137 research outputs found

    An Examination of the Impact of COVID-19 on the Job Satisfaction and Emotional Well-Being of ICU Nurses

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    Healthcare systems have been demonstrably altered because of the COVID-19 pandemic. Resources were stretched and patient conditions deteriorated on a scale previously unseen, leaving nurses at the forefront to face the adversities brought about by the pandemic. In this study, a questionnaire was utilized to better understand how COVID-19 has impacted the stress level, resilience/well-being, moral distress, job satisfaction/enjoyment, practice environment, and intent to remain in the nursing profession of nursing alums from East Tennessee State University. This study focused on a subset of nurses working in critical care, to consider the impact that the pandemic had on ICU nurses’ emotional well-being and job enjoyment. This study collected general demographics and information regarding how each participant’s work was impacted as a result of COVID-19. The Practice Environment Scale of the Nursing Work Index (PES-NWI) questionnaire, Job Enjoyment Scale (JES), and Professional Quality of Life (Pro-QOL) scales were also leveraged to gain an understanding of the participants’ perspectives on their work and mental situations. The results showed that critical nurses generally answered more negatively on the PES-NWI, JES, and ProQOL scales. The study concludes that ICU nurses have lower emotional well-being and job enjoyment than nurses in general and may have been more greatly impacted by the COVID-19 pandemic

    Towards Genetic Identification with Male-specific Mutations

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    The identification and application of new genetic variants for differentiation patrilineally related male relatives using Y chromosomal short tandem repeats (Y-STRs)

    Functional Foods and their Implications for Health Promotion

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    Functional Foods and Their Implications for Health Promotion presents functional foods, from raw ingredients to the final product, providing a detailed explanation on how these foods work and an overview of their impact on health. The book presents the functions of food against disease and discusses how healthier foods can be produced. Broken into four parts, the book presents a deep dive into plant-derived functional foods, dairy foods, marine food and beverages. The book includes case studies, applications, literature reviews and coverage of recent developments. Intended for nutritionists, dieticians, food technologists, as well as students and researchers working in nutrition, dietetics, and food science, this book is sure to be a welcomed resource

    Non-coding RNAs in ovine immunity: Identification of unannotated genes and functional analyses of high throughput genomic data

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    210 p.Non-coding RNAs (ncRNAs) are involved in several biological processes in mammals, including the immune system response to pathogens and vaccines. The annotation and functional characterization of two of the main classes of ncRNAs, microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), is more advanced in humans than in livestock species, and thus, there is limited knowledge about the function of these transcripts. The main objective of this work was the identification of ovine non-coding genes, concretely miRNA and lncRNA genes, that are involved in the innate and adaptive immune responses induced by vaccines, vaccine components and pathogen infections. For this purpose, high-throughput transcriptome sequencing datasets produced for this purpose and datasets publicly available were analysed with bioinformatic tools and workflows in order to identify unannotated non-coding genes, profile their expression in different tissues and perform evolutionary conservation analyses. More than 12000 unannotated ovine lncRNAs and 1000 ovine miRNAs were identified in the different analyses, with varying levels of sequence conservation. Differential expression analyses between unstimulated samples and samples stimulated with pathogen infection or vaccination resulted in hundreds of lncRNAs and miRNAs with changed expression. Gene co-expression analyses revealed immune gene-enriched clusters associated with immune system activation. These genes make up a prioritized set of potential candidates for deeper experimental analyses. Taken together, these results should help completing the sheep non-coding gene catalogue, and most importantly, they give evidence of immune state-specific ncRNA expression patterns in a livestock species

    Towards Genetic Identification with Male-specific Mutations

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    Neues aus Wissenschaft und Lehre

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    Das Jahrbuch der Heinrich-Heine-Universität Düsseldorf versteht sich als Forum für den wissenschaftlichen Dialog der Universität zu Zeitfragen, zu aktuellen Problemlagen und Herausforderungen von Wissenschaft und Gesellschaft, als Brücke der Vermittlung zwischen Forschung und Öffentlichkeit sowie als Gedächtnisort der Innovationen und des Fortschritts in Forschung und Lehre der Universität und als Speicher der wissenschafts- und hochschulpolitischen Entscheidungen für strukturelle Weichenstellungen mit Langzeitwirkung. Zielgruppe ist die an den Arbeitsergebnissen in Forschung und Lehre sowie an wissenschaftlichen Entscheidungen der Heinrich-Heine-Universität interessierte Öffentlichkeit. Diese soll über die Dynamik und das sich wandelnde Profil der Fakultäten kontinuierlich informiert und in die Lage versetzt werden, sich intensiver mit neuen Forschungsfragen und -ergebnissen auseinander zu setzen. Es geht vor allem darum, die Be-deutung der Forschung für die verschiedenen Lebensbereiche und damit auch für unsere gesellschaftliche Entwicklung bewusst zu machen. Die Beiträge vermitteln gleichsam als Momentaufnahme einen Ausschnitt aus dem permanenten Prozess des sich verändernden Profils der Fakultäten. Erst eine Folge von Jahrbüchern eröffnet die Chance, die Tiefe des Gesamtprofils auszuloten und dessen Nachhaltigkeit zu erkennen

    Single Cell Approach Towards Immune Signaling Dynamics

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    Molecular Phylogenetics and Mitochondrial Evolution

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    The aim of the present Special Issue is to address the state-of-art of mitochondrial genomics and phylogenomics. Mitochondrial markers are widespread in phylogenetics; however, it is becoming increasingly clear that (i) many discordance issues arise with respect to nuclear markers and (ii) many features that are normally considered 'typical' for the mitochondrial genome are indeed highly unstable and unconserved

    Superfluid Optomechanics with Nanofluidic Geometries

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    Town of Raymond, New Hampshire 2021 annual report.

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    This is an annual report containing vital statistics for a town/city in the state of New Hampshire
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