Noncontact Electrical Permittivity Mapping and pH-Sensitive Films for Osseointegrated Prosthesis and Infection Monitoring.

The objective of this paper is to develop a noncontact, noninvasive system for detecting and monitoring subcutaneous infection occurring at the tissue and osseointegrated prosthesis interface. It is known that the local pH of tissue can change due to infection. Therefore, the sensing system integrates two parts, namely, pH-sensitive thin films that can be coated onto prosthesis surfaces prior to them being implanted and an electrical capacitance tomography (ECT) algorithm that can reconstruct the spatial permittivity distribution of a region of space in a noncontact fashion. First, a thin film pH sensor was fabricated by spray coating, and tests confirmed that the film exhibited changes in its permittivity due to pH. Second, the ECT forward and inverse problems were implemented. Third, an aluminum rod was employed as a representative phantom of an osseointegrated prosthesis and then spray coated with the pH sensor. Finally, the film-coated phantom was immersed in different pH buffers, dried, and subjected to ECT interrogation and spatial permittivity reconstruction. The results validated that ECT was able to detect and localize permittivity variations correlated to pH changes

Monitoring osseointegrated prosthesis loosening and fracture using electrical capacitance tomography.

A noncontact, noninvasive, electrical permittivity imaging technique is proposed for monitoring loosening of osseointegrated prostheses and bone fracture. The proposed method utilizes electrical capacitance tomography (ECT), which employs a set of noncontact electrodes, arranged in a circular fashion around the imaging area, for electrical excitations and measurements. An inverse reconstruction algorithm was developed and implemented to reconstruct the electrical permittivity distribution of the interrogated region from boundary capacitance measurements. In this study, osseointegrated prosthesis phantoms were prepared using plastic rods and Sawbone femur specimens, which were subjected to prosthesis loosening and fracture monitoring tests. The results demonstrated that the spatial location and extent of prosthesis loosening and bone fracture could be estimated from the ECT reconstructed permittivity maps. The resolution of the reconstructed images was further enhanced by a limited region tomography algorithm, and its accuracy in terms of identifying the severity, location, and shape of bone fracture was also investigated and compared with conventional full region tomography

Combining Radon transform and Electrical Capacitance Tomography for a 2d+12d+1 imaging device

This paper describes a coplanar non invasive non destructive capacitive imaging device. We first introduce a mathematical model for its output, and discuss some of its theoretical capabilities. We show that the data obtained from this device can be interpreted as a weighted Radon transform of the electrical permittivity of the measured object near its surface. Image reconstructions from experimental data provide good surface resolution as well as short depth imaging, making the apparatus a $2d+1$ imager. The quality of the images leads us to expect that excellent results can be delivered by \emph{ad-hoc} optimized inversion formulas. There are also interesting, yet unexplored, theoretical questions on imaging that this sensor will allow to test

Noncontact Electrical Permittivity Mapping and pH-Sensitive Films for Osseointegrated Prosthesis and Infection Monitoring.

The objective of this paper is to develop a noncontact, noninvasive system for detecting and monitoring subcutaneous infection occurring at the tissue and osseointegrated prosthesis interface. It is known that the local pH of tissue can change due to infection. Therefore, the sensing system integrates two parts, namely, pH-sensitive thin films that can be coated onto prosthesis surfaces prior to them being implanted and an electrical capacitance tomography (ECT) algorithm that can reconstruct the spatial permittivity distribution of a region of space in a noncontact fashion. First, a thin film pH sensor was fabricated by spray coating, and tests confirmed that the film exhibited changes in its permittivity due to pH. Second, the ECT forward and inverse problems were implemented. Third, an aluminum rod was employed as a representative phantom of an osseointegrated prosthesis and then spray coated with the pH sensor. Finally, the film-coated phantom was immersed in different pH buffers, dried, and subjected to ECT interrogation and spatial permittivity reconstruction. The results validated that ECT was able to detect and localize permittivity variations correlated to pH changes