30,191 research outputs found
NiftyNet: a deep-learning platform for medical imaging
Medical image analysis and computer-assisted intervention problems are
increasingly being addressed with deep-learning-based solutions. Established
deep-learning platforms are flexible but do not provide specific functionality
for medical image analysis and adapting them for this application requires
substantial implementation effort. Thus, there has been substantial duplication
of effort and incompatible infrastructure developed across many research
groups. This work presents the open-source NiftyNet platform for deep learning
in medical imaging. The ambition of NiftyNet is to accelerate and simplify the
development of these solutions, and to provide a common mechanism for
disseminating research outputs for the community to use, adapt and build upon.
NiftyNet provides a modular deep-learning pipeline for a range of medical
imaging applications including segmentation, regression, image generation and
representation learning applications. Components of the NiftyNet pipeline
including data loading, data augmentation, network architectures, loss
functions and evaluation metrics are tailored to, and take advantage of, the
idiosyncracies of medical image analysis and computer-assisted intervention.
NiftyNet is built on TensorFlow and supports TensorBoard visualization of 2D
and 3D images and computational graphs by default.
We present 3 illustrative medical image analysis applications built using
NiftyNet: (1) segmentation of multiple abdominal organs from computed
tomography; (2) image regression to predict computed tomography attenuation
maps from brain magnetic resonance images; and (3) generation of simulated
ultrasound images for specified anatomical poses.
NiftyNet enables researchers to rapidly develop and distribute deep learning
solutions for segmentation, regression, image generation and representation
learning applications, or extend the platform to new applications.Comment: Wenqi Li and Eli Gibson contributed equally to this work. M. Jorge
Cardoso and Tom Vercauteren contributed equally to this work. 26 pages, 6
figures; Update includes additional applications, updated author list and
formatting for journal submissio
Neuroconductor: an R platform for medical imaging analysis
Neuroconductor (https://neuroconductor.org) is an open-source platform for rapid testing and dissemination of reproducible computational imaging software. The goals of the project are to: (i) provide a centralized repository of R software dedicated to image analysis, (ii) disseminate software updates quickly, (iii) train a large, diverse community of scientists using detailed tutorials and short courses, (iv) increase software quality via automatic and manual quality controls, and (v) promote reproducibility of image data analysis. Based on the programming language R (https://www.r-project.org/), Neuroconductor starts with 51 inter-operable packages that cover multiple areas of imaging including visualization, data processing and storage, and statistical inference. Neuroconductor accepts new R package submissions, which are subject to a formal review and continuous automated testing. We provide a description of the purpose of Neuroconductor and the user and developer experience
MITK-ModelFit: A generic open-source framework for model fits and their exploration in medical imaging -- design, implementation and application on the example of DCE-MRI
Many medical imaging techniques utilize fitting approaches for quantitative
parameter estimation and analysis. Common examples are pharmacokinetic modeling
in DCE MRI/CT, ADC calculations and IVIM modeling in diffusion-weighted MRI and
Z-spectra analysis in chemical exchange saturation transfer MRI. Most available
software tools are limited to a special purpose and do not allow for own
developments and extensions. Furthermore, they are mostly designed as
stand-alone solutions using external frameworks and thus cannot be easily
incorporated natively in the analysis workflow. We present a framework for
medical image fitting tasks that is included in MITK, following a rigorous
open-source, well-integrated and operating system independent policy. Software
engineering-wise, the local models, the fitting infrastructure and the results
representation are abstracted and thus can be easily adapted to any model
fitting task on image data, independent of image modality or model. Several
ready-to-use libraries for model fitting and use-cases, including fit
evaluation and visualization, were implemented. Their embedding into MITK
allows for easy data loading, pre- and post-processing and thus a natural
inclusion of model fitting into an overarching workflow. As an example, we
present a comprehensive set of plug-ins for the analysis of DCE MRI data, which
we validated on existing and novel digital phantoms, yielding competitive
deviations between fit and ground truth. Providing a very flexible environment,
our software mainly addresses developers of medical imaging software that
includes model fitting algorithms and tools. Additionally, the framework is of
high interest to users in the domain of perfusion MRI, as it offers
feature-rich, freely available, validated tools to perform pharmacokinetic
analysis on DCE MRI data, with both interactive and automatized batch
processing workflows.Comment: 31 pages, 11 figures URL: http://mitk.org/wiki/MITK-ModelFi
SlicerAstro: a 3-D interactive visual analytics tool for HI data
SKA precursors are capable of detecting hundreds of galaxies in HI in a
single 12 hours pointing. In deeper surveys one will probe more easily faint HI
structures, typically located in the vicinity of galaxies, such as tails,
filaments, and extraplanar gas. The importance of interactive visualization has
proven to be fundamental for the exploration of such data as it helps users to
receive immediate feedback when manipulating the data. We have developed
SlicerAstro, a 3-D interactive viewer with new analysis capabilities, based on
traditional 2-D input/output hardware. These capabilities enhance the data
inspection, allowing faster analysis of complex sources than with traditional
tools. SlicerAstro is an open-source extension of 3DSlicer, a multi-platform
open source software package for visualization and medical image processing.
