2,491 research outputs found

    An embodied approach to informational interventions: using conceptual metaphors to promote sustainable healthy diets

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    Poor diet quality and environmental degradation are two major challenges of our times. Unhealthy and unsustainable dietary practices, such as the overconsumption of meat and consumer food waste behaviour, contribute greatly to both issues. Across seventeen online and field experiments, in two different cultures (US and China), this thesis investigates if the embodied cognition approach, and more specifically, research on conceptual metaphors, can be used to develop interventions to promote sustainable healthy diets. Interventions relying on conceptual metaphors have been shown to stimulate attitudinal and behavioural changes in other fields (e.g., marketing and political communications), but are rarely adopted to encourage sustainable healthy diets. To fill in this gap in the literature, I conducted five sets of experimental studies examining the effects of different metaphors on specific sustainable healthy dietary practices, each of which forms an independent empirical paper (Chapters 2-6 of the thesis). After introducing the current perspectives on embodied cognition and conceptual metaphors in the context of this research (Chapter 1), Chapter 2 looks into the conceptual metaphor “Healthy is Up”, demonstrating that US people implicitly associate healthiness with verticality, and offering recommendations for healthy eating guidelines. Chapter 3 extends this research to Chinese samples and partially replicates the results. Chapter 4 shows that the anthropomorphic metaphor “Animals are Friends” discourages meat consumption by inducing anticipatory guilt among US omnivores, whereas Chapter 5 reveals that Chinese omnivores are more responsive to another anthropomorphic metaphor, namely, “Animals are Family”. Bringing lab insights 6 to the real world, Chapter 6 demonstrates with a longitudinal field experiment that anthropomorphic metaphors together with environmental feedback result in a higher reduction in food waste as compared to other feedback interventions. The strengths, limitations and implications of those empirical papers are discussed in the conclusive part of the thesis

    Analysis and monitoring of single HaCaT cells using volumetric Raman mapping and machine learning

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    No explorer reached a pole without a map, no chef served a meal without tasting, and no surgeon implants untested devices. Higher accuracy maps, more sensitive taste buds, and more rigorous tests increase confidence in positive outcomes. Biomedical manufacturing necessitates rigour, whether developing drugs or creating bioengineered tissues [1]–[4]. By designing a dynamic environment that supports mammalian cells during experiments within a Raman spectroscope, this project provides a platform that more closely replicates in vivo conditions. The platform also adds the opportunity to automate the adaptation of the cell culture environment, alongside spectral monitoring of cells with machine learning and three-dimensional Raman mapping, called volumetric Raman mapping (VRM). Previous research highlighted key areas for refinement, like a structured approach for shading Raman maps [5], [6], and the collection of VRM [7]. Refining VRM shading and collection was the initial focus, k-means directed shading for vibrational spectroscopy map shading was developed in Chapter 3 and exploration of depth distortion and VRM calibration (Chapter 4). “Cage” scaffolds, designed using the findings from Chapter 4 were then utilised to influence cell behaviour by varying the number of cage beams to change the scaffold porosity. Altering the porosity facilitated spectroscopy investigation into previously observed changes in cell biology alteration in response to porous scaffolds [8]. VRM visualised changed single human keratinocyte (HaCaT) cell morphology, providing a complementary technique for machine learning classification. Increased technical rigour justified progression onto in-situ flow chamber for Raman spectroscopy development in Chapter 6, using a Psoriasis (dithranol-HaCaT) model on unfixed cells. K-means-directed shading and principal component analysis (PCA) revealed HaCaT cell adaptations aligning with previous publications [5] and earlier thesis sections. The k-means-directed Raman maps and PCA score plots verified the drug-supplying capacity of the flow chamber, justifying future investigation into VRM and machine learning for monitoring single cells within the flow chamber

