21,374 research outputs found
Application of neural networks and sensitivity analysis to improved prediction of trauma survival
Application of neural networks and sensitivity analysis to improved prediction of trauma surviva
Deep generative modeling for single-cell transcriptomics.
Single-cell transcriptome measurements can reveal unexplored biological diversity, but they suffer from technical noise and bias that must be modeled to account for the resulting uncertainty in downstream analyses. Here we introduce single-cell variational inference (scVI), a ready-to-use scalable framework for the probabilistic representation and analysis of gene expression in single cells ( https://github.com/YosefLab/scVI ). scVI uses stochastic optimization and deep neural networks to aggregate information across similar cells and genes and to approximate the distributions that underlie observed expression values, while accounting for batch effects and limited sensitivity. We used scVI for a range of fundamental analysis tasks including batch correction, visualization, clustering, and differential expression, and achieved high accuracy for each task
RADNET: Radiologist Level Accuracy using Deep Learning for HEMORRHAGE detection in CT Scans
We describe a deep learning approach for automated brain hemorrhage detection
from computed tomography (CT) scans. Our model emulates the procedure followed
by radiologists to analyse a 3D CT scan in real-world. Similar to radiologists,
the model sifts through 2D cross-sectional slices while paying close attention
to potential hemorrhagic regions. Further, the model utilizes 3D context from
neighboring slices to improve predictions at each slice and subsequently,
aggregates the slice-level predictions to provide diagnosis at CT level. We
refer to our proposed approach as Recurrent Attention DenseNet (RADnet) as it
employs original DenseNet architecture along with adding the components of
attention for slice level predictions and recurrent neural network layer for
incorporating 3D context. The real-world performance of RADnet has been
benchmarked against independent analysis performed by three senior radiologists
for 77 brain CTs. RADnet demonstrates 81.82% hemorrhage prediction accuracy at
CT level that is comparable to radiologists. Further, RADnet achieves higher
recall than two of the three radiologists, which is remarkable.Comment: Accepted at IEEE Symposium on Biomedical Imaging (ISBI) 2018 as
conference pape
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