A Computational Mechanism for Unified Gain and Timing Control in the Cerebellum

Precise gain and timing control is the goal of cerebellar motor learning. Because the basic neural circuitry of the cerebellum is homogeneous throughout the cerebellar cortex, a single computational mechanism may be used for simultaneous gain and timing control. Although many computational models of the cerebellum have been proposed for either gain or timing control, few models have aimed to unify them. In this paper, we hypothesize that gain and timing control can be unified by learning of the complete waveform of the desired movement profile instructed by climbing fiber signals. To justify our hypothesis, we adopted a large-scale spiking network model of the cerebellum, which was originally developed for cerebellar timing mechanisms to explain the experimental data of Pavlovian delay eyeblink conditioning, to the gain adaptation of optokinetic response (OKR) eye movements. By conducting large-scale computer simulations, we could reproduce some features of OKR adaptation, such as the learning-related change of simple spike firing of model Purkinje cells and vestibular nuclear neurons, simulated gain increase, and frequency-dependent gain increase. These results suggest that the cerebellum may use a single computational mechanism to control gain and timing simultaneously

A model study of cellular short-term memory produced by slowly inactivating potassium conductances

Abstract. We analyzed the cellular short-term memory effects induced by a slowly inactivating potassium (Ks) conductance using a biophysical model of a neuron. We first described latency-to-first-spike and temporal changes in firing frequency as a function of parameters of the model, injected current and prior history of the neuron (deinactivation level) under current clamp. This provided a complete set of properties describing the Ks conductance in a neuron. We then showed that the action of the Ks conductance is not generally appropriate for controlling latency-to-first-spike under random synaptic stimulation. However, reliable latencies were found when neuronal population computation was used. Ks inactivation was found to control the rate of convergence to steady-state discharge behavior and to allow frequency to increase at variable rates in sets of synaptically connected neurons. These results suggest that inactivation of the Ks conductance can have a reliable influence on the behavior of neuronal populations under real physiological conditions

Deep Learning Techniques for Music Generation -- A Survey

This paper is a survey and an analysis of different ways of using deep learning (deep artificial neural networks) to generate musical content. We propose a methodology based on five dimensions for our analysis: Objective - What musical content is to be generated? Examples are: melody, polyphony, accompaniment or counterpoint. - For what destination and for what use? To be performed by a human(s) (in the case of a musical score), or by a machine (in the case of an audio file). Representation - What are the concepts to be manipulated? Examples are: waveform, spectrogram, note, chord, meter and beat. - What format is to be used? Examples are: MIDI, piano roll or text. - How will the representation be encoded? Examples are: scalar, one-hot or many-hot. Architecture - What type(s) of deep neural network is (are) to be used? Examples are: feedforward network, recurrent network, autoencoder or generative adversarial networks. Challenge - What are the limitations and open challenges? Examples are: variability, interactivity and creativity. Strategy - How do we model and control the process of generation? Examples are: single-step feedforward, iterative feedforward, sampling or input manipulation. For each dimension, we conduct a comparative analysis of various models and techniques and we propose some tentative multidimensional typology. This typology is bottom-up, based on the analysis of many existing deep-learning based systems for music generation selected from the relevant literature. These systems are described and are used to exemplify the various choices of objective, representation, architecture, challenge and strategy. The last section includes some discussion and some prospects.Comment: 209 pages. This paper is a simplified version of the book: J.-P. Briot, G. Hadjeres and F.-D. Pachet, Deep Learning Techniques for Music Generation, Computational Synthesis and Creative Systems, Springer, 201

Centering in parallel channel systems

Several types of signal processing systems in which the signal flows along parallel channels in a fashion similar to the auditory system have been investigated. The effect of excitation with signals containing both single and multiple spectral peaks (formants) was considered. In particular, the effect of nonlinear interaction between channels, referred to as centering, in the presence of noise was studied. These systems were investigated for their value, both as information processing networks and as models of the auditory system. The analysis indicates that parallel channel systems, in general, exhibit excellent performance in the presence of noise, and that a parallel channel system, with a limited overall bandwidth, can be made to process large amounts of information per unit time if used in conjunction with an appropriate centering network. Furthermore, these systems permit detailed frequency analysis of signals in the presence of noise without impairing their temporal discrimination capability. Of the centering processes investigated, maximum likelihood centering provides an optimum estimate of formant frequency in the presence of noise, while lateral inhibitory centering probably represents the most practical process for implementation. The performances of various centering processes are compared to the known characteristics of the auditory system, and the most promising of these, lateral inhibitory centering, is employed in a model of the peripheral auditory system. The response of this model, when simulated on the digital computer, correlates closely with many of the characteristics of the peripheral auditory system. The model, however, does not adequately explain the spectral resolving ability displayed by the ear. An extension of the model was suggested which should not be subject to this limitation

A model study of cellular short-term memory produced by slowly inactivating potassium conductances

Abstract. We analyzed the cellular short-term memory effects induced by a slowly inactivating potassium (Ks) conductance using a biophysical model of a neuron. We first described latency-to-first-spike and temporal changes in firing frequency as a function of parameters of the model, injected current and prior history of the neuron (deinactivation level) under current clamp. This provided a complete set of properties describing the Ks conductance in a neuron. We then showed that the action of the Ks conductance is not generally appropriate for controlling latency-to-first-spike under random synaptic stimulation. However, reliable latencies were found when neuronal population computation was used. Ks inactivation was found to control the rate of convergence to steady-state discharge behavior and to allow frequency to increase at variable rates in sets of synaptically connected neurons. These results suggest that inactivation of the Ks conductance can have a reliable influence on the behavior of neuronal populations under real physiological conditions

Supervised Land Use Inference from Mobility Patterns

This paper addresses the relationship between land use and mobility patterns. Since each particular zone directly feeds the global mobility once acting as origin of trips and others as destination, both roles are simultaneously used for predicting land uses. Specifically this investigation uses mobility data derived from mobile phones, a technology that emerges as a useful, quick data source on people's daily mobility, collected during two weeks over the urban area of Málaga (Spain). This allows exploring the relevance of integrating weekday-weekend trip information to better determine the category of land use. First, this work classifies patterns on trips originated and terminated in each zone into groups by means of a clustering approach. Based on identifiable relationships between activity and times when travel peaks appear, a preliminary categorization of uses is provided. Then, both grouping results are used as input variables in a K-nearest neighbors (KNN) classification model to determine the exact land use. The KNN method assumes that the category of an object must be similar to the category of the closest neighbors. After training the models, the findings reveal that this approach provides a precise land use categorization, yielding the best accuracy results for the major categories of land uses in the studied area. Moreover, as a result, the weekend data certainly contributes to finding more precise land uses as those obtained by just weekday data. In particular, the percentage of correctly predicted categories using both weekday and weekend is around 80%, while just weekday data reach 67%. The comparison with actual land uses also demonstrates that this approach is able to provide useful information, identifying zones with a specific clear dominant use (residential, industrial, and commercial), as well as multiactivity zones (mixed). This fact is especially useful in the context of urban environments where multiple activities coexist.Unión Europea Programa Operativo FEDER de Andalucía 2011–2015Ministerio de Economía y Competitividad PTQ-13-0642