Data-driven modelling of biological multi-scale processes

Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales. In this manuscript we review mathematical modelling approaches used to describe the individual spatial scales and how they are integrated into holistic models. We discuss the relation between spatial and temporal scales and the implication of that on multi-scale modelling. Based upon this overview over state-of-the-art modelling approaches, we formulate key challenges in mathematical and computational modelling of biological multi-scale and multi-physics processes. In particular, we considered the availability of analysis tools for multi-scale models and model-based multi-scale data integration. We provide a compact review of methods for model-based data integration and model-based hypothesis testing. Furthermore, novel approaches and recent trends are discussed, including computation time reduction using reduced order and surrogate models, which contribute to the solution of inference problems. We conclude the manuscript by providing a few ideas for the development of tailored multi-scale inference methods.Comment: This manuscript will appear in the Journal of Coupled Systems and Multiscale Dynamics (American Scientific Publishers

Supplementary report to the final report of the coral reef expert group: S8. Monitoring site planner - choosing where to monitor coral reefs on the Great Barrier Reef

[Extract] In this project we develop a multi-criteria analysis and optimisation tool, called the Monitoring Site Planner, to assist in the evaluation of the existing and new proposed coral reef monitoring programs for the Great Barrier Reef (the Reef). This tool allows the performance of a given monitoring survey design (a set of reefs that will be monitored) to be evaluated against a set of performance criteria. This tool can be run as an interactive web application that is available for use from https://tools.eatlas.org.au/msp.An accessible copy of this report is not yet available from this repository, please contact [email protected] for more information

State-of-the-art in aerodynamic shape optimisation methods

Aerodynamic optimisation has become an indispensable component for any aerodynamic design over the past 60 years, with applications to aircraft, cars, trains, bridges, wind turbines, internal pipe flows, and cavities, among others, and is thus relevant in many facets of technology. With advancements in computational power, automated design optimisation procedures have become more competent, however, there is an ambiguity and bias throughout the literature with regards to relative performance of optimisation architectures and employed algorithms. This paper provides a well-balanced critical review of the dominant optimisation approaches that have been integrated with aerodynamic theory for the purpose of shape optimisation. A total of 229 papers, published in more than 120 journals and conference proceedings, have been classified into 6 different optimisation algorithm approaches. The material cited includes some of the most well-established authors and publications in the field of aerodynamic optimisation. This paper aims to eliminate bias toward certain algorithms by analysing the limitations, drawbacks, and the benefits of the most utilised optimisation approaches. This review provides comprehensive but straightforward insight for non-specialists and reference detailing the current state for specialist practitioners

Enhancing remanufacturing automation using deep learning approach

In recent years, remanufacturing has significant interest from researchers and practitioners to improve efficiency through maximum value recovery of products at end-of-life (EoL). It is a process of returning used products, known as EoL products, to as-new condition with matching or higher warranty than the new products. However, these remanufacturing processes are complex and time-consuming to implement manually, causing reduced productivity and posing dangers to personnel. These challenges require automating the various remanufacturing process stages to achieve higher throughput, reduced lead time, cost and environmental impact while maximising economic gains. Besides, as highlighted by various research groups, there is currently a shortage of adequate remanufacturing-specific technologies to achieve full automation. -- This research explores automating remanufacturing processes to improve competitiveness by analysing and developing deep learning-based models for automating different stages of the remanufacturing processes. Analysing deep learning algorithms represents a viable option to investigate and develop technologies with capabilities to overcome the outlined challenges. Deep learning involves using artificial neural networks to learn high-level abstractions in data. Deep learning (DL) models are inspired by human brains and have produced state-of-the-art results in pattern recognition, object detection and other applications. The research further investigates the empirical data of torque converter components recorded from a remanufacturing facility in Glasgow, UK, using the in-case and cross-case analysis to evaluate the remanufacturing inspection, sorting, and process control applications. -- Nevertheless, the developed algorithm helped capture, pre-process, train, deploy and evaluate the performance of the respective processes. The experimental evaluation of the in-case and cross-case analysis using model prediction accuracy, misclassification rate, and model loss highlights that the developed models achieved a high prediction accuracy of above 99.9% across the sorting, inspection and process control applications. Furthermore, a low model loss between 3x10-3 and 1.3x10-5 was obtained alongside a misclassification rate that lies between 0.01% to 0.08% across the three applications investigated, thereby highlighting the capability of the developed deep learning algorithms to perform the sorting, process control and inspection in remanufacturing. The results demonstrate the viability of adopting deep learning-based algorithms in automating remanufacturing processes, achieving safer and more efficient remanufacturing. -- Finally, this research is unique because it is the first to investigate using deep learning and qualitative torque-converter image data for modelling remanufacturing sorting, inspection and process control applications. It also delivers a custom computational model that has the potential to enhance remanufacturing automation when utilised. The findings and publications also benefit both academics and industrial practitioners. Furthermore, the model is easily adaptable to other remanufacturing applications with minor modifications to enhance process efficiency in today's workplaces.In recent years, remanufacturing has significant interest from researchers and practitioners to improve efficiency through maximum value recovery of products at end-of-life (EoL). It is a process of returning used products, known as EoL products, to as-new condition with matching or higher warranty than the new products. However, these remanufacturing processes are complex and time-consuming to implement manually, causing reduced productivity and posing dangers to personnel. These challenges require automating the various remanufacturing process stages to achieve higher throughput, reduced lead time, cost and environmental impact while maximising economic gains. Besides, as highlighted by various research groups, there is currently a shortage of adequate remanufacturing-specific technologies to achieve full automation. -- This research explores automating remanufacturing processes to improve competitiveness by analysing and developing deep learning-based models for automating different stages of the remanufacturing processes. Analysing deep learning algorithms represents a viable option to investigate and develop technologies with capabilities to overcome the outlined challenges. Deep learning involves using artificial neural networks to learn high-level abstractions in data. Deep learning (DL) models are inspired by human brains and have produced state-of-the-art results in pattern recognition, object detection and other applications. The research further investigates the empirical data of torque converter components recorded from a remanufacturing facility in Glasgow, UK, using the in-case and cross-case analysis to evaluate the remanufacturing inspection, sorting, and process control applications. -- Nevertheless, the developed algorithm helped capture, pre-process, train, deploy and evaluate the performance of the respective processes. The experimental evaluation of the in-case and cross-case analysis using model prediction accuracy, misclassification rate, and model loss highlights that the developed models achieved a high prediction accuracy of above 99.9% across the sorting, inspection and process control applications. Furthermore, a low model loss between 3x10-3 and 1.3x10-5 was obtained alongside a misclassification rate that lies between 0.01% to 0.08% across the three applications investigated, thereby highlighting the capability of the developed deep learning algorithms to perform the sorting, process control and inspection in remanufacturing. The results demonstrate the viability of adopting deep learning-based algorithms in automating remanufacturing processes, achieving safer and more efficient remanufacturing. -- Finally, this research is unique because it is the first to investigate using deep learning and qualitative torque-converter image data for modelling remanufacturing sorting, inspection and process control applications. It also delivers a custom computational model that has the potential to enhance remanufacturing automation when utilised. The findings and publications also benefit both academics and industrial practitioners. Furthermore, the model is easily adaptable to other remanufacturing applications with minor modifications to enhance process efficiency in today's workplaces