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Computational Strategies for Scalable Genomics Analysis.
The revolution in next-generation DNA sequencing technologies is leading to explosive data growth in genomics, posing a significant challenge to the computing infrastructure and software algorithms for genomics analysis. Various big data technologies have been explored to scale up/out current bioinformatics solutions to mine the big genomics data. In this review, we survey some of these exciting developments in the applications of parallel distributed computing and special hardware to genomics. We comment on the pros and cons of each strategy in the context of ease of development, robustness, scalability, and efficiency. Although this review is written for an audience from the genomics and bioinformatics fields, it may also be informative for the audience of computer science with interests in genomics applications
ViZDoom Competitions: Playing Doom from Pixels
This paper presents the first two editions of Visual Doom AI Competition,
held in 2016 and 2017. The challenge was to create bots that compete in a
multi-player deathmatch in a first-person shooter (FPS) game, Doom. The bots
had to make their decisions based solely on visual information, i.e., a raw
screen buffer. To play well, the bots needed to understand their surroundings,
navigate, explore, and handle the opponents at the same time. These aspects,
together with the competitive multi-agent aspect of the game, make the
competition a unique platform for evaluating the state of the art reinforcement
learning algorithms. The paper discusses the rules, solutions, results, and
statistics that give insight into the agents' behaviors. Best-performing agents
are described in more detail. The results of the competition lead to the
conclusion that, although reinforcement learning can produce capable Doom bots,
they still are not yet able to successfully compete against humans in this
game. The paper also revisits the ViZDoom environment, which is a flexible,
easy to use, and efficient 3D platform for research for vision-based
reinforcement learning, based on a well-recognized first-person perspective
game Doom
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