Machine learning methods for histopathological image analysis

Abundant accumulation of digital histopathological images has led to the increased demand for their analysis, such as computer-aided diagnosis using machine learning techniques. However, digital pathological images and related tasks have some issues to be considered. In this mini-review, we introduce the application of digital pathological image analysis using machine learning algorithms, address some problems specific to such analysis, and propose possible solutions.Comment: 23 pages, 4 figure

Weakly Labelled AudioSet Tagging with Attention Neural Networks

Audio tagging is the task of predicting the presence or absence of sound classes within an audio clip. Previous work in audio tagging focused on relatively small datasets limited to recognising a small number of sound classes. We investigate audio tagging on AudioSet, which is a dataset consisting of over 2 million audio clips and 527 classes. AudioSet is weakly labelled, in that only the presence or absence of sound classes is known for each clip, while the onset and offset times are unknown. To address the weakly-labelled audio tagging problem, we propose attention neural networks as a way to attend the most salient parts of an audio clip. We bridge the connection between attention neural networks and multiple instance learning (MIL) methods, and propose decision-level and feature-level attention neural networks for audio tagging. We investigate attention neural networks modeled by different functions, depths and widths. Experiments on AudioSet show that the feature-level attention neural network achieves a state-of-the-art mean average precision (mAP) of 0.369, outperforming the best multiple instance learning (MIL) method of 0.317 and Google's deep neural network baseline of 0.314. In addition, we discover that the audio tagging performance on AudioSet embedding features has a weak correlation with the number of training samples and the quality of labels of each sound class.Comment: 13 page

One-Class Classification: Taxonomy of Study and Review of Techniques

One-class classification (OCC) algorithms aim to build classification models when the negative class is either absent, poorly sampled or not well defined. This unique situation constrains the learning of efficient classifiers by defining class boundary just with the knowledge of positive class. The OCC problem has been considered and applied under many research themes, such as outlier/novelty detection and concept learning. In this paper we present a unified view of the general problem of OCC by presenting a taxonomy of study for OCC problems, which is based on the availability of training data, algorithms used and the application domains applied. We further delve into each of the categories of the proposed taxonomy and present a comprehensive literature review of the OCC algorithms, techniques and methodologies with a focus on their significance, limitations and applications. We conclude our paper by discussing some open research problems in the field of OCC and present our vision for future research.Comment: 24 pages + 11 pages of references, 8 figure

Deep learning in remote sensing: a review

Standing at the paradigm shift towards data-intensive science, machine learning techniques are becoming increasingly important. In particular, as a major breakthrough in the field, deep learning has proven as an extremely powerful tool in many fields. Shall we embrace deep learning as the key to all? Or, should we resist a 'black-box' solution? There are controversial opinions in the remote sensing community. In this article, we analyze the challenges of using deep learning for remote sensing data analysis, review the recent advances, and provide resources to make deep learning in remote sensing ridiculously simple to start with. More importantly, we advocate remote sensing scientists to bring their expertise into deep learning, and use it as an implicit general model to tackle unprecedented large-scale influential challenges, such as climate change and urbanization.Comment: Accepted for publication IEEE Geoscience and Remote Sensing Magazin

Learning and Interpreting Multi-Multi-Instance Learning Networks

We introduce an extension of the multi-instance learning problem where examples are organized as nested bags of instances (e.g., a document could be represented as a bag of sentences, which in turn are bags of words). This framework can be useful in various scenarios, such as text and image classification, but also supervised learning over graphs. As a further advantage, multi-multi instance learning enables a particular way of interpreting predictions and the decision function. Our approach is based on a special neural network layer, called bag-layer, whose units aggregate bags of inputs of arbitrary size. We prove theoretically that the associated class of functions contains all Boolean functions over sets of sets of instances and we provide empirical evidence that functions of this kind can be actually learned on semi-synthetic datasets. We finally present experiments on text classification, on citation graphs, and social graph data, which show that our model obtains competitive results with respect to accuracy when compared to other approaches such as convolutional networks on graphs, while at the same time it supports a general approach to interpret the learnt model, as well as explain individual predictions.Comment: JML