21,086 research outputs found
RankPL: A Qualitative Probabilistic Programming Language
In this paper we introduce RankPL, a modeling language that can be thought of
as a qualitative variant of a probabilistic programming language with a
semantics based on Spohn's ranking theory. Broadly speaking, RankPL can be used
to represent and reason about processes that exhibit uncertainty expressible by
distinguishing "normal" from" surprising" events. RankPL allows (iterated)
revision of rankings over alternative program states and supports various types
of reasoning, including abduction and causal inference. We present the
language, its denotational semantics, and a number of practical examples. We
also discuss an implementation of RankPL that is available for download
Are Reasons Causally Relevant for Action? Dharmakīrti and the Embodied Cognition Paradigm
How do mental states come to be about something other than their own operations, and thus to serve as ground for effective action? This papers argues that causation in the mental domain should be understood to function on principles of intelligibility (that is, on principles which make it perfectly intelligible for intentions to have a causal role in initiating behavior) rather than on principles of mechanism (that is, on principles which explain how causation works in the physical domain). The paper considers DharmakÄ«rtiâs kÄryÄnumÄna argument (that is, the argument that an inference is sound only when one infers from the effect to the cause and not vice versa), and proposes a naturalized account of reasons. On this account, careful scrutiny of the effect can provide a basis for ascertaining the unique causal totality that is its source, but only for reasoning that is contextâspecific
Causal graphical models in systems genetics: A unified framework for joint inference of causal network and genetic architecture for correlated phenotypes
Causal inference approaches in systems genetics exploit quantitative trait
loci (QTL) genotypes to infer causal relationships among phenotypes. The
genetic architecture of each phenotype may be complex, and poorly estimated
genetic architectures may compromise the inference of causal relationships
among phenotypes. Existing methods assume QTLs are known or inferred without
regard to the phenotype network structure. In this paper we develop a
QTL-driven phenotype network method (QTLnet) to jointly infer a causal
phenotype network and associated genetic architecture for sets of correlated
phenotypes. Randomization of alleles during meiosis and the unidirectional
influence of genotype on phenotype allow the inference of QTLs causal to
phenotypes. Causal relationships among phenotypes can be inferred using these
QTL nodes, enabling us to distinguish among phenotype networks that would
otherwise be distribution equivalent. We jointly model phenotypes and QTLs
using homogeneous conditional Gaussian regression models, and we derive a
graphical criterion for distribution equivalence. We validate the QTLnet
approach in a simulation study. Finally, we illustrate with simulated data and
a real example how QTLnet can be used to infer both direct and indirect effects
of QTLs and phenotypes that co-map to a genomic region.Comment: Published in at http://dx.doi.org/10.1214/09-AOAS288 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Learning Bayesian Networks with the bnlearn R Package
bnlearn is an R package which includes several algorithms for learning the
structure of Bayesian networks with either discrete or continuous variables.
Both constraint-based and score-based algorithms are implemented, and can use
the functionality provided by the snow package to improve their performance via
parallel computing. Several network scores and conditional independence
algorithms are available for both the learning algorithms and independent use.
Advanced plotting options are provided by the Rgraphviz package.Comment: 22 pages, 4 picture
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