma = 1; almost fifty years later, this interval has not been reduced. With the understanding that \infty/(\infty -2) = 1, we define theta := max{|L|/(|L|-2) : L is a subgroup of G and |L| > 2}, theta in [1,3]. Generalizing Hanna Neumann's theorem, we prove that sigma in [theta, 2 theta], and, moreover, sigma = 2 theta if G has 2-torsion. Since sigma is finite, FF is closed under finite intersections. Generalizing Hanna Neumann's conjecture, we conjecture that sigma = theta whenever G does not have 2-torsion.Comment: 28 pages, no figure

Region-wide temporal and spatial variation in Caribbean reef architecture: is coral cover the whole story?

The architectural complexity of coral reefs is largely generated by reef-building corals, yet the effects of current regional-scale declines in coral cover on reef complexity are poorly understood. In particular, both the extent to which declines in coral cover lead to declines in complexity and the length of time it takes for reefs to collapse following coral mortality are unknown. Here we assess the extent of temporal and spatial covariation between coral cover and reef architectural complexity using a Caribbean-wide dataset of temporally replicated estimates spanning four decades. Both coral cover and architectural complexity have declined rapidly over time, with little evidence of a time-lag. However, annual rates of change in coral cover and complexity do not covary, and levels of complexity vary greatly among reefs with similar coral cover. These findings suggest that the stressors influencing Caribbean reefs are sufficiently severe and widespread to produce similar regional-scale declines in coral cover and reef complexity, even though reef architectural complexity is not a direct function of coral cover at local scales. Given that architectural complexity is not a simple function of coral cover, it is important that conservation monitoring and restoration give due consideration to both architecture and coral cover. This will help ensure that the ecosystem services supported by architectural complexity, such as nutrient recycling, dissipation of wave energy, fish production and diversity, are maintained and enhanced