Information retrieval and text mining technologies for chemistry

Efficient access to chemical information contained in scientific literature, patents, technical reports, or the web is a pressing need shared by researchers and patent attorneys from different chemical disciplines. Retrieval of important chemical information in most cases starts with finding relevant documents for a particular chemical compound or family. Targeted retrieval of chemical documents is closely connected to the automatic recognition of chemical entities in the text, which commonly involves the extraction of the entire list of chemicals mentioned in a document, including any associated information. In this Review, we provide a comprehensive and in-depth description of fundamental concepts, technical implementations, and current technologies for meeting these information demands. A strong focus is placed on community challenges addressing systems performance, more particularly CHEMDNER and CHEMDNER patents tasks of BioCreative IV and V, respectively. Considering the growing interest in the construction of automatically annotated chemical knowledge bases that integrate chemical information and biological data, cheminformatics approaches for mapping the extracted chemical names into chemical structures and their subsequent annotation together with text mining applications for linking chemistry with biological information are also presented. Finally, future trends and current challenges are highlighted as a roadmap proposal for research in this emerging field.A.V. and M.K. acknowledge funding from the European Community’s Horizon 2020 Program (project reference: 654021 - OpenMinted). M.K. additionally acknowledges the Encomienda MINETAD-CNIO as part of the Plan for the Advancement of Language Technology. O.R. and J.O. thank the Foundation for Applied Medical Research (FIMA), University of Navarra (Pamplona, Spain). This work was partially funded by Consellería de Cultura, Educación e Ordenación Universitaria (Xunta de Galicia), and FEDER (European Union), and the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684). We thank Iñigo Garciá -Yoldi for useful feedback and discussions during the preparation of the manuscript.info:eu-repo/semantics/publishedVersio

Exploiting general-purpose background knowledge for automated schema matching

The schema matching task is an integral part of the data integration process. It is usually the first step in integrating data. Schema matching is typically very complex and time-consuming. It is, therefore, to the largest part, carried out by humans. One reason for the low amount of automation is the fact that schemas are often defined with deep background knowledge that is not itself present within the schemas. Overcoming the problem of missing background knowledge is a core challenge in automating the data integration process. In this dissertation, the task of matching semantic models, so-called ontologies, with the help of external background knowledge is investigated in-depth in Part I. Throughout this thesis, the focus lies on large, general-purpose resources since domain-specific resources are rarely available for most domains. Besides new knowledge resources, this thesis also explores new strategies to exploit such resources. A technical base for the development and comparison of matching systems is presented in Part II. The framework introduced here allows for simple and modularized matcher development (with background knowledge sources) and for extensive evaluations of matching systems. One of the largest structured sources for general-purpose background knowledge are knowledge graphs which have grown significantly in size in recent years. However, exploiting such graphs is not trivial. In Part III, knowledge graph em- beddings are explored, analyzed, and compared. Multiple improvements to existing approaches are presented. In Part IV, numerous concrete matching systems which exploit general-purpose background knowledge are presented. Furthermore, exploitation strategies and resources are analyzed and compared. This dissertation closes with a perspective on real-world applications

Annual Report of the University, 2005-2006, Volumes 1-7

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