3 research outputs found
Privacy in the Genomic Era
Genome sequencing technology has advanced at a rapid pace and it is now
possible to generate highly-detailed genotypes inexpensively. The collection
and analysis of such data has the potential to support various applications,
including personalized medical services. While the benefits of the genomics
revolution are trumpeted by the biomedical community, the increased
availability of such data has major implications for personal privacy; notably
because the genome has certain essential features, which include (but are not
limited to) (i) an association with traits and certain diseases, (ii)
identification capability (e.g., forensics), and (iii) revelation of family
relationships. Moreover, direct-to-consumer DNA testing increases the
likelihood that genome data will be made available in less regulated
environments, such as the Internet and for-profit companies. The problem of
genome data privacy thus resides at the crossroads of computer science,
medicine, and public policy. While the computer scientists have addressed data
privacy for various data types, there has been less attention dedicated to
genomic data. Thus, the goal of this paper is to provide a systematization of
knowledge for the computer science community. In doing so, we address some of
the (sometimes erroneous) beliefs of this field and we report on a survey we
conducted about genome data privacy with biomedical specialists. Then, after
characterizing the genome privacy problem, we review the state-of-the-art
regarding privacy attacks on genomic data and strategies for mitigating such
attacks, as well as contextualizing these attacks from the perspective of
medicine and public policy. This paper concludes with an enumeration of the
challenges for genome data privacy and presents a framework to systematize the
analysis of threats and the design of countermeasures as the field moves
forward
Controlled Functional Encryption
3École polytechnique fédérale de Lausanne Motivated by privacy and usability requirements in various sce-narios where existing cryptographic tools (like secure multi-party computation and functional encryption) are not adequate, we in-troduce a new cryptographic tool called Controlled Functional En-cryption (C-FE). As in functional encryption, C-FE allows a user (client) to learn only certain functions of encrypted data, using keys obtained from an authority. However, we allow (and require) the client to send a fresh key request to the authority every time it wants to evaluate a function on a ciphertext. We obtain efficient solu-tions by carefully combining CCA2 secure public-key encryption (or rerandomizable RCCA secure public-key encryption, depend-ing on the nature of security desired) with Yao’s garbled circuit. Our main contributions in this work include developing and for-mally defining the notion of C-FE; designing theoretical and prac-tical constructions of C-FE schemes achieving these definitions for specific and general classes of functions; and evaluating the perfor-mance of our constructions on various application scenarios