1 research outputs found
Areas of Effectiveness of Half-Sine Monophasic and Biphasic Depolarizing Defibrillation Pulses on the Diagram of Energy / Phase of Fibrillation Cycle
ΠΠ»Π°Π³ΠΎΠ΄Π°ΡΠΈΠΌ ΠΠ Β«ΠΠ Β«Π£ΠΠΠΒ», Π² Π»ΠΈΡΠ΅ Π³Π»Π°Π²Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΎΡΠ° ΠΠ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΠΈΠ·Π΄Π΅Π»ΠΈΠΉ Π§ΡΠΏΠΎΠ²Π° ΠΠ»Π΅ΠΊΡΠ΅Ρ ΠΠ»Π΅ΠΊΡΠ°Π½Π΄ΡΠΎΠ²ΠΈΡΠ°, Π·Π° Π°ΠΊΡΠΈΠ²Π½ΠΎΠ΅ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ ΠΏΡΠΈΠΊΠ»Π°Π΄Π½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Π² ΠΎΠ±Π»Π°ΡΡΠΈ ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π΄Π΅ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΈ.ΠΠΎΡΡΡΠΏΠΈΠ»Π°: 15.12.2021. ΠΡΠΈΠ½ΡΡΠ° Π² ΠΏΠ΅ΡΠ°ΡΡ: 12.01.2022.We are grateful to JSC PA UOMZ, represented by the chief designer of the design bureau of medical devices, Aleksey A. Chupov, for the active development of applied research in the field of electrical defibrillation.Received: 15.12.2021. Accepted: 12.01.2022.Π¦Π΅Π»ΡΡ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΠΎΠ±Π»Π°ΡΡΠ΅ΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΏΠΎΠ»ΡΡΠΈΠ½ΡΡΠΎΠΈΠ΄Π°Π»ΡΠ½ΡΡ
ΠΌΠΎΠ½ΠΎΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΠΈ Π±ΠΈΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ Π΄Π΅ΠΏΠΎΠ»ΡΡΠΈΠ·ΡΡΡΠΈΡ
Π΄Π΅ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΎΠ½Π½ΡΡ
ΠΈΠΌΠΏΡΠ»ΡΡΠΎΠ² Π½Π° Π΄ΠΈΠ°Π³ΡΠ°ΠΌΠΌΠ΅ ΡΠ½Π΅ΡΠ³ΠΈΡ / ΡΠ°Π·Π° ΡΠΈΠΊΠ»Π° ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΈ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, ΡΡΠΎ ΠΎΠ±Π»Π°ΡΡΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Ρ ΠΌΠΎΠ½ΠΎΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΠΈ Π±ΠΈΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ Π΄Π΅ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΎΠ½Π½ΡΡ
ΠΈΠΌΠΏΡΠ»ΡΡΠΎΠ² ΠΈΠΌΠ΅ΡΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠ΅ ΡΠ°Π·Π»ΠΈΡΠΈΠ΅. Π£ Π±ΠΈΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΠΈΠΌΠΏΡΠ»ΡΡΠ° Π΄ΠΎΠ»Ρ ΡΠΈΠΊΠ»Π° ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΈ, Π½Π° ΠΊΠΎΡΠΎΡΠΎΠΉ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°Π΅ΡΡΡ ΡΠ΄Π»ΠΈΠ½Π΅Π½ΠΈΠ΅ ΡΠ΅ΡΡΠ°ΠΊΡΠ΅ΡΠ½ΠΎΡΡΠΈ, ΠΏΡΠΈ Π½ΠΈΠ·ΠΊΠΈΡ
Π·Π½Π°ΡΠ΅Π½ΠΈΡΡ
ΡΠ½Π΅ΡΠ³ΠΈΠΈ Π΄Π΅ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΈΠΌΠΏΡΠ»ΡΡΠ° ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ ΠΏΡΠ΅Π²ΡΡΠ°Π΅Ρ ΡΠ°ΠΊΠΎΠ²ΡΡ Ρ ΠΌΠΎΠ½ΠΎΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΠΈΠΌΠΏΡΠ»ΡΡΠ°. ΠΠΎΠΆΠ½ΠΎ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»ΠΎΠΆΠΈΡΡ, ΡΡΠΎ ΡΡΠΈΠΌ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°Π΅ΡΡΡ ΡΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΏΡΠ΅ΠΈΠΌΡΡΠ΅ΡΡΠ²ΠΎ Π±ΠΈΠΏΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΠΈΠΌΠΏΡΠ»ΡΡΠ° Π΄Π΅ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΈ ΠΏΠ΅ΡΠ΅Π΄ ΠΌΠΎΠ½ΠΎΠΏΠΎΠ»ΡΡΠ½ΡΠΌ.The aim of this study is to compare the areas of effectiveness of half-sine monophasic and biphasic depolarizing defibrillation pulses in the diagram of energy / phase of fibrillation cycle. The study was carried out on the ten Tusscher-Panfilov 2006 model of the human ventricular myocyte under the influence of simulated fibrillation in the BeatBox simulation environment under the Fedora operating system. The simulation was carried out on a computer under the Windows 10 operating system, the Fedora operating system was implemented in the Oracle VM VirtualBox virtualization environment. The results of computer simulations have shown that the areas of effectiveness for monophasic and biphasic defibrillation pulses are significantly different. In a biphasic pulse, the fraction of a fibrillation cycle at which refractoriness is extended is significantly higher than that of a monophasic pulse at low defibrillation pulse energies. It can be assumed that this provides the energy advantage of a biphasic defibrillation pulse over a monophasic one.ΠΠ°ΡΡΠΎΡΡΠΈΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΠΏΠΎΠ»Π½Π΅Π½Ρ ΠΏΡΠΈ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΎΠ΅ΠΊΡΠ° Β«Π‘ΠΎΠ·Π΄Π°Π½ΠΈΠ΅ Π²ΡΡΠΎΠΊΠΎΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π° ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΠΈΠ·Π΄Π΅Π»ΠΈΠΉ Π΄Π»Ρ Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΡ ΡΡΠ½ΠΊΡΠΈΠΈ ΡΠ΅ΡΠ΄ΡΠ° Π² ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΠ΅ ΠΎΠ±ΡΠ΅Π΄ΠΎΡΡΡΠΏΠ½ΠΎΠΉ Π΄Π΅ΡΠΈΠ±ΡΠΈΠ»Π»ΡΡΠΈΠΈΒ».This research was carried out during the implementation of the project βCreation of high-tech production of medical devices for the restoration of heart function to ensure public defibrillationβ