    Classical and quantum algorithms for scaling problems

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    This thesis is concerned with scaling problems, which have a plethora of connections to different areas of mathematics, physics and computer science. Although many structural aspects of these problems are understood by now, we only know how to solve them efficiently in special cases.We give new algorithms for non-commutative scaling problems with complexity guarantees that match the prior state of the art. To this end, we extend the well-known (self-concordance based) interior-point method (IPM) framework to Riemannian manifolds, motivated by its success in the commutative setting. Moreover, the IPM framework does not obviously suffer from the same obstructions to efficiency as previous methods. It also yields the first high-precision algorithms for other natural geometric problems in non-positive curvature.For the (commutative) problems of matrix scaling and balancing, we show that quantum algorithms can outperform the (already very efficient) state-of-the-art classical algorithms. Their time complexity can be sublinear in the input size; in certain parameter regimes they are also optimal, whereas in others we show no quantum speedup over the classical methods is possible. Along the way, we provide improvements over the long-standing state of the art for searching for all marked elements in a list, and computing the sum of a list of numbers.We identify a new application in the context of tensor networks for quantum many-body physics. We define a computable canonical form for uniform projected entangled pair states (as the solution to a scaling problem), circumventing previously known undecidability results. We also show, by characterizing the invariant polynomials, that the canonical form is determined by evaluating the tensor network contractions on networks of bounded size

    Multidisciplinary perspectives on Artificial Intelligence and the law

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    This open access book presents an interdisciplinary, multi-authored, edited collection of chapters on Artificial Intelligence (‘AI’) and the Law. AI technology has come to play a central role in the modern data economy. Through a combination of increased computing power, the growing availability of data and the advancement of algorithms, AI has now become an umbrella term for some of the most transformational technological breakthroughs of this age. The importance of AI stems from both the opportunities that it offers and the challenges that it entails. While AI applications hold the promise of economic growth and efficiency gains, they also create significant risks and uncertainty. The potential and perils of AI have thus come to dominate modern discussions of technology and ethics – and although AI was initially allowed to largely develop without guidelines or rules, few would deny that the law is set to play a fundamental role in shaping the future of AI. As the debate over AI is far from over, the need for rigorous analysis has never been greater. This book thus brings together contributors from different fields and backgrounds to explore how the law might provide answers to some of the most pressing questions raised by AI. An outcome of the Católica Research Centre for the Future of Law and its interdisciplinary working group on Law and Artificial Intelligence, it includes contributions by leading scholars in the fields of technology, ethics and the law.info:eu-repo/semantics/publishedVersio

    "It's not a career": Platform work among young people aged 16-19

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    In the online gig economy, or platform work as it is sometimes known, work can be organised through websites and smartphone apps. People can drive for Uber or Deliveroo, sell items on eBay or Etsy, or rent their properties on Airbnb. This research examines the views of young people between the ages of 16 and 19 in the United Kingdom to see whether they knew about the online gig economy, whether they were using it already to earn money, and whether they expected to use it for their careers. It discovers careers professionals’ levels of knowledge, and their ability (and desire) to include the gig economy in their professional practice. This research contributes to discussions about what constitutes decent work, and whether it can be found within the online gig economy. The results point to ways in which careers practice could include platform work as a means of extending young people’s knowledge about alternative forms of work. This study also makes a theoretical contribution to literature, bringing together elements of careership, cognitive schema theory, and motivational theory and psychology of working theory, in a novel combination, to explain how young people were thinking about platform work in the context of their careers

    On the robustness of Bayesian phylogenetic gene tree estimation

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    Conversations on Empathy

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    In the aftermath of a global pandemic, amidst new and ongoing wars, genocide, inequality, and staggering ecological collapse, some in the public and political arena have argued that we are in desperate need of greater empathy — be this with our neighbours, refugees, war victims, the vulnerable or disappearing animal and plant species. This interdisciplinary volume asks the crucial questions: How does a better understanding of empathy contribute, if at all, to our understanding of others? How is it implicated in the ways we perceive, understand and constitute others as subjects? Conversations on Empathy examines how empathy might be enacted and experienced either as a way to highlight forms of otherness or, instead, to overcome what might otherwise appear to be irreducible differences. It explores the ways in which empathy enables us to understand, imagine and create sameness and otherness in our everyday intersubjective encounters focusing on a varied range of "radical others" – others who are perceived as being dramatically different from oneself. With a focus on the importance of empathy to understand difference, the book contends that the role of empathy is critical, now more than ever, for thinking about local and global challenges of interconnectedness, care and justice

