Harvesting Multiple Views for Marker-less 3D Human Pose Annotations

Recent advances with Convolutional Networks (ConvNets) have shifted the bottleneck for many computer vision tasks to annotated data collection. In this paper, we present a geometry-driven approach to automatically collect annotations for human pose prediction tasks. Starting from a generic ConvNet for 2D human pose, and assuming a multi-view setup, we describe an automatic way to collect accurate 3D human pose annotations. We capitalize on constraints offered by the 3D geometry of the camera setup and the 3D structure of the human body to probabilistically combine per view 2D ConvNet predictions into a globally optimal 3D pose. This 3D pose is used as the basis for harvesting annotations. The benefit of the annotations produced automatically with our approach is demonstrated in two challenging settings: (i) fine-tuning a generic ConvNet-based 2D pose predictor to capture the discriminative aspects of a subject's appearance (i.e.,"personalization"), and (ii) training a ConvNet from scratch for single view 3D human pose prediction without leveraging 3D pose groundtruth. The proposed multi-view pose estimator achieves state-of-the-art results on standard benchmarks, demonstrating the effectiveness of our method in exploiting the available multi-view information.Comment: CVPR 2017 Camera Read

Prospects for Theranostics in Neurosurgical Imaging: Empowering Confocal Laser Endomicroscopy Diagnostics via Deep Learning

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence imaging technology that has the potential to increase intraoperative precision, extend resection, and tailor surgery for malignant invasive brain tumors because of its subcellular dimension resolution. Despite its promising diagnostic potential, interpreting the gray tone fluorescence images can be difficult for untrained users. In this review, we provide a detailed description of bioinformatical analysis methodology of CLE images that begins to assist the neurosurgeon and pathologist to rapidly connect on-the-fly intraoperative imaging, pathology, and surgical observation into a conclusionary system within the concept of theranostics. We present an overview and discuss deep learning models for automatic detection of the diagnostic CLE images and discuss various training regimes and ensemble modeling effect on the power of deep learning predictive models. Two major approaches reviewed in this paper include the models that can automatically classify CLE images into diagnostic/nondiagnostic, glioma/nonglioma, tumor/injury/normal categories and models that can localize histological features on the CLE images using weakly supervised methods. We also briefly review advances in the deep learning approaches used for CLE image analysis in other organs. Significant advances in speed and precision of automated diagnostic frame selection would augment the diagnostic potential of CLE, improve operative workflow and integration into brain tumor surgery. Such technology and bioinformatics analytics lend themselves to improved precision, personalization, and theranostics in brain tumor treatment.Comment: See the final version published in Frontiers in Oncology here: https://www.frontiersin.org/articles/10.3389/fonc.2018.00240/ful