5,161 research outputs found
Spartan Daily, October 20, 1959
Volume 47, Issue 20https://scholarworks.sjsu.edu/spartandaily/3936/thumbnail.jp
Computational fluid dynamics
An overview of computational fluid dynamics (CFD) activities at the Langley Research Center is given. The role of supercomputers in CFD research, algorithm development, multigrid approaches to computational fluid flows, aerodynamics computer programs, computational grid generation, turbulence research, and studies of rarefied gas flows are among the topics that are briefly surveyed
Modeling and Simulation of the Effects of Cyclic Loading on Articular Cartilage Lesion Formation
We present a model of articular cartilage lesion formation to simulate the
effects of cyclic loading. This model extends and modifies the
reaction-diffusion-delay model by Graham et al. 2012 for the spread of a lesion
formed though a single traumatic event. Our model represents "implicitly" the
effects of loading, meaning through a cyclic sink term in the equations for
live cells.
Our model forms the basis for in silico studies of cartilage damage relevant
to questions in osteoarthritis, for example, that may not be easily answered
through in vivo or in vitro studies.
Computational results are presented that indicate the impact of differing
levels of EPO on articular cartilage lesion abatement
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