Convolutional Sparse Kernel Network for Unsupervised Medical Image Analysis

The availability of large-scale annotated image datasets and recent advances in supervised deep learning methods enable the end-to-end derivation of representative image features that can impact a variety of image analysis problems. Such supervised approaches, however, are difficult to implement in the medical domain where large volumes of labelled data are difficult to obtain due to the complexity of manual annotation and inter- and intra-observer variability in label assignment. We propose a new convolutional sparse kernel network (CSKN), which is a hierarchical unsupervised feature learning framework that addresses the challenge of learning representative visual features in medical image analysis domains where there is a lack of annotated training data. Our framework has three contributions: (i) We extend kernel learning to identify and represent invariant features across image sub-patches in an unsupervised manner. (ii) We initialise our kernel learning with a layer-wise pre-training scheme that leverages the sparsity inherent in medical images to extract initial discriminative features. (iii) We adapt a multi-scale spatial pyramid pooling (SPP) framework to capture subtle geometric differences between learned visual features. We evaluated our framework in medical image retrieval and classification on three public datasets. Our results show that our CSKN had better accuracy when compared to other conventional unsupervised methods and comparable accuracy to methods that used state-of-the-art supervised convolutional neural networks (CNNs). Our findings indicate that our unsupervised CSKN provides an opportunity to leverage unannotated big data in medical imaging repositories.Comment: Accepted by Medical Image Analysis (with a new title 'Convolutional Sparse Kernel Network for Unsupervised Medical Image Analysis'). The manuscript is available from following link (https://doi.org/10.1016/j.media.2019.06.005

Cross-convolutional-layer Pooling for Image Recognition

Recent studies have shown that a Deep Convolutional Neural Network (DCNN) pretrained on a large image dataset can be used as a universal image descriptor, and that doing so leads to impressive performance for a variety of image classification tasks. Most of these studies adopt activations from a single DCNN layer, usually the fully-connected layer, as the image representation. In this paper, we proposed a novel way to extract image representations from two consecutive convolutional layers: one layer is utilized for local feature extraction and the other serves as guidance to pool the extracted features. By taking different viewpoints of convolutional layers, we further develop two schemes to realize this idea. The first one directly uses convolutional layers from a DCNN. The second one applies the pretrained CNN on densely sampled image regions and treats the fully-connected activations of each image region as convolutional feature activations. We then train another convolutional layer on top of that as the pooling-guidance convolutional layer. By applying our method to three popular visual classification tasks, we find our first scheme tends to perform better on the applications which need strong discrimination on subtle object patterns within small regions while the latter excels in the cases that require discrimination on category-level patterns. Overall, the proposed method achieves superior performance over existing ways of extracting image representations from a DCNN.Comment: Fixed typos. Journal extension of arXiv:1411.7466. Accepted to IEEE Transactions on Pattern Analysis and Machine Intelligenc

Deformable Part Models are Convolutional Neural Networks

Deformable part models (DPMs) and convolutional neural networks (CNNs) are two widely used tools for visual recognition. They are typically viewed as distinct approaches: DPMs are graphical models (Markov random fields), while CNNs are "black-box" non-linear classifiers. In this paper, we show that a DPM can be formulated as a CNN, thus providing a novel synthesis of the two ideas. Our construction involves unrolling the DPM inference algorithm and mapping each step to an equivalent (and at times novel) CNN layer. From this perspective, it becomes natural to replace the standard image features used in DPM with a learned feature extractor. We call the resulting model DeepPyramid DPM and experimentally validate it on PASCAL VOC. DeepPyramid DPM significantly outperforms DPMs based on histograms of oriented gradients features (HOG) and slightly outperforms a comparable version of the recently introduced R-CNN detection system, while running an order of magnitude faster

Spatial Pyramid Pooling in Deep Convolutional Networks for Visual Recognition

Existing deep convolutional neural networks (CNNs) require a fixed-size (e.g., 224x224) input image. This requirement is "artificial" and may reduce the recognition accuracy for the images or sub-images of an arbitrary size/scale. In this work, we equip the networks with another pooling strategy, "spatial pyramid pooling", to eliminate the above requirement. The new network structure, called SPP-net, can generate a fixed-length representation regardless of image size/scale. Pyramid pooling is also robust to object deformations. With these advantages, SPP-net should in general improve all CNN-based image classification methods. On the ImageNet 2012 dataset, we demonstrate that SPP-net boosts the accuracy of a variety of CNN architectures despite their different designs. On the Pascal VOC 2007 and Caltech101 datasets, SPP-net achieves state-of-the-art classification results using a single full-image representation and no fine-tuning. The power of SPP-net is also significant in object detection. Using SPP-net, we compute the feature maps from the entire image only once, and then pool features in arbitrary regions (sub-images) to generate fixed-length representations for training the detectors. This method avoids repeatedly computing the convolutional features. In processing test images, our method is 24-102x faster than the R-CNN method, while achieving better or comparable accuracy on Pascal VOC 2007. In ImageNet Large Scale Visual Recognition Challenge (ILSVRC) 2014, our methods rank #2 in object detection and #3 in image classification among all 38 teams. This manuscript also introduces the improvement made for this competition.Comment: This manuscript is the accepted version for IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI) 2015. See Changelo