2 research outputs found
In-Vitro MPI-Guided IVOCT Catheter Tracking in Real Time for Motion Artifact Compensation
Purpose: Using 4D magnetic particle imaging (MPI), intravascular optical
coherence tomography (IVOCT) catheters are tracked in real time in order to
compensate for image artifacts related to relative motion. Our approach
demonstrates the feasibility for bimodal IVOCT and MPI in-vitro experiments.
Material and Methods: During IVOCT imaging of a stenosis phantom the catheter
is tracked using MPI. A 4D trajectory of the catheter tip is determined from
the MPI data using center of mass sub-voxel strategies. A custom built IVOCT
imaging adapter is used to perform different catheter motion profiles: no
motion artifacts, motion artifacts due to catheter bending, and heart beat
motion artifacts. Two IVOCT volume reconstruction methods are compared
qualitatively and quantitatively using the DICE metric and the known stenosis
length. Results: The MPI-tracked trajectory of the IVOCT catheter is validated
in multiple repeated measurements calculating the absolute mean error and
standard deviation. Both volume reconstruction methods are compared and
analyzed whether they are capable of compensating the motion artifacts. The
novel approach of MPI-guided catheter tracking corrects motion artifacts
leading to a DICE coefficient with a minimum of 86% in comparison to 58% for a
standard reconstruction approach. Conclusions: IVOCT catheter tracking with MPI
in real time is an auspicious method for radiation free MPI-guided IVOCT
interventions. The combination of MPI and IVOCT can help to reduce motion
artifacts due to catheter bending and heart beat for optimized IVOCT volume
reconstructions.Comment: 19 pages, 11 figure