We demonstrate the capabilities of the current stable binary release of
SlicerAstro, which offers the following features: i) handling of FITS files and
astronomical coordinate systems; ii) coupled 2-D/3-D visualization; iii)
interactive filtering; iv) interactive 3-D masking; v) and interactive 3-D
modeling. In addition, SlicerAstro has been designed with a strong, stable and
modular C++ core, and its classes are also accessible via Python scripting,
allowing great flexibility for user-customized visualization and analysis
tasks.Comment: 18 pages, 11 figures, Accepted by Astronomy and Computing.
SlicerAstro link: https://github.com/Punzo/SlicerAstro/wiki#get-slicerastr
NEFI: Network Extraction From Images
Networks and network-like structures are amongst the central building blocks
of many technological and biological systems. Given a mathematical graph
representation of a network, methods from graph theory enable a precise
investigation of its properties. Software for the analysis of graphs is widely
available and has been applied to graphs describing large scale networks such
as social networks, protein-interaction networks, etc. In these applications,
graph acquisition, i.e., the extraction of a mathematical graph from a network,
is relatively simple. However, for many network-like structures, e.g. leaf
venations, slime molds and mud cracks, data collection relies on images where
graph extraction requires domain-specific solutions or even manual. Here we
introduce Network Extraction From Images, NEFI, a software tool that
automatically extracts accurate graphs from images of a wide range of networks
originating in various domains. While there is previous work on graph
extraction from images, theoretical results are fully accessible only to an
expert audience and ready-to-use implementations for non-experts are rarely
available or insufficiently documented. NEFI provides a novel platform allowing
practitioners from many disciplines to easily extract graph representations
from images by supplying flexible tools from image processing, computer vision
and graph theory bundled in a convenient package. Thus, NEFI constitutes a
scalable alternative to tedious and error-prone manual graph extraction and
special purpose tools. We anticipate NEFI to enable the collection of larger
datasets by reducing the time spent on graph extraction. The analysis of these
new datasets may open up the possibility to gain new insights into the
structure and function of various types of networks. NEFI is open source and
available http://nefi.mpi-inf.mpg.de
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Collaborative analysis of multi-gigapixel imaging data using Cytomine
Motivation: Collaborative analysis of massive imaging datasets is essential to enable scientific discoveries.
Results: We developed Cytomine to foster active and distributed collaboration of multidisciplinary teams for large-scale image-based studies. It uses web development methodologies and machine learning in order to readily organize, explore, share and analyze (semantically and quantitatively) multi-gigapixel imaging data over the internet. We illustrate how it has been used in several biomedical applications
Using CamiTK for rapid prototyping of interactive Computer Assisted Medical Intervention applications
Computer Assisted Medical Intervention (CAMI hereafter) is a complex
multi-disciplinary field. CAMI research requires the collaboration of experts
in several fields as diverse as medicine, computer science, mathematics,
instrumentation, signal processing, mechanics, modeling, automatics, optics,
etc
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