    Diet and Sex Effects on Nutrient Handling in The Liver

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    The prevalence of obesity and metabolic disease is increasing globally, driven by gene-environment interactions, often determined in-utero. Carbohydrates are the most abundant macronutrient, and the glycaemic index (GI) measures their quality based on postprandial blood glucose response, with lower GI foods associated with improved health. However, fructose, a saccharide in sucrose, has a low GI but when overconsumed manifests metabolic disease. This thesis investigates the effects of saccharides across the lifespan on metabolic health in rodents. A meta-analysis of high-sugar rodent studies revealed altered liver phenotype and glucose tolerance but not weight or energy intake. A lack of adiposity data and female cohorts were noticeable. To address this, female C57Bl6/J mice were assigned a control (AIN93G), or a high-sugar diet comprised of one of the following: glucose, sucrose or isomaltulose. Animals were metabolically phenotyped throughout their lifespan. Glucose diets promoted increased body weight and adiposity in both generations. Sucrose dams were fatter, had larger livers and more hepatic steatosis. Lifelong sucrose exposure did not affect pup body weight or composition but increased food intake, liver size and NASH risk. Pups exposed to sucrose in-utero, had stagnated body weight and adiposity after 6-weeks, altered insulin response and increased NASH risk, without steatosis. Offspring who received sucrose postnatally were heavier, fatter, ate more, and had increased NASH risk with steatosis. Isomaltulose pups had a phenotype similar to lifelong sucrose pups. While high-sugar feeding did not produce an obesogenic phenotype, it is evident that fructose containing sugars have GI-independent effects that harm metabolic health. Additionally, a mismatch in pre- and post-natal environments contributes to metabolic dysregulation. Our findings suggest that high-sugar feeding, at any life stage leads to sub-optimal metabolic health, regardless of GI

    Embers of Autoregression: Understanding Large Language Models Through the Problem They are Trained to Solve

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    The widespread adoption of large language models (LLMs) makes it important to recognize their strengths and limitations. We argue that in order to develop a holistic understanding of these systems we need to consider the problem that they were trained to solve: next-word prediction over Internet text. By recognizing the pressures that this task exerts we can make predictions about the strategies that LLMs will adopt, allowing us to reason about when they will succeed or fail. This approach - which we call the teleological approach - leads us to identify three factors that we hypothesize will influence LLM accuracy: the probability of the task to be performed, the probability of the target output, and the probability of the provided input. We predict that LLMs will achieve higher accuracy when these probabilities are high than when they are low - even in deterministic settings where probability should not matter. To test our predictions, we evaluate two LLMs (GPT-3.5 and GPT-4) on eleven tasks, and we find robust evidence that LLMs are influenced by probability in the ways that we have hypothesized. In many cases, the experiments reveal surprising failure modes. For instance, GPT-4's accuracy at decoding a simple cipher is 51% when the output is a high-probability word sequence but only 13% when it is low-probability. These results show that AI practitioners should be careful about using LLMs in low-probability situations. More broadly, we conclude that we should not evaluate LLMs as if they are humans but should instead treat them as a distinct type of system - one that has been shaped by its own particular set of pressures.Comment: 50 pages plus 11 page of references and 23 pages of appendice

    Synthetic Data and Public Policy: supporting real-world policymakers with algorithmically generated data

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    Good policy is best developed by drawing on a wide array of high-quality evidence. The rapid growth of data science and the emergence of big datasets has materially advanced the supply and use of quantitative evidence. However, some key constraints remain, including that available datasets are still not big enough for some analytical purposes. There are also privacy and data security risks. Synthetic data is an emerging area of data science that can potentially support policy decision making through enabling research to work faster and with fewer errors while also ensuring privacy and